Girona claimed a stunning 2-1 victory over Real Madrid to deal a major blow to the La Liga champions' hopes of retaining their title.
New boss Claude Puel began his Leicester reign with a routine win over managerless Everton as the Foxes eased away from trouble.
Lyon moved within seven points leaders Paris Saint-Germain with a comfortable 2-0 victory over bottom club Metz, whose losing run was extended to five Ligue 1 matches.
Lionel Messi and Paulinho hit the target as Barcelona crept past Athletic Bilbao to maintain their four-point lead in La Liga.
A sensational Stephan El Shaarawy volley proved the difference as Roma narrowly beat Bologna 1-0 in an entertaining match.
Eden Hazard's first Premier League goal of the season eased Chelsea past Bournemouth 1-0 at Dean Court.
Bayern Munich swept aside 10-man RB Leipzig for the second time in a week to land an important blow in the race for the Bundesliga title.
Gonzalo Higuain fired a brilliant double as Juventus won 2-0 at AC Milan to draw level on points with Napoli at the top of Serie A.
Keita Balde and Thomas Lemar fired second-half goals as Monaco won 2-0 at Bordeaux to stay in touch with Ligue 1 leaders Paris St Germain.
Leaders Manchester City strolled past West Brom to maintain their grip at the top of the Premier League.
Liverpool manager Jurgen Klopp got one over on best friend David Wagner as Daniel Sturridge's 100th club goal paved the way for a 3-0 win over Huddersfield at Anfield.
Arsenal came from behind to beat Swansea in Arsene Wenger's 800th Premier League game in charge of the Gunners.
Bundesliga leaders Borussia Dortmund suffered their second defeat of the season as Hannover won a thrilling contest 4-2 at the HDI-Arena.
Atletico Madrid are still undefeated and in fourth place in La Liga after notching their fifth draw, a disappointing 1-1 result at home versus Villarreal.
Valencia extended their winning streak to seven matches to stay on Barcelona's heels at the top of La Liga with a 2-1 victory at Alaves.
Anthony Martial came off the bench to score the winning goal as Manchester United beat Tottenham 1-0 at Old Trafford.
Real Madrid needed two second-half penalties to secure a 2-0 win over third-tier side Fuenlabrada in their first outing in this season's Copa del Rey
AC Milan ended a run of four Serie A games without victory as they beat Chievo 4-1.
Juventus kept up their pursuit of Inter Milan and Napoli at the top of Serie A with a 4-1 win against Spal.
West Ham eased the pressure on manager Slaven Bilic by fighting back from two goals down to beat Tottenham 3-2 in the Carabao Cup fourth round.
David Unsworth's first match as Everton's caretaker manager ended in a 2-1 defeat at Chelsea in the fourth round of the Carabao Cup.
Bayern Munich needed penalties to see off RB Leipzig in the DFB Pokal second round on Wednesday after the match finished 1-1 after 120 minutes of regular and extra time.
Gerard Deulofeu had a goal and an assist and Jose Arnaiz scored on his senior debut as Barcelona secured a comfortable 3-0 win in the first leg of their Copa del Rey tie against Real Murcia at Estadio Nueva Condomina.
Claudio Bravo was the hero as stuttering Manchester City needed penalties to see off hard-working Wolves and make the Carabao Cup quarterfinals.
Bundesliga leaders Borussia Dortmund made light work of FC Magdeburg as they cruised past the third tier side 5-0 in their German Cup second round tie on Tuesday.
Inter Milan went top of Serie A after holding on for a 3-2 win against Sampdoria at the San Siro.
Teenage striker Eddie Nketiah came off the bench to score twice on his home debut and send Arsenal into the quarter-finals of the Carabao Cup at the expense of Norwich.
Manchester United bounced back from their Huddersfield horror show with a comfortable Carabao Cup victory at Swansea.
Gianluigi Buffon, Neymar and Leonardo Bonucci are the new names in the 2017 FIFPro World 11, joining the likes of Lionel Messi and Cristiano Ronaldo.
Real Madrid star Cristiano Ronaldo has beaten Lionel Messi and Neymar to win The Best FIFA Men's Player award for the second year running.
Bayern Munich look assured of a Champions League quarterfinal spot for a seventh straight season after thrashing 10-man Besiktas 5-0 in Germany.
