Michy Batshuayi scored twice as Chelsea marched on in the FA Cup with a 3-0 win over Newcastle at Stamford Bridge.
The difference in mentality of playing in the group round and the following rounds is huge. In the group stages you can, at times, afford a draw or even a defeat and survive.
Juventus climbed back back to the Serie A summit but made heavy weather of beating a Chievo side reduced to nine men.
Liverpool were dumped out of the FA Cup by West Brom in a match littered with Video Assistant Referee referrals which caused confusion on the pitch and in the stands.
Harry Kane rescued Spurs from a shock FA Cup defeat when his 82nd-minute equaliser earned them a 1-1 draw at League Two Newport County, meaning the sides replay at Wembley next month.
Arsenal target Pierre-Emerick Aubameyang was booed by some of his own fans as Borussia Dortmund's winless start to 2018 continued with a disappointing draw at home to Freiburg.
Bayern Munich recovered from a dreadful start as they came back from two goals down to beat Hoffenheim 5-2 in the Bundesliga.
Cristiano Ronaldo netted twice as Real Madrid thrashed Valencia 4-1 to bounce back from their Copa del Rey shock against Leganes, moving to within two points of Saturday's hosts in the process.
Leicester eased through to the fifth round of the FA Cup with a comfortable 5-1 victory over Peterborough at London Road.
Debutant Alexis Sanchez helped steer Manchester United into the FA Cup fifth round with two assists as Jose Mourinho's men eased past Yeovil 4-0.
Luis Suarez and Lionel Messi scored the goals as Barcelona's established stars kept new signing Philippe Coutinho out of the limelight in qualifying for the semifinals of the Copa del Rey with a 2-0 win over city rivals Espanyol.
Arsenal began life after Alexis Sanchez with a comeback victory over London rivals Chelsea to reach their first League Cup final in seven years.
Real Madrid crashed out of the Copa del Rey in the quarterfinals on away goals on Wednesday after local rivals Leganes secured a 2-1 win in the second leg at the Bernabeu.
Free-scoring Lazio produced another impressive attacking display to brush aside Udinese 3-0 on Wednesday and close the gap on Serie A leading pair Napoli and Juventus.
Sergio Escudero scored 26 seconds into the match as Sevilla defeated Atletico 3-1 at home on Tuesday to advance to the Copa del Rey semifinals 5-2 on aggregate on Tuesday.
Manchester City kept alive their hopes of an unprecedented quadruple by reaching the Carabao Cup final with a 3-2 win at Bristol City.
Swansea produced one of the shock results of the season as Virgil van Dijk's Premier League debut for Liverpool turned into a nightmare.
Douglas Costa scored the only goal as Juventus closed to within a point of Serie A leaders Napoli following a workmanlike 1-0 victory over Genoa.
Memphis Depay condemned 10-man Paris St Germain to only their second Ligue 1 defeat of the season following a superb stoppage-time strike for Lyon.
Matias Velcino's header four minutes from time earned Inter Milan a deserved 1-1 draw against Roma at Stadio Giuseppe Meazza.
Lionel Messi and Luis Suarez produced a finishing masterclass as Barcelona launched a second-half blitz at Real Betis to extend their lead at the top of the La Liga table to 11 points.
Thomas Muller reached a century of Bundesliga goals as Bayern Munich fought back to beat Werder Bremen 4-2.
Gareth Bale, Cristiano Ronaldo and Nacho Fernandez each scored twice as Real Madrid came from behind to thrash Deportivo La Coruna 7-1 at the Bernabeu.
Tottenham missed the chance to move into the Premier League's top four as Southampton delivered a battling 1-1 draw for their under-pressure boss Mauricio Pellegrino.
Napoli avenged their Coppa Italia defeat to Atalanta with a 1-0 victory in Bergamo.
Lowly Freiburg stunned RB Leipzig 2-1 in the Bundesliga on Saturday, coming from a goal down and scoring twice in four minutes to spoil their opponents' chance of cutting leaders Bayern Munich's advantage.
Sergio Aguero tormented Newcastle once again as Premier League leaders Manchester City got back to winning ways with a 3-1 win at the Etihad Stadium.
Arsenal eased to a 4-1 victory over Crystal Palace on Saturday as Alexis Sanchez was left out of the squad ahead of his expected move to Manchester United.
Anthony Martial's third goal in as many Premier League matches earned second-placed Manchester United a 1-0 victory at Burnley as they kept up the pressure on leaders Manchester City.
Antoine Griezmann found the net but Atletico Madrid failed to put pressure on leaders Barcelona as they were held 1-1 at home by Girona on Saturday.
Real Madrid will be firm favourites to reach another Champions League final after winning 2-1 away to Bayern Munich in the first leg of their semifinal.
Liverpool scored five but conceded two late goals as Roma gave themselves a glimmer of hope in a 5-2 defeat at Anfield after the home side had swept into a huge lead.
Liverpool will face Roma in the semifinals of the Champions League later this month as they continue their attempt to win it for the first time since 2005.
Cristiano Ronaldo scored an injury-time penalty to book Real Madrid's place in the Champions League semifinals after losing the second leg 3-1, but winning the tie 4-3 on aggregate.
Bayern Munich are through to the Champions League semifinals for the seventh time in nine years after a 0-0 draw in their quarterfinal second leg with Sevilla.
Barcelona suffered a shock Champions League defeat at the hands of Roma, losing 3-0 in their quarterfinal second leg at the Stadio Olimpico to go out 4-4 on aggregate thanks to an away goal for the Serie A side in the first leg.
Mohamed Salah and Roberto Firmino scored second-half goals as Liverpool won 2-1 at Manchester City to reach the Champions League semifinals 5-1 on aggregate.
A pair of own goals helped Barcelona take a major step toward the Champions League semifinals with a 4-1 win over Roma at the Camp Nou on Wednesday.
Liverpool drew significant first blood in their all-English Champions League quarterfinal as Manchester City were blown away in 45 minutes in a raucous 3-0 Anfield defeat.
Bayern Munich fought back from a goal down to beat Sevilla 2-1 in their Champions League quarterfinal first leg on Tuesday night at the Ramon Sanchez Pizjuan.
Cristiano Ronaldo scored a spectacular brace to hand Real Madrid a 3-0 victory over Juventus in their Champions League quarterfinal first leg on Tuesday.
Liverpool face Manchester City in an all-English Champions League quarterfinal after the draw in Switzerland on Friday.
Two goals from Lionel Messi -- one the fastest of his career and the other his 100th in the Champions League -- helped Barcelona beat Chelsea 3-0 at the Camp Nou and advance to the quarterfinals 4-1 on aggregate.
Bayern Munich coasted into the quarterfinals of the Champions League with a 3-1 win over Besiktas in Istanbul to complete an 8-1 aggregate win.
A second-half strike from Edin Dzeko sent Roma into the quarterfinals of the Champions League with a 1-0 home victory against 10-man Shakhtar Donetsk.
Sevilla are through to the Champions League quarterfinals after beating Manchester United 2-1 in their second leg at Old Trafford on Tuesday night.
Manchester City slipped to their first home defeat since December 2016 as Basel won the second leg of their Champions League last-16 tie 2-1.
Two goals in under three second-half minutes saw Juventus come back from 1-0 down to knock Tottenham Hotspur out of the Champions League, with a 2-1 win at Wembley putting them through to the quarterfinals 4-3 on aggregate.
Liverpool eased into the quarterfinals of the Champions League for the first time in nine years with no great alarm in a lifeless goalless draw at home to Porto.
Holders Real Madrid eased into the Champions League quarterfinals with a 2-1 win at 10-man Paris Saint-Germain.
David De Gea's exceptional display saved Manchester United's blushes as Jose Mourinho's men somehow escaped with a goalless draw from a match dominated by Sevilla.
Shakhtar Donetsk pulled off a second-half comeback to beat Roma 2-1 in their Champions League round-of-16 first leg in Ukraine on Wednesday night.
Bayern Munich look assured of a Champions League quarterfinal spot for a seventh straight season after thrashing 10-man Besiktas 5-0 in Germany.
Lionel Messi broke his goal duck against Chelsea to deny Antonio Conte's side a crucial lead over Barcelona in their Champions League showdown.
Sadio Mane scored a hat trick and Mohamed Salah continued his phenomenal run with a 30th goal of the season as Liverpool won 5-0 at Porto to virtually assure themselves a Champions League quarterfinal place.
Cristiano Ronaldo scored twice and Marcelo got another as Real Madrid came from a goal down to take a 3-1 lead over Paris Saint-Germain in the first leg of their Champions League clash at the Bernabeu.
Ilkay Gundogan scored twice as Manchester City put one foot in the Champions League quarterfinals with an emphatic 4-0 win over Basel.
Christian Eriksen completed a remarkable Tottenham comeback as they rallied from two down to draw with Juventus in the Champions League last 16.
The round of 16 draw for the Champions League has just concluded, and it's all smiles if you're a club from the North West of England as Manchester City are the new favourites.
Cristiano Ronaldo scored from a free kick to help Real Madrid beat Gremio 1-0 and claim the Club World Cup in Saturday's final in Abu Dhabi.