Ligue 1 side Monaco recorded a 3-1 victory over Young Boys in the first leg of their Champions League third qualifying round tie on Tuesday night.
All of the game's goals came in the second half in Bern, Switzerland, with Layvin Kurzawa opening the scoring on 64 minutes.
Guido Carrillo doubled Monaco's lead, Raphael Nuzzolo pulled a goal back for Young Boys before Mario Pasalic netted a minute later to wrap up the away victory.
Fenerbahce's tie with Shakthar Donetsk is delicately balanced after neither side could find a breakthrough as their match ended 0-0 in Istanbul.
Former Manchester United striker Robin van Persie was sent on as a second-half substitute for Fener, while Nani played the full 90 minutes.
Sparta Prague battled for a 2-2 draw in their meeting at CSKA Moscow, with Alan Dzagoev opening the scoring for the hosts.
Kehinde Fatai hit back in the 15th minute, Zoran Tosic restored CSKA's advantage but Ladislav Krejci salvaged an away draw for Sparta Prague.
A penalty from Nikos Karelis clinched a 2-1 win for Panathinaikos against Club Brugge.
Boli Bolingoli-Mbombo put the Belgian outfit 1-0 up in Greece only for Marcus Berg to hit back and then Karelis to convert from the penalty spot.
Apoel Nicosia overcame FC Midtjylland 2-1, Viktoria Plzen defeated Maccabi Tel-Aviv by the same score while Skenderbeu Korce triumphed 2-0 at FC Milsami.
BATE Borisov were denied an away success as Paulo Vinicius scored in the 89th minute for Videoton FC Fehervar after Aleksandr Karnitskiy had struck in the 56th minute of a 1-1 stalemate.
Elsewhere, Dinamo Zagreb drew 1-1 with Molde as the hosts at Stadion Maksimir finished the match with 10 men.
Angelo Henriquez put Dinamo Zagreb 1-0 up before Ola Kamara restored parity. Paulo Machado was sent off in the second half.