Barcelona extended their 100 percent start in La Liga as substitute Paulinho's late strike secured a 2-1 come-from-behind victory at Getafe.
Bayern Munich got back to winning ways in the Bundesliga after easing to a 4-0 victory over Mainz.
Arsenal came from behind to beat Cologne in their delayed Europa League opener against a backdrop of crowd trouble at the Emirates Stadium.
Everton produced another hugely disappointing display as they were beaten 3-0 by Atalanta in their Europa League Group E opener in Reggio Emilia.
Andre Silva scored a hat trick as AC Milan eased to a 5-1 victory over Austria Vienna in their Europa League group-stage opener.
Harry Kane lifted Tottenham's Wembley curse by scoring twice and firing his side to an opening Champions League win over Borussia Dortmund.
Manchester City produced an outstanding performance to open their seventh successive Champions League campaign with an emphatic 4-0 win at Feyenoord.
Liverpool's Champions League return did not go entirely to plan as they repeatedly shot themselves in the foot in the 2-2 draw at home to Sevilla.
Last season's semifinalist Monaco were held 1-1 by upstarts RB Leipzig at Red Bull Arena in the clubs' Group G opener.
Shakhtar Donetsk stunned Napoli 2-1 at Metalist Stadium thanks to goals from Taison and Facundo Ferreyra.
Besiktas started their Champions League Group G campaign with a 3-1 win against Porto at the Estadio do Dragao.
Maribor and Spartak Moscow played out a 1-1 draw in their Champions League Group E opener as a referee narrowly escaped being hit by a flare.
Cristiano Ronaldo scored twice to help Real Madrid open their Champions League campaign with a 3-0 win over Apoel on Wednesday.
Lionel Messi summoned another mesmerising performance as Barcelona breezed to a 3-0 win over Juventus in their UEFA Champions League Group D opener at the Camp Nou.
Chelsea marked their Champions League return with a 6-0 Group C rout of Azerbaijan's Qarabag, but sterner tests await.
Free-spending Paris St Germain demonstrated their prowess with a 5-0 thumping of Celtic in their Champions League opener at Parkhead.
Saul Niguez squandered a gilt-edged chance to snatch Champions League victory at the death as Atletico Madrid had to make do with a goalless draw against Roma.
CSKA Moscow forward Timur Zhamaletdinov made a memorable Champions League debut on Tuesday by scoring the winner in a 2-1 comeback victory at Benfica in Group A.
Five-time champions Bayern Munich opened their Champions League campaign with a flattering 3-0 win over 10-man Anderlecht on Tuesday.
Olympiakos conceded a goal after just 69 seconds of their Champions League campaign and went on to lose 3-2 to Sporting Lisbon at home in Group D on Tuesday.
Manchester United eased back into Champions League life as Marouane Fellaini, Romelu Lukaku and Marcus Rashford put Basle to the sword.
Barcelona and Juventus will renew their recent rivalry when they meet at the Camp Nou in the group stage of the UEFA Champions League on Tuesday.
Real Sociedad made it three wins from their opening three La Liga games as they beat Deportivo La Coruna 4-2 at the Riazor.
Lyon have climbed to third in Ligue 1 after a 2-1 home defeat of Guingamp.
Schalke bounced back from defeat to Hannover in their last outing as they wrapped up a 3-1 victory over Stuttgart at the Veltins-Arena.
Ciro Immobile scored a hat trick as AC Milan's new-look side were humbled 4-1 by Lazio at the Stadio Olimpico in a game delayed for an hour by torrential rain.
Inter Milan extended their 100 per cent start to the season as Mauro Icardi's penalty and a superb Ivan Perisic volley steered them to a 2-0 home win over SPAL.
Newcastle gave absent manager Rafael Benitez the perfect pick-me-up with a 1-0 victory at Swansea.
Frank de Boer's short reign at Crystal Palace was plunged into further turmoil after an early blunder from Lee Chung-Yong brought their fourth straight Premier League defeat.
Lionel Messi plundered a hat trick and substitute Ousmane Dembele came off the bench to set up a late goal for Luis Suarez as Barcelona romped to a 5-0 win in the Catalan derby against Espanyol at the Camp Nou.
