Freiburg shocked champions Bayern Munich with an 89th-minute equaliser from Lucas Holer to earn a deserved point with a 1-1 draw in the Bundesliga on Saturday.
Marcus Rashford scored a winner deep into stoppage time as Manchester United snatched a victory against Bournemouth at the Vitality.
French champions Paris Saint-Germain beat Lille 2-1 in Ligue 1 on Friday to break the record for the best start to a season in Europe's top five leagues with their 12th successive win.
Napoli forward Dries Mertens scored a hat-trick to lead his side to a 5-1 rout of Empoli in Serie A on Friday, moving them back into second place in the standings.
Borussia Dortmund needed a Marco Reus penalty late in extra time to beat second division Union Berlin 3-2 on Wednesday and book their spot in the DFB Pokal third round.
Holders Barcelona scraped a 1-0 win at third-tier Cultural Leonesa thanks to Clement Lenglet's late header in their Copa del Rey first-leg match.
Santiago Solari got off to the perfect start as Real Madrid's interim coach when his side thrashed Melilla 4-0 in the Copa del Rey on Wednesday.
Tottenham Hotspur beat West Ham United 3-1 at the London Stadium with Son Heung-Min scoring in each half to book a place in the quarterfinals of the Carabao Cup.
Chelsea reached the League Cup quarterfinals thanks to two own goals in a 3-2 win over second-tier Derby County on Wednesday as Frank Lampard's return to his former club ended in disappointment.
Arsenal held off Blackpool for a 2-1 Carabao Cup win at the Emirates on Wednesday in a match that saw both team's finish with 10 players.
AC Milan defender Alessio Romagnoli put through his own net and scored a freakish stoppage-time goal in a dramatic 2-1 win over Genoa in Serie A on Wednesday.
Champions Bayern Munich were made to work hard before edging amateurs SV Rodinghausen 2-1 on Tuesday to advance to the DFB Pokal third round.
Real Madrid have sacked Julen Lopetegui after just four months in charge, with the ex-Spain coach paying the price following Sunday's 5-1 humiliation against Barcelona in El Clasico.
Manchester City returned to the Premier League summit on goal difference with a 1-0 victory over fifth-placed Tottenham Hotspur courtesy of an early goal by Riyad Mahrez at a subdued Wembley Stadium on Monday.
Inter Milan captain Mauro Icardi scored twice as they beat Lazio 3-0 away on Monday with an impressive all-round performance to claim their sixth Serie A win in a row.
Kylian Mbappe came off the bench and used his electrifying pace to score one and help create another as Paris Saint-Germain won 2-0 at bitter rivals Marseille on Sunday in a fiery match that saw both managers sent off after arguing with officials.
Napoli substitute Dries Mertens scored a last-minute goal to salvage a 1-1 draw against AS Roma in Serie A on Sunday although they slipped further off the title pace as their 100 percent home record ended.
AC Milan lifted the pressure on beleaguered coach Gennaro Gattuso when a second-half strike by Suso gave them a 3-2 win over Sampdoria in a see-saw Serie A match on Sunday.
Manchester United bounced back from a disappointing week to beat Everton 2-1 at Old Trafford.
Chelsea went second in the Premier League with an emphatic 4-0 win at Burnley on Sunday which maintained their unbeaten start to the season.
Arsenal's 11-match winning run came to an end with a controversial 2-2 draw at Crystal Palace
Barcelona forward Luis Suarez scored a hat-trick as his side thrashed arch-rivals Real Madrid 5-1 on Sunday in a highly entertaining Clasico which surely will signal the end of hapless coach Julen Lopetegui's spell in charge of Real.
Former France World Cup winner Thierry Henry was denied a first taste of success as Monaco manager after a rollercoaster 2-2 home draw with Dijon on Saturday stretched their winless run to 10 games.
Cristiano Ronaldo scored twice, the first a penalty and the second a booming long-range shot, to give Juventus a 2-1 win at Empoli on Saturday after their lowly Serie A opponents took a shock first-half lead.
Atletico Madrid climbed to the top of La Liga with a comfortable 2-0 win at home to Real Sociedad on Saturday, easing the pain of their humbling 4-0 defeat at Borussia Dortmund in the Champions League in midweek.
Liverpool moved top of the Premier League on Saturday but their "creative mood" almost cost them, manager Juergen Klopp said after lowly Cardiff City briefly threatened a comeback before the Reds ran out 4-1 winners at Anfield.
Salomon Kalou scored twice, including a stoppage-time penalty, to earn Hertha Berlin a last-gasp 2-2 draw at Bundesliga leaders Borussia Dortmund on Saturday.
Champions Bayern Munich cut the gap to leaders Borussia Dortmund but were far from impressive in their 2-1 victory at Mainz 05 on Saturday as they made it three wins in three matches in all competitions following their early-season dip in form.
Ruben Loftus-Cheek scored three goals as Chelsea dispatched BATE Borisov 3-1 in Europa League action on Thursday.
Real Betis stunned AC Milan with a 2-1 win at the San Siro in Europa League group play on Thursday.
Real Madrid midfielder Luka Modric has ended the Cristiano Ronaldo-Lionel Messi stranglehold on the Ballon d'Or.
Two first-half goals gave Paris Saint-Germain a crucial 2-1 Champions League home win over Liverpool, putting them in a great position to qualify and leaving Jurgen Klopp's side, finalists last season, in danger of elimination.
