Dnipro advanced to their first European final after Yevhen Seleznyov's second-half header gave them a 2-1 aggregate win over Napoli in the Europa League.
Holders Sevilla stormed through to the Europa League final after completing a semifinal mauling of Fiorentina in Florence.
Sevilla remain firmly on course to retain their Europa League title after earning a 3-0 lead from the home leg of their semifinal with Fiorentina.
Napoli have it all to do to reach the Europa League final after Dnipro hit them with a sucker-punch equaliser to draw the first leg of their semifinal 1-1 in Italy.
Reigning Europa League holders Sevilla will face Serie A side Fiorentina in the semifinals of this season's competition while Dnipro Dnipropetrovsk were drawn against Napoli.
Sevilla progressed to the semifinals of the Europa League after Kevin Gameiro's goal five minutes from time settled a thrilling tie with Zenit St Petersburg.
Mario Gomez and Juan Manuel Vargas got the goals as Fiorentina made sure of a place in the Europa League semifinals.
Napoli advanced to the Europa League semifinals on Thursday evening, with a 2-2 draw against Wolfsburg seeing Rafael Benitez's side progress 6-3 on aggregate.
Club Brugge's record 11-match unbeaten run in the Europa League came to an end in their quarterfinal second leg, as Dnipro sealed their progress with a 1-0 win at the NSK Olimpiyskyi stadium.
Rafael Benitez's Napoli all but booked their place in the Europa League semifinals with a stunning 4-1 win over Wolfsburg in Germany on Thursday night.
A glorious late strike from Denis Suarez helped Sevilla come from behind to beat Zenit St Petersburg 2-1 in the first leg of their Europa League quarter-final in Spain.
Club Brugge were held to a goalless draw against Dnipro in their Europa League quarterfinal first leg encounter at the Jan Breydel Stadion on Thursday.
Substitute Khouma Babacar's goal in stoppage-time gave Fiorentina a 1-1 draw and a crucial away goal in their Europa League quarter-final first leg against Dynamo Kiev.
Wolfsburg and Napoli are to meet in the quarterfinals of the Europa League following Friday's draw for the last eight.
Everton crashed out of the Europa League after being punished for poor defending by a ruthless Dynamo Kiev side in Ukraine.
Brilliant Fiorentina stunned Roma with an early goal blitz to seal their spot in the Europa League quarterfinals at the expense of their Italian rivals.
Wolfsburg progressed to the last eight of the Europa League with a 2-1 second-leg victory away to Roberto Mancini's Inter Milan.
Sevilla remain on course to retain their Europa League title after easing past Spanish rivals Villarreal to reach the quarterfinals.
Napoli are through to the quarterfinals of the Europa League after a hard-fought goalless draw against Dinamo Moscow in Russia.
Zenit St Petersburg booked their place in the Europa League quarterfinals despite going down 1-0 to a late headed goal from Torino's Kamil Glik at the Stadio Olimpico.
Yevhen Konoplyanka's extra-time strike booked Dnipro's place in the quarter-finals of the Europa League on away goals despite a 2-1 second-leg defeat to Ajax in Amsterdam.
Vitolo scored the fastest goal in Europa League history as holders Sevilla took a giant step towards the quarter-finals with a 3-1 away victory over Spanish rivals Villarreal.
Roma rallied after falling behind to an early Josip Ilicic goal to draw 1-1 with Fiorentina in their Europa League last-16 tie at Stadio Artemio Franchi.
Gonzalo Higuain plundered a hat trick as Napoli recovered from an early fright to seize a commanding advantage against 10-man Dinamo Moscow in the Europa League.
Everton once again produced a Europa League performance in contrast to their domestic displays as Romelu Lukaku's late penalty secured them a 2-1 come-from-behind victory in their last-16 first leg against Dynamo Kiev.
Kevin De Bruyne inspired Wolfsburg to a 3-1 win over Inter Milan to put the Germans in control of their Europa League last-16 tie.
Dnipro claimed a deserved win over Ajax from the first leg of their Europa League last-16 tie in Kiev, but may rue not building a bigger advantage to take to Amsterdam.
Zenit St Petersburg took a big step towards the Europa League quarterfinals with a 2-0 win over 10-man Torino in the first leg of their last-16 clash.
Everton will face Dynamo Kiev in the last 16 of the Europa League while holders Sevilla were drawn against fellow Spaniards Villarreal.
