Barcelona are in pole position to reach a fifth consecutive Copa del Rey final after Luis Suarez's winner saw off Valencia 1-0 at the Nou Camp.
Lionel Messi scored a stunning late free kick as Barcelona came from behind to beat Alaves and maintain their unbeaten start to LaLiga.
Antoine Griezmann, Fernando Torres and Thomas Partey were on target as Atletico Madrid were made to work for Sunday's 3-0 win over lowly Las Palmas.
Cristiano Ronaldo netted twice as Real Madrid thrashed Valencia 4-1 to bounce back from their Copa del Rey shock against Leganes, moving to within two points of Saturday's hosts in the process.
Luis Suarez and Lionel Messi scored the goals as Barcelona's established stars kept new signing Philippe Coutinho out of the limelight in qualifying for the semifinals of the Copa del Rey with a 2-0 win over city rivals Espanyol.
Real Madrid crashed out of the Copa del Rey in the quarterfinals on away goals on Wednesday after local rivals Leganes secured a 2-1 win in the second leg at the Bernabeu.
Sergio Escudero scored 26 seconds into the match as Sevilla defeated Atletico 3-1 at home on Tuesday to advance to the Copa del Rey semifinals 5-2 on aggregate on Tuesday.
Lionel Messi and Luis Suarez produced a finishing masterclass as Barcelona launched a second-half blitz at Real Betis to extend their lead at the top of the La Liga table to 11 points.
Gareth Bale, Cristiano Ronaldo and Nacho Fernandez each scored twice as Real Madrid came from behind to thrash Deportivo La Coruna 7-1 at the Bernabeu.
Antoine Griezmann found the net but Atletico Madrid failed to put pressure on leaders Barcelona as they were held 1-1 at home by Girona on Saturday.
Sevilla ended a run of five games without a win with a 3-0 victory at Espanyol.
Marco Asensio's late strike earned Real Madrid a 1-0 first-leg lead in their Copa del Rey quarterfinal with Leganes.
Sevilla scored two late goals to come from behind and beat Atletico Madrid 2-1 in the first leg of their Copa del Rey quarterfinal on Wednesday.
Lionel Messi missed a penalty as Barcelona's 29-match unbeaten record came to a shuddering halt at rivals Espanyol.
Barcelona fought back from two goals down at Real Sociedad to secure their first La Liga win at Anoeta in 11 years as the leaders kept their unbeaten record intact.
Atletico Madrid were indebted to goalkeeper Jan Oblak as they closed the gap on leaders Barcelona to six points with a narrow 1-0 win at Eibar.
Villarreal piled the pressure on under-fire Real Madrid coach Zinedine Zidane as they snatched a 1-0 win over the struggling La Liga champions at the Bernabeu.
Lionel Messi scored twice as holders Barcelona cruised into the quarterfinals of the Copa del Rey with a 5-0 victory over Celta Vigo at the Camp Nou on Thursday night.
Lucas Vazquez scored a brace as Real Madrid booked their place in the quarterfinals of the Copa del Rey following a 2-2 second-leg draw with Numancia at the Bernabeu.
Maxi Gomez headed a late equaliser to earn Celta Vigo a 2-2 draw against Real Madrid at Balaidos, where Gareth Bale had scored twice in as many first-half minutes.
Lionel Messi marked his 400th LaLiga appearance with an early goal as leaders Barcelona beat Levante 3-0 at the Nou Camp to restore their nine-point advantage.
Barcelona have reached an agreement with Liverpool to acquire midfielder Philippe Coutinho, the clubs confirmed on Saturday.
Diego Costa was sent off in his first La Liga appearance since returning to Atletico Madrid after picking up a second yellow card for his celebrations after scoring in a 2-0 win over Getafe.
Gareth Bale's penalty set Real Madrid on their way to an ultimately comfortable 3-0 win in the first leg of their Copa del Rey last-16 tie at Numancia.
Barcelona's record signing Ousmane Dembele made his long-awaited return from injury as the Catalan giants drew the first leg of their Copa del Rey round-of-16 tie with Celta Vigo 1-1.
Barcelona moved 14 points clear of Real Madrid in La Liga as three second-half goals wrapped up a convincing 3-0 victory at the Bernabeu.
Luis Suarez and Paulinho each scored twice as Barcelona tuned up for next week's Clasico with a handsome 4-0 win over Deportivo La Coruna.
Fernando Torres' first goal in La Liga this season gave Atletico Madrid a hard-fought 1-0 win over Alaves on Saturday and lifted the club into second place behind Barcelona.
Eduardo Berizzo's return to the Sevilla dugout delivered some defensive steel but no cutting edge up front as Levante ground out a goalless draw at the Ramon Sanchez Pizjuan.
Barcelona seized on the second-half dismissal of Dani Raba to beat Villarreal 2-0 and restore their five-point lead at the top of La Liga on Sunday night.
Barcelona lifted the Spanish Super Cup for a record-extending 13th time by coming from behind to beat Sevilla 2-1 on Sunday thanks to a stunning strike from France winger Ousmane Dembele and a penalty save in stoppage time from Marc-Andre ter Stegen.
Thibaut Courtois is set for a move from Chelsea to Real Madrid pending a medical, after the clubs announced they had agreed to a deal on Wednesday.
Barcelona have agreed a deal with Bayern Munich for Arturo Vidal, announcing the midfielder is set to sign a three-year contract.
Barcelona confirmed a deal to sign Malcom from Bordeaux on Tuesday, dramatically hijacking the Brazilian forward's move to Roma at the 11th hour.
Spain national team coach Julen Lopetegui will take over as Real Madrid manager after the World Cup, the Spanish club announced on Tuesday, just two days before the tournament begins in Russia.
Zinedine Zidane has shocked the football world by resigning as Real Madrid coach just days after winning a third consecutive Champions League with the La Liga giants.
Andres Iniesta's final Barcelona appearance ended in victory on an emotional evening at the Nou Camp.
Fernando Torres scored twice on his final appearance for 10-man Atletico Madrid in Sunday's 2-2 draw against Eibar.
Real Madrid blew a two-goal lead to draw 2-2 with Villarreal in their final La Liga match ahead of the Champions League final against Liverpool.
Barcelona's quest for an unbeaten La Liga season came to a shocking end with a 5-4 defeat away to Levante on Sunday.
Gareth Bale scored twice to lead Real Madrid to a 6-0 rout over Celta Vigo in La Liga on Saturday.
Atletico Madrid warmed up for the Europa League final by taking a big step towards securing second spot in LaLiga with a 1-0 success at Getafe.
Sevilla remain in the hunt for a Europa League spot as Joaquin Caparros secured his first win since taking temporary charge with a 3-2 win over Real Madrid at the Ramon Sanchez-Pizjuan.
Andres Iniesta provided two world-class assists and Ousmane Dembele added two late goals as La Liga champions Barcelona saw off Villarreal 5-1 on Wednesday to maintain their quest for an unbeaten domestic league season.
Gareth Bale's equaliser helped Real Madrid rally for a 2-2 draw against 10-man Barcelona in a combative affair on Sunday night at the Camp Nou.
Atletico Madrid slumped to their first La Liga home defeat of the season as they were beaten 2-0 by Espanyol at the Wanda Metropolitano Stadium.
Sevilla ended their winless streak and boosted their Europa League hopes with a 1-0 victory against Real Sociedad.
Lionel Messi put the icing on the cake as Barcelona clinched the La Liga title with a 4-2 victory over Deportivo La Coruna, who were relegated.
Atletico Madrid stayed mathematically in the La Liga title race, for a few hours at least, with a 1-0 victory over Alaves.
Real Madrid warmed up for the second leg of their Champions League semifinal against Bayern Munich with a 2-1 home win over Leganes.
Barcelona won their fourth successive Copa del Rey with a merciless 5-0 thrashing of Sevilla as departing hero Andres Iniesta joined the usual suspects on the scoresheet.
Substitute Juanmi struck twice to dent Atletico Madrid's hopes of a top-two La Liga finish as they went down 3-0 at Real Sociedad.
Cristiano Ronaldo scored an exquisite back-heel to rescue a point for Real Madrid in their 1-1 draw against Athletic Bilbao on