Monaco earned the first point of their disappointing Champions League campaign on Wednesday in their first European outing under Thierry Henry but their 1-1 draw at Club Brugge still left both sides with little chance of making the knockout stages.
Captain Luuk de Jong struck a late equaliser for PSV Eindhoven as they drew 2-2 with Tottenham Hotspur on Wednesday, a result that did little for either side's Champions League ambitions.
An impressive Juventus beat Manchester United 1-0 at Old Trafford on Tuesday to take command of Champions League Group H with a maximum nine points from three games and demonstrate just how far Jose Mourinho's side are from Europe's elite.
Manchester City began to pull their weight like proper Champions League heavyweights when they became the first English team to win at Shakhtar Donetsk in European competition with a 3-0 win in their group F match in Kharkiv on Tuesday.
Hoffenheim's Joelinton scored in stoppage time to give the German club a dramatic 3-3 draw against Olympique Lyon in a rollecoaster Champions League Group F match on Tuesday.
AS Roma's Edin Dzeko drew level with Barcelona's Lionel Messi at the top of this season's Champions League scoring charts as the Italians set the pace in Group G with a 3-0 win over CSKA Moscow at the Stadio Olimpico on Tuesday.
Real Madrid held onto a 2-1 win over Viktoria Plzen in Champions League Group G action on Tuesday.
Noussair Mazraoui scored an injury-time winner as Ajax claimed what could be a vital 1-0 win over Benfica in their Champions League Group E clash at the Johan Cruyff Arena on Tuesday.
Champions League debutants Young Boys scored their first goal and picked up their first ever point in the competition with a deserved 1-1 draw at home to Valencia on Tuesday.
Bayern Munich scored twice in two minutes to beat hosts AEK Athens 2-0 on Tuesday to continue their recovery from a recent dip in form and climb to the top of their Champions League Group E.
Lorenzo Insigne's late winner gave Napoli a deserved 1-0 Champions League victory over Liverpool on Wednesday that saw the Italians move to the top of Group C.
Mauro Icardi took advantage of an error from PSV Eindhoven goalkeeper Jeroen Zoet to gift Inter Milan a 2-1 victory in their Champions League Group B clash on Wednesday.
Borussia Dortmund's blistering start to the season under manager Lucien Favre gathered momentum as the Bundesliga leaders consigned ailing Monaco to a 3-0 defeat in the Champions League on Wednesday.
Antoine Griezmann had a goal in each half -- including the 8,000th Champions League goal -- and Koke also scored in added time to lead Atletico Madrid to a 3-1 win over Club Brugge on Wednesday.
A second-half header by Moussa Marega gave Porto a 1-0 Champions League win over Galatasaray at home on Wednesday.
Lionel Messi scored twice and powered Barcelona to a 4-2 win against Tottenham in Champions League Group B at Wembley Stadium on Wednesday night.
United States international Weston McKennie's late header gave Schalke a 1-0 win over Lokomotiv Moscow in the Champions League on Wednesday as they continued to recover from a poor start to the season.
Neymar scored his second Champions League hat trick as Paris Saint-Germain rolled to a 6-1 victory over Red Star Belgrade in a Champions League group-stage game at the Parc des Princes on Wednesday.
Roma's Edin Dzeko was again the tormentor for Viktoria Plzen as he scored a hat trick in a 5-0 Champions League Group G win for the Italian side on Tuesday.
Manchester United's dismal run of form continued as they were held to a 0-0 draw by Valencia in a drab Champions League clash at Old Trafford.
Lyon produced a stirring fightback to claw back two superb goals from Shakhtar Donetsk's Junior Moraes and rescue a 2-2 draw behind closed doors in a thrilling end-to-end contest at their Groupama Stadium on Tuesday.
A depleted Real Madrid suffered a shock 1-0 Champions League defeat at CSKA Moscow on Tuesday, extending a poor run of form for the holders that has left them without a win in three games.
Benfica played the entire second half with 10 men and squandered a two-goal lead before claiming a thrilling 3-2 win away to AEK Athens in Champions League Group E action on Tuesday.
Full-back Noussair Mazraoui earned a youthful Ajax side a 1-1 draw at misfiring Bayern Munich in their Champions League Group E clash at the Allianz Arena on Tuesday.
Paulo Dybala hit a hat-trick as Juventus maintained their 100% record in the Champions League courtesy of a 3-0 win against BSC Young Boys.
David Silva nipped in to secure a late 2-1 victory for Premier League champions Manchester City at Hoffenheim.
Cristiano Ronaldo's Champions League debut for Juventus lasted only 29 minutes as he was red-carded but the Italians began their Group H campaign impressively with a 2-0 victory at Valencia on Wednesday.
Paul Pogba scored two first-half goals as Manchester United spoiled Young Boys' first appearance in the group stage of the Champions League by cruising to a comfortable 3-0 victory at the Stade de Suisse on Wednesday.
Manchester City looked far from potential Champions League winners as they fell to a surprise 2-1 loss at home to Olympique Lyonnais on Wednesday with a flat performance that leaves them with plenty of work to do to progress from Group F.
CSKA Moscow salvaged a 2-2 draw with Viktoria Plzen in the Champions League on Wednesday after a penalty deep in stoppage time.