The round of 16 draw for the Champions League has just concluded, and it's all smiles if you're a club from the North West of England as Manchester City are the new favourites.
Cristiano Ronaldo scored from a free kick to help Real Madrid beat Gremio 1-0 and claim the Club World Cup in Saturday's final in Abu Dhabi.
Gareth Bale was the surprise hero as Real Madrid survived a shock against outsiders Al Jazira to win 2-1 in Wednesday's extra dramatic Club World Cup semifinal in Abu Dhabi.
Reigning champions Real Madrid will face Paris Saint-Germain in the Champions League round of 16, while Chelsea take on Barcelona.
Real Madrid star Cristiano Ronaldo won the fifth Ballon d'Or of his career on Thursday, matching Lionel Messi as the most-awarded winner of one of the sport's top individual honours.
A scintillating display of football from Liverpool's Fab Four saw Jurgen Klopp's side blaze their way into the Champions League knockout phase with a 7-0 victory over Spartak Moscow.
Manchester City slumped to their first defeat of the season with a 2-1 loss to Shakhtar Donetsk in their final Champions League Group F game.
Fernando Llorente and Georges-Kevin Nkoudou scored their first goals for Tottenham goal as Spurs strolled into the Champions League round of 16 by beating Apoel Nicosia.
Cristiano Ronaldo became the first player to score in every Champions League group stage match as Real Madrid beat Borussia Dortmund 3-2 at the Bernabeu.
Feyenoord finally secured their first points in Champions League Group F, rallying from a goal down to beat Napoli 2-1 on Wednesday, costing the Serie A side a spot in the round of 16.
Sevilla qualified for the round of 16 of the Champions League with a 1-1 draw at Maribor on Wednesday.
Ten-man Porto advanced out of Group G with a 5-2 defeat of a disappointing Monaco side, who also went down a man at the Estadio do Dragao.
RB Leipzig's Champions League debut ended in a 2-1 home loss to Group G winner Besiktas on Wednesday.
Bayern Munich got a little payback against Paris Saint-Germain with a 3-1 win at the Allianz Arena on Tuesday night in Group B.
Juventus secured their place in the round of 16 of the Champions League with a 2-0 victory against Olympiakos in Greece.
Barcelona completed their Champions League Group D campaign with a 2-0 win over Sporting Lisbon at the Camp Nou.
Manchester United came from behind to beat CSKA Moscow and top their Champions League group as Jose Mourinho's men took their unbeaten home run to a club record-equalling 40th match.
Chelsea missed a chance to finish top of Champions League Group C after a 1-1 draw at home to Atletico Madrid, who will settle for a Europa League spot.
Roma progressed to the Champions League knockout stage as Group C winners after beating Qarabag 1-0 on Tuesday.
Celtic will be playing European football after Christmas despite a 1-0 Champions League defeat by Anderlecht at Parkhead.
Lionel Messi started on the bench as Barcelona secured their passage into the round of 16 of the Champions League with a 0-0 draw at Juventus.
Corentin Tolisso set up one goal and scored another to give Bayern Munich a 2-1 win over Anderlecht on Wednesday in Group B of the Champions League.
Manchester United were denied a place in the Champions League knockout phase as Michael Lang's late strike secured Basel a memorable, and deserved, victory.
Willian scored twice and was fouled for two penalties as Chelsea cruised into the Champions League knockout stages with a 4-0 win over 10-man Qarabag at the Olympic Stadium in Baku.
Antoine Griezmann's stunning goal kept Atletico Madrid's Champions League hopes alive as they grabbed a vital victory over Roma.
Celtic suffered another night of European anguish against Paris St Germain in a 7-1 thrashing in the Parc des Princes.
Raheem Sterling struck a late winner as Manchester City secured top spot in Champions League Group F with a 1-0 win over Feyenoord.
Cristiano Ronaldo set another Champions League record as holders Real Madrid sealed their place in the knockout stages with a comprehensive victory against Apoel Nicosia.
Lorenzo Insigne's magical strike broke Shakhtar Donetsk's defences and Napoli went on to a 3-0 win, which gives them hope of Champions League progress.
Liverpool squandered a three-goal half-time lead to throw away the chance of early Champions League qualification as Sevilla netted a 93rd-minute equaliser in Spain.