Napoli swept aside Red Star Belgrade with a typically entertaining performance as two goals from Dries Mertens helped them to a 3-1 win over the former European champions in their Champions League match on Wednesday.
Borussia Dortmund booked their spot in the Champions League knockout stage with a game to spare after a goalless draw against visitors Club Brugge in Group A on Wednesday.
Christian Eriksen kept Tottenham Hotspur's hopes of reaching the round of 16 in the Champions League alive when he came off the bench to score a late winner in his side's 1-0 victory over Inter Milan at Wembley on Wednesday.
Lionel Messi scored an excellent individual goal and laid on another as Barcelona beat PSV Eindhoven 2-1 to secure top spot in Champions League Group B on Wednesday.
Atletico Madrid clinched their place in the Champions League round of 16 on Wednesday by beating AS Monaco 2-0 at home while also ensuring that Thierry Henry's hapless visitors will now even miss out on qualification for the Europa League.
A goal in each half was enough for Lokomotiv Moscow to earn a 2-0 win over Galatasaray in Champions League Group D on Wednesday, ending Galatasaray's hopes of qualifying for the knockout stages and sending both Porto and Schalke through.
Juventus clinched a place in the Champions League knockout stages when a brilliant Cristiano Ronaldo assist set up Mario Mandzukic to give them a 1-0 win over Valencia on Tuesday.
Manchester United's Marouane Fellaini struck a controversial stoppage-time winner to bring blessed relief to Old Trafford after a laboured 1-0 win over Young Boys edged them into the Champions League last 16 on Tuesday.
Manchester City progressed to the knockout stages of the Champions League after twice coming from behind to draw 2-2 with Olympique Lyonnais in Group F on Tuesday.
Bayern Munich's Arjen Robben and Robert Lewandowski scored two goals each as the German champions demolished Benfica 5-1 on Tuesday to reach the Champions League round of 16 and lift some of the pressure off boss Niko Kovac.
Real Madrid secured first place in Champions League Group G with 2-0 victory over Roma at the Stadio Olimpico on Tuesday although the Italians are also through to round of 16.
Ajax Amsterdam reached the Champions League knockout stages for the first time since 2005-06 after a Dusan Tadic brace gave the Dutch side a 2-0 win at 10-man AEK Athens in a match marred by crowd trouble at the Olympic Stadium on Tuesday.
Cristiano Ronaldo scored a stunning first Champions League goal for Juventus but former club Manchester United fought back for a 2-1 win in Turin.
Real Madrid took a huge step towards clinching a spot in the Champions League knockout stage on Wednesday with a 5-0 rout of Viktoria Plzen as Karim Benzema scored two of four first-half goals for the Spanish giants.
Bayern Munich forward Robert Lewandowski scored once in each half to give his team a 2-0 victory over AEK Athens in the Champions League on Wednesday that put them two points clear at the top of Group E with two matches left.
Gabriel Jesus hit a hat-trick, including two penalties, as Manchester City marched closer to the knockout stage of the Champions League after crushing Ukraine's Shakhtar Donetsk 6-0 at the Etihad Stadium on Wednesday.
Ajax Amsterdam goalkeeper Andre Onana went from villain to hero as the Dutch side drew 1-1 at Benfica on Wednesday, gifting the hosts the lead before making a brilliant save with the last kick of the game to rescue a point.
Hoffenheim kept their slim hopes of extending their Champions League season afloat on Wednesday when they came back from 2-0 down to draw 2-2 with only 10 men at a rain-sodden Olympique Lyonnais.
Valencia's Carlos Soler had a hand in all three goals as they beat Young Boys 3-1 in the Champions League on Wednesday, boosting their last-16 hopes with their first home win of the season.
AS Roma put themselves on the brink of a place in the Champions League knockout stage when Lorenzo Pellegrini's first goal in the competition gave them a 2-1 win at 10-man CSKA Moscow on Wednesday.
Napoli and Paris Saint-Germain battled to a 1-1 draw in their Champions League match on Tuesday as Neymar produced a performance mixed with brilliance and petulance.
Tottenham's Champions League campaign is still alive after two late Harry Kane goals game them a 2-1 win over PSV Eindhoven at Wembley.
Porto all but guaranteed themselves a place in the knockout stage of the Champions League on Tuesday with a 4-1 win over Lokomotiv Moscow, who have yet to register a point in the competition.
Atletico Madrid dominated a toothless Borussia Dortmund to win 2-0 in their Champions League Group A match on Tuesday, exacting some revenge for last month's heavy loss in Germany and snapping their opponents' unbeaten run this season.
Barcelona qualified for the knockout stage of the Champions League on Tuesday after a compelling 1-1 draw away to Inter Milan as a late leveller from Mauro Icardi ended the Catalans' perfect record in this season's competition.
Liverpool face an uphill task to qualify for the knockout rounds of the Champions League after suffering a 2-0 defeat away to Red Star Belgrade.
Club Brugge kept their Champions League hopes alive on Tuesday with a crushing 4-0 win over AS Monaco that extended coach Thierry Henry's winless start in the principality to five games.
Mohamed Salah scored twice as Liverpool cruised to a 4-0 win over Red Star Belgrade in Champions League Group C action on Wednesday night.