Lionel Messi broke his goal duck against Chelsea to deny Antonio Conte's side a crucial lead over Barcelona in their Champions League showdown.
Sadio Mane scored a hat trick and Mohamed Salah continued his phenomenal run with a 30th goal of the season as Liverpool won 5-0 at Porto to virtually assure themselves a Champions League quarterfinal place.
Cristiano Ronaldo scored twice and Marcelo got another as Real Madrid came from a goal down to take a 3-1 lead over Paris Saint-Germain in the first leg of their Champions League clash at the Bernabeu.
Ilkay Gundogan scored twice as Manchester City put one foot in the Champions League quarterfinals with an emphatic 4-0 win over Basel.
Christian Eriksen completed a remarkable Tottenham comeback as they rallied from two down to draw with Juventus in the Champions League last 16.
The round of 16 draw for the Champions League has just concluded, and it's all smiles if you're a club from the North West of England as Manchester City are the new favourites.
Cristiano Ronaldo scored from a free kick to help Real Madrid beat Gremio 1-0 and claim the Club World Cup in Saturday's final in Abu Dhabi.
Gareth Bale was the surprise hero as Real Madrid survived a shock against outsiders Al Jazira to win 2-1 in Wednesday's extra dramatic Club World Cup semifinal in Abu Dhabi.
Reigning champions Real Madrid will face Paris Saint-Germain in the Champions League round of 16, while Chelsea take on Barcelona.
Real Madrid star Cristiano Ronaldo won the fifth Ballon d'Or of his career on Thursday, matching Lionel Messi as the most-awarded winner of one of the sport's top individual honours.
A scintillating display of football from Liverpool's Fab Four saw Jurgen Klopp's side blaze their way into the Champions League knockout phase with a 7-0 victory over Spartak Moscow.
Manchester City slumped to their first defeat of the season with a 2-1 loss to Shakhtar Donetsk in their final Champions League Group F game.
Fernando Llorente and Georges-Kevin Nkoudou scored their first goals for Tottenham goal as Spurs strolled into the Champions League round of 16 by beating Apoel Nicosia.
Cristiano Ronaldo became the first player to score in every Champions League group stage match as Real Madrid beat Borussia Dortmund 3-2 at the Bernabeu.
Feyenoord finally secured their first points in Champions League Group F, rallying from a goal down to beat Napoli 2-1 on Wednesday, costing the Serie A side a spot in the round of 16.
Sevilla qualified for the round of 16 of the Champions League with a 1-1 draw at Maribor on Wednesday.
Ten-man Porto advanced out of Group G with a 5-2 defeat of a disappointing Monaco side, who also went down a man at the Estadio do Dragao.
RB Leipzig's Champions League debut ended in a 2-1 home loss to Group G winner Besiktas on Wednesday.
Bayern Munich got a little payback against Paris Saint-Germain with a 3-1 win at the Allianz Arena on Tuesday night in Group B.
Juventus secured their place in the round of 16 of the Champions League with a 2-0 victory against Olympiakos in Greece.
Barcelona completed their Champions League Group D campaign with a 2-0 win over Sporting Lisbon at the Camp Nou.
Manchester United came from behind to beat CSKA Moscow and top their Champions League group as Jose Mourinho's men took their unbeaten home run to a club record-equalling 40th match.
Chelsea missed a chance to finish top of Champions League Group C after a 1-1 draw at home to Atletico Madrid, who will settle for a Europa League spot.
Roma progressed to the Champions League knockout stage as Group C winners after beating Qarabag 1-0 on Tuesday.
Celtic will be playing European football after Christmas despite a 1-0 Champions League defeat by Anderlecht at Parkhead.
Lionel Messi started on the bench as Barcelona secured their passage into the round of 16 of the Champions League with a 0-0 draw at Juventus.
Corentin Tolisso set up one goal and scored another to give Bayern Munich a 2-1 win over Anderlecht on Wednesday in Group B of the Champions League.
Manchester United were denied a place in the Champions League knockout phase as Michael Lang's late strike secured Basel a memorable, and deserved, victory.
Willian scored twice and was fouled for two penalties as Chelsea cruised into the Champions League knockout stages with a 4-0 win over 10-man Qarabag at the Olympic Stadium in Baku.