Mario Balotelli scored the winner but was later sent off as struggling Nice ended a four-match Ligue 1 losing streak by beating Dijon 1-0 at home.
Juventus survived a scare as they came from behind to beat Serie A's bottom club Benevento 2-1 at home.
Manchester City secured their 10th win in 11 Premier League games, extending their lead at the top of the table with a 3-1 victory over Arsenal at the Etihad Stadium.
Tottenham Hotspur got back to winning ways in domestic football as Son Heung-Min's goal proved enough to see off an unlucky Crystal Palace at Wembley.
Paco Alcacer was Barcelona's match-winner as his brace helped the LaLiga leaders make it 10 victories from 11 games with a 2-1 success over Sevilla.
Gaston Ramirez and Fabio Quagliarella fired Sampdoria to a 2-0 Serie A win at Genoa in the Derby della Lanterna.
Bayern Munich moved six points clear of Borussia Dortmund in the Bundesliga table with a 3-1 victory in Der Klassiker at Signal Iduna Park.
Second-placed Monaco reacted to PSG's triumph by thumping Guingamp 6-0 at home.
Edinson Cavani and Kylian Mbappe both scored twice as Paris St Germain thrashed Angers 5-0 in Ligue 1.
Atletico Madrid needed an stoppage-time goal to avoid another poor result in La Liga, earning a hard-fought 1-0 win at Deportivo La Coruna from Thomas Partey's free kick on Saturday.
Liverpool deepened West Ham United's problems as they strolled to a 4-1 win at the London Stadium.
Peter Crouch's second-half header earned Stoke a point at home to Leicester and ensured a familiar scoreline at the bet365 Stadium.
AC Milan were made to wait for confirmed qualification from the Europa League group stage after being held to a 0-0 draw in a mediocre game at AEK Athens.
Arsenal qualified from the Europa League group stage despite being held to a 0-0 home draw by Red Star Belgrade, with rivals BATE Borisov being thrashed 5-2 in Cologne.
Managerless Everton crashed out of the Europa League with two Group E games left to play as they were beaten 3-0 at Lyon.
Tottenham delivered one of the finest victories in the club's history as Dele Alli scored twice in a 3-1 demolition of Real Madrid.
Liverpool edged closer to qualifying for the Champions League knockout stages with a workmanlike 3-0 win over Maribor.
Borussia Dortmund and APOEL Nicosia played to a 1-1 draw on Wednesday which left both facing near-certain elimination from the Champions League.
Sevilla beat Spartak Moscow 2-1 to avenge their demoralising loss to the Russian club two weeks ago and move to second place in Group E of the Champions League on Wednesday.
A record-breaking goal from Sergio Aguero sent Manchester City into the Champions League knockout stages with a brilliant 4-2 win at Napoli.
Cenk Tosun denied Monaco a much-needed lifeline in their bid to avoid early elimination from the Champions League as he salvaged a 1-1 draw for Group G leaders Besiktas.
Barcelona failed to score in a Champions League group stage game for the first time in five years as Olympiakos held them to a goalless draw.
Gonzalo Higuain scored a late equaliser as Juventus drew with Sporting Lisbon 1-1 Tuesday to remain ahead of the Portuguese club in Group D of the Champions League.
Manchester United are on the brink of reaching the Champions League knockout phase after teenage Benfica goalkeeper Mile Svilar unwittingly put Jose Mourinho's men on course for another narrow win.
Left-back Layvin Kurzawa scored a second-half hat trick as Paris Saint-Germain crushed Anderlecht 5-0 to reach the knockout stages of the Champions League on Tuesday.
Celtic exited the Champions League after a 2-1 defeat to Bayern Munich in a pulsating encounter at Parkhead.
Atletico Madrid were held by 10-man Qarabag to a 1-1 draw in Group C of the Champions League on Tuesday, further damaging their chances of advancing to the knockout stages.
CSKA Moscow clawed back into Champions League contention on Tuesday with a come-from-behind 2-1 win at Basel on Tuesday.
Chelsea crumbled as Roma moved to the top of Champions League Group C with a 3-0 victory at Stadio Olimpico on Tuesday night.
Borja Valero's first goal for Inter Milan set the Nerazzurri on a path to reclaiming second place in the Serie A table as Hellas Verona were defeated 2-1 at the Stadio Marc'Antonio Bentegodi.
