Chelsea took another step towards the Premier League title with an eventful 0-0 draw at the Emirates. Referee Michael Oliver waved off three penalty decisions in the first half.
Everton scored three goals without reply at Goodison Park as Manchester United suffered a second defeat in succession.
Substitute Fernandinho struck a late winner as Manchester City killed off an Aston Villa comeback to claim a frantic 3-2 victory at the Etihad Stadium.
Liverpool's slim Champions League hopes suffered a huge blow as they were held to a disappointing 0-0 draw at West Brom.
Mauricio Pochettino frustrated the fans that once adored him as Tottenham twice came from behind to secure a draw on his first return to Southampton.
There will be no fairytale end to Steven Gerrard's Liverpool career after Aston Villa came from behind to deservedly book their place in the FA Cup final with a 2-1 win over the Reds.
Harry Kane struck yet again as Tottenham beat Newcastle 3-1 to condemn the Magpies to a sixth successive Premier League defeat and rekindle their own hopes of European qualification.
A bizarre own goal from West Ham's James Collins helped Manchester City back to winning ways in the Premier League.
A fumble from Reading goalkeeper Adam Federici in extra time handed holders Arsenal a 2-1 victory and a place in the FA Cup final.
Chelsea have one hand on the Premier League title after Eden Hazard fired them to a 1-0 win at Stamford Bridge.
Raheem Sterling grabbed the headlines on and off the field as Liverpool reignited their Champions League hopes with a 2-0 defeat of 10-man Newcastle.
Louis van Gaal's dream turned into reality as Manchester United put four goals past City in a superb derby win at Old Trafford.
Cesc Fabregas scored an 88th-minute winner as Chelsea restored their seven-point lead at the top of the table with a 1-0 victory at West London rivals QPR.
Aaron Ramsey marked his 150th Premier League appearance with a first half winner as Arsenal closed the gap on leaders Chelsea to four points with a hard-fought 1-0 win at Turf Moor.
Christian Benteke scored his eighth goal in six games to hand Tim Sherwood a winning return to Tottenham and ease Aston Villa's relegation fears.
Playmaker Philippe Coutinho was Liverpool's FA Cup saviour again as his solitary goal beat Blackburn 1-0 to book a Wembley semifinal with Aston Villa.
Manchester City's grip on the Premier League title was loosened further after a controversial Glenn Murray goal put Crystal Palace on the way to a 2-1 victory.
Harry Kane's first outing as captain of Tottenham failed to inspire Spurs in an insipid 0-0 draw at Burnley.
Chelsea responded from conceding a Charlie Adam goal from his own half and losing Diego Costa to a hamstring injury to beat Stoke 2-1 and move seven points clear in the Premier League title race.
Manchester United climbed above their 'noisy neighbours' into third position thanks to a 3-1 win over Aston Villa which included a stunning strike from Wayne Rooney.
Arsenal kept up the pressure at the top of the Premier League as Liverpool were blown away 4-1 at the Emirates Stadium, where Reds contract rebel Raheem Sterling failed to make an impact.
A moment of madness from Liverpool captain Steven Gerrard saw him sent off just 43 seconds after coming on in his final appearance against Manchester United, whose 2-1 victory at Anfield.
Chelsea survived a major scare to secure a 3-2 win at Hull City and restore their six-point lead at the top of the Premier League.
Referee Neil Swarbrick took the gloss off Manchester City's return to winning ways as the Premier League suffered yet another mistaken identity controversy.
Harry Kane's dream week got even better on Saturday as the Tottenham striker followed his first England callup with a maiden Premier League hat trick as embattled Leicester were defeated in a thrilling 4-3 encounter.
Olivier Giroud's first-half double handed Arsenal a sixth successive Premier League victory as they survived a spirited fightback to win 2-1 at Newcastle.
Liverpool maintained the pressure in the race for Champions League qualification as Jordan Henderson's fortunate second-half goal saw off Swansea at the Liberty Stadium to seal a 1-0 win.
Wayne Rooney and Manchester United delivered a knockout performance as Tottenham were blown away at Old Trafford.
Chelsea missed the opportunity to go eight points clear at the top of the Premier League by drawing 1-1 against Southampton.
George Boyd struck a stunning second-half winner as Burnley enhanced their survival hopes by further ravaging Manchester City's fading title quest with a 1-0 victory at Turf Moor.
Marcus Rashford's first half goal made it six wins out of six at Manchester United for caretaker manager Ole Gunnar Solskjaer with a 1-0 win at Tottenham.
Goals from Pedro and Willian earned Chelsea a hard-fought 2-1 win over Newcastle which opened up a six-point gap to fifth-place Arsenal in the battle for a Champions League place.
Liverpool went seven points clear at the top of the Premier League and bounced back from two successive defeats in all competitions after a Mohamed Salah penalty gave them a 1-0 win at Brighton & Hove Albion on Saturday.
Declan Rice scored his first West Ham goal as Arsenal's top four hopes were dented following defeat at the London Stadium
Manchester City scored nine goals without reply, four from Gabriel Jesus, as League One Burton were swept aside 9-0 in the Carabao Cup semifinal first leg at the Etihad Stadium.
A penalty awarded after a VAR review and converted by Harry Kane was enough to give Tottenham a narrow 1-0 lead after the first leg of their Carabao Cup semifinal against Chelsea at Wembley.
Premier League leaders Liverpool paid the price for fielding a weakened side as they were knocked out in the third round of the FA Cup following a 2-1 defeat by Wolverhampton Wanderers on Monday.
Manchester City cruised into the fourth round of the FA Cup with a routine 7-0 victory over Championship strugglers Rotherham at the Etihad.
Joe Willock's two first-half goals sent Arsenal on their way to an easy 3-0 win against Blackpool in the FA Cup third round on Saturday night.
Tottenham's Fernando Llorente scored a hat trick as they chalked up their record competitive away win with a 7-0 thrashing of fourth-tier Tranmere Rovers in the opening game of the FA Cup third round at Prenton Park on Friday.
Leroy Sane struck the winner as Manchester City beat Liverpool 2-1 in a gripping Premier League clash on Thursday, inflicting the first loss of the season on Jurgen Klopp's side and cutting their lead at the top to four points.
Ole Gunnar Solskjaer's Midas touch at Manchester United continued at St James' Park as goals from Romelu Lukaku and Marcus Rashford earned the caretaker manager a fourth successive win on Wednesday.
Chelsea struggled to break down a resolute Southampton as both sides settled for a 0-0 Premier League draw at Stamford Bridge on Wednesday.
helsea have signed Christian Pulisic from Borussia Dortmund for €64 million and have loaned the United States international back to the Bundesliga club ahead of him moving to the Premier League in the summer.
Arsenal returned to winning ways on Tuesday with a 4-1 victory over struggling Fulham at the Emirates Stadium that moves them within two points of fourth-placed Chelsea.
Tottenham moved back into second place in the Premier League, six points behind leaders Liverpool, after cruising to a 3-0 win at lowly Cardiff City on Tuesday.
Eden Hazard took his goal tally for Chelsea to triple figures, scoring twice in a 2-1 win at Watford on Wednesday as the Blues stayed fourth in the Premier League.
Brighton & Hove Albion came from a goal down to draw 1-1 with Arsenal in the Premier League on Wednesday and arrest a run of three straight defeats.
Liverpool treated their fans to some Christmas cheer with a 4-0 thrashing of Newcastle United at Anfield on Wednesday, extending their lead at the top of the table.
Manchester City slumped to a shock 2-1 defeat by Leicester City on Wednesday as Ricardo Pereira's superb late strike condemned the champions to a second successive Premier League loss.
Ole Gunnar Solskjaer continued his dream start as Manchester United caretaker manager with a 3-1 Premier League win over Huddersfield on his Old Trafford debut in the dugout on Wednesday.
Tottenham Hotspur delivered a Boxing Day knockout to Bournemouth with a 5-0 win in the Premier League on Wednesday to move them up to second in the standings.
Tottenham moved to within two points of second place Manchester City after coming from behind to earn a 6-2 victory at Everton.
Ole Gunnar Solskjaer enjoyed the perfect start to life as Manchester United manager with an emphatic 5-1 victory away at former club Cardiff -- the first time they had scored five since Sir Alex Ferguson's last match in charge in 2013.
Jamie Vardy's well-taken breakaway goal earned Leicester a 1-0 win at Chelsea on Saturday to ease the pressure on coach Claude Puel and inflict the hosts' first home Premier League defeat of the season.
Pierre-Emerick Aubameyang scored twice to go to the top of the Premier League scoring charts as Arsenal beat Burnley 3-1.
Liverpool will spend Christmas on top of the Premier League after goals from Mohamed Salah and Virgil van Dijk earned them a 2-0 win at Wolves on Friday, opening up a four-point lead over second-placed Manchester City.
An 84th-minute Eden Hazard goal, that spun into the net after a heavy deflection, earned Chelsea a place in the Carabao Cup semifinals after a 1-0 win over Bournemouth in an entertaining tie on Wednesday.
Tottenham's Dele Alli was hit in the back of the head with what appeared to be a plastic bottle during his side's 2-0 win over Arsenal in the Carabao Cup quarterfinals at the Emirates Stadium on Wednesday.