Late goals by central defenders Jose Gimenez and Diego Godin earned Atletico Madrid a 2-0 victory over Juventus in their Champions League round-of-16 first leg at the Wanda Metropolitano, amid more video assistant referee (VAR) controversy.
Late goals from Leroy Sane and Raheem Sterling gave Manchester City a 3-2 win at Schalke 04 in their Champions League round of 16 first leg on Wednesday that put the English side in the driving seat.
Liverpool and Bayern Munich cancelled each other out to draw 0-0 in the first leg of their Champions League round-of-16 clash on a tense night at Anfield.
Barcelona were held to a frustrating 0-0 draw at Olympique Lyonnais in their Champions League last-16 first leg on Tuesday as both sides remained unbeaten in this season's competition.
Marco Asensio scored a late winner for Real Madrid in a 2-1 victory at Ajax Amsterdam, who were left to rue a goal disallowed by the video assistant referee (VAR) in their Champions League round-of-16 first leg on Wednesday.
Tottenham Hotspur will take a commanding lead to the Westfalenstadion next month after beating Borussia Dortmund 3-0 in the first leg of their Champions League round-of-16 clash at Wembley.
Goals from Presnel Kimpembe and Kylian Mbappe left Manchester United with a mountain to climb as Paris Saint-Germain won 2-0 at Old Trafford in the Champions League round-of-16 first leg and Paul Pogba was sent off.
Teenager Nicolo Zaniolo scored a quick-fire double to earn AS Roma a 2-1 win against Porto in their Champions League last-16 first leg on Tuesday.
Manchester United will face Paris Saint-Germain in the Champions League round of 16, while Liverpool have been drawn against Bayern Munich.
Manchester City battled back to winning ways, coming from a goal down to overwhelm Hoffenheim 2-1 in the Champions League with a brilliant Leroy Sane double that ensured they progressed to the last-16 as winners of Group F on Wednesday.
Manchester United endured an undignified end to their topsy-turvy Champions League group stage campaign by losing 2-1 at already-eliminated Valencia on Wednesday and missing their chance of topping Group H.
Olympique Lyonnais earned the point they required to book their place in the Champions League last 16 but needed Nabil Fekir's equaliser 20 minutes into the second half to salvage a 1-1 draw away to Shakhtar Donetsk.
Two goals from striker Guillaume Hoarau led Young Boys to a shock 2-1 Champions League win over already-qualified Juventus on Wednesday to hand the Serie A side their first away defeat in a competitive match for over a year.
Striker Robert Lewandowski scored twice as Bayern Munich sealed top spot in Group E following a thrilling 3-3 Champions League draw at Ajax in which both sides ended with 10 men.
Benfica finished its Champions League campaign with a 1-0 win over AEK Athens on Wednesday.
Real Madrid suffered their heaviest ever home defeat in Europe on Wednesday when the already-qualified Spaniards were thumped 3-0 at the Santiago Bernabeu by CSKA Moscow in the Champions League.
Viktoria Plzen beat struggling Roma 2-1 in the Champions League on Wednesday to earn a Europa League spot.
Tottenham Hotspur made it into the round of 16 of the Champions League, coming from behind to grab a 1-1 draw at Barcelona on Tuesday which saw them finish second in Group B at the expense of Inter Milan.
Paris Saint-Germain reached the round of 16 of the Champions League on Tuesday thanks to an inspired performance by their three-pronged attack of Neymar, Edinson Cavani and Kylian Mbappe in a 4-1 win at Red Star Belgrade.
Inter Milan were knocked out of the Champions League after they could only manage a 1-1 draw at home to Group B's bottom club PSV Eindhoven on Tuesday to finish third behind Tottenham Hotspur.
Mohamed Salah's first-half strike gave Liverpool a 1-0 win over Napoli in Champions League Group C action on Tuesday.
An under-strength Borussia Dortmund deepened AS Monaco's season-long misery on Tuesday with a 2-0 away victory that ensured they finished top of Champions League Group A ahead of Atletico Madrid.
Atletico Madrid were denied top place in Group A of the Champions League on Tuesday after a goalless draw away at Club Brugge in Belgium meant they finished second behind Borussia Dortmund.
Alessandro Schoepf's stoppage time goal gave Schalke 04 a 1-0 win over Lokomotiv Moscow in Champions League Group D action on Tuesday.
Porto struggled to a 3-2 away victory over Galatasaray in their final Champions League group match on Tuesday but the Turks stayed third in Group D and secured a spot in the Europa League's round of 32.
Real Madrid midfielder Luka Modric has ended the Cristiano Ronaldo-Lionel Messi stranglehold on the Ballon d'Or.
Two first-half goals gave Paris Saint-Germain a crucial 2-1 Champions League home win over Liverpool, putting them in a great position to qualify and leaving Jurgen Klopp's side, finalists last season, in danger of elimination.
Napoli swept aside Red Star Belgrade with a typically entertaining performance as two goals from Dries Mertens helped them to a 3-1 win over the former European champions in their Champions League match on Wednesday.
Borussia Dortmund booked their spot in the Champions League knockout stage with a game to spare after a goalless draw against visitors Club Brugge in Group A on Wednesday.
Christian Eriksen kept Tottenham Hotspur's hopes of reaching the round of 16 in the Champions League alive when he came off the bench to score a late winner in his side's 1-0 victory over Inter Milan at Wembley on Wednesday.