Liverpool lost their first European penalty shoot-out as Dejan Lovren was the only man to miss from the spot against Besiktas in Istanbul.
Arsenal will face Belarusian side BATE Borisov in the Europa League round of 32, while Chelsea have been drawn against Sweden's Malmo.
Alexandre Lacazette's first-half goal gave Arsenal a 1-0 win over FK Qarabag in Europa League Group E action on Thursday.
Olympiakos pulled off a stunning 3-1 Europa League win over AC Milan that put them into the round of 32 and sent the Italians crashing out as the remaining places in the knockout stage were decided on Thursday.
Table-toppers Chelsea drew 2-2 at Vidi in their final Group L in the Europa League on Thursday.
Chelsea made it five wins in five tries in the Europa League with a convincing 4-0 win against 10-man PAOK at Stamford Bridge on Thursday.
Arsenal maintained their three-point lead atop Europa League Group E on Thursday with a 3-0 win against Vorskla.
AC Milan came from behind before stepping on the gas to pull away from F91 Dudelange for a 5-2 Europa League win on Thursday.
Arsenal qualified for the Europa League knockout stage with a 0-0 draw against Sporting at The Emirates, although striker Danny Welbeck was carried off on a stretcher in the first half with a serious ankle injury.
AC Milan and Real Betis took a step towards qualifying for the Europa League knockout stage with a 1-1 draw in Group F on Thursday.
Olivier Giroud ended his drought by scoring the only goal as Chelsea won 1-0 at BATE Borisov on Thursday to clinch a place in the knockout stage of the Europa League with two group games to spare.
Arsenal and Chelsea were among seven teams to reach the Europa League knockout stage on Thursday, while last year's runners-up Olympique de Marseille were eliminated at the group phase.
Ruben Loftus-Cheek scored three goals as Chelsea dispatched BATE Borisov 3-1 in Europa League action on Thursday.
Real Betis stunned AC Milan with a 2-1 win at the San Siro in Europa League group play on Thursday.
Danny Welbeck's goal in the 77th minute was enough for Arsenal to get a 1-0 win over Sporting CP in Europa League action on Thursday.
Sevilla suffered a shock defeat by Russians Krasnodar, going down 2-1 in Europa League Group J.
Ten-man Celtic threw away an early lead to succumb to a 3-1 defeat to Red Bull Salzburg in Austria.
Alvaro Morata provided the lone goal in Chelsea's 1-0 win over Vidi in Europa League group-stage action on Thursday.
Emile Smith Rowe scored his first career goal in Arsenal's 3-0 win over FK Qarabag in Europa League group-stage action on Thursday.
Substitute Patrick Cutrone netted twice in nine minutes to lift AC Milan to a 3-1 comeback win at home to Olympiakos in Europa League group-stage action.
Arsenal's superb form continued into the Europa League as they thrashed Ukrainian side Vorksla Poltava 4-2 on Thursday.
Gonzalo Higuain's deflected effort in the 59th minute sealed a 1-0 victory for AC Milan over Luxembourg side F91 Dudelange on Thursday night in Europa League action.
Chelsea's Europa League campaign kicked off in style with a 1-0 win at PAOK Salonika on Thursday.
Leigh Griffiths made the difference for Celtic in their Europa League opener, coming off the bench to score a late winner against Rosenborg.
Burnley's European adventure came to an end on Friday as the Premier League side crashed out of the Europa League playoff round with a 1-1 draw against Olympiakos.
Celtic were held to a 1-1 draw by Lithuanian side Suduva Marijampole in the first leg of their Europa League play-off at the ARVI Futbolo Arena.
Antoine Griezmann struck twice as Atletico Madrid powered past Marseille to lift their third Europa League title in nine years.
Atletico Madrid advanced to the Europe League final 2-1 on aggregate after a 1-0 victory over Arsenal at the Wanda Metropolitano on Thursday.
Marseille scored a dramatic extra-time decider against Red Bull Salzburg to earn a Europa League final showdown with Atletico Madrid in Lyon on May 16.
If Arsene Wenger's Arsenal finale is to be a Europa League final in Lyon his side will have to do it the hard way after surrendering a well-deserved lead to draw against 10-man Atletico Madrid in the first leg of their semi-final.
Florian Thauvin put Marseille within touching distance of a place in the UEFA Europa League final with a controversial opener as his side beat Red Bull Salzburg 2-0 at the Stade Velodrome.