Cristiano Ronaldo scored from a free kick to help Real Madrid beat Gremio 1-0 and claim the Club World Cup in Saturday's final in Abu Dhabi.
Gareth Bale was the surprise hero as Real Madrid survived a shock against outsiders Al Jazira to win 2-1 in Wednesday's extra dramatic Club World Cup semifinal in Abu Dhabi.
Reigning champions Real Madrid will face Paris Saint-Germain in the Champions League round of 16, while Chelsea take on Barcelona.
Real Madrid star Cristiano Ronaldo won the fifth Ballon d'Or of his career on Thursday, matching Lionel Messi as the most-awarded winner of one of the sport's top individual honours.
A scintillating display of football from Liverpool's Fab Four saw Jurgen Klopp's side blaze their way into the Champions League knockout phase with a 7-0 victory over Spartak Moscow.
Manchester City slumped to their first defeat of the season with a 2-1 loss to Shakhtar Donetsk in their final Champions League Group F game.
Fernando Llorente and Georges-Kevin Nkoudou scored their first goals for Tottenham goal as Spurs strolled into the Champions League round of 16 by beating Apoel Nicosia.
Cristiano Ronaldo became the first player to score in every Champions League group stage match as Real Madrid beat Borussia Dortmund 3-2 at the Bernabeu.
Feyenoord finally secured their first points in Champions League Group F, rallying from a goal down to beat Napoli 2-1 on Wednesday, costing the Serie A side a spot in the round of 16.
Sevilla qualified for the round of 16 of the Champions League with a 1-1 draw at Maribor on Wednesday.
Ten-man Porto advanced out of Group G with a 5-2 defeat of a disappointing Monaco side, who also went down a man at the Estadio do Dragao.
RB Leipzig's Champions League debut ended in a 2-1 home loss to Group G winner Besiktas on Wednesday.
Bayern Munich got a little payback against Paris Saint-Germain with a 3-1 win at the Allianz Arena on Tuesday night in Group B.
Juventus secured their place in the round of 16 of the Champions League with a 2-0 victory against Olympiakos in Greece.
Barcelona completed their Champions League Group D campaign with a 2-0 win over Sporting Lisbon at the Camp Nou.
Manchester United came from behind to beat CSKA Moscow and top their Champions League group as Jose Mourinho's men took their unbeaten home run to a club record-equalling 40th match.
Chelsea missed a chance to finish top of Champions League Group C after a 1-1 draw at home to Atletico Madrid, who will settle for a Europa League spot.
Roma progressed to the Champions League knockout stage as Group C winners after beating Qarabag 1-0 on Tuesday.
Celtic will be playing European football after Christmas despite a 1-0 Champions League defeat by Anderlecht at Parkhead.
Lionel Messi started on the bench as Barcelona secured their passage into the round of 16 of the Champions League with a 0-0 draw at Juventus.
Corentin Tolisso set up one goal and scored another to give Bayern Munich a 2-1 win over Anderlecht on Wednesday in Group B of the Champions League.
Manchester United were denied a place in the Champions League knockout phase as Michael Lang's late strike secured Basel a memorable, and deserved, victory.
Willian scored twice and was fouled for two penalties as Chelsea cruised into the Champions League knockout stages with a 4-0 win over 10-man Qarabag at the Olympic Stadium in Baku.
Antoine Griezmann's stunning goal kept Atletico Madrid's Champions League hopes alive as they grabbed a vital victory over Roma.
Celtic suffered another night of European anguish against Paris St Germain in a 7-1 thrashing in the Parc des Princes.
Raheem Sterling struck a late winner as Manchester City secured top spot in Champions League Group F with a 1-0 win over Feyenoord.
Cristiano Ronaldo set another Champions League record as holders Real Madrid sealed their place in the knockout stages with a comprehensive victory against Apoel Nicosia.
Lorenzo Insigne's magical strike broke Shakhtar Donetsk's defences and Napoli went on to a 3-0 win, which gives them hope of Champions League progress.
Liverpool squandered a three-goal half-time lead to throw away the chance of early Champions League qualification as Sevilla netted a 93rd-minute equaliser in Spain.
Son Heung-Min proved the scourge of Borussia Dortmund again as his late winner ensured Tottenham will go through to the Champions League round of 16 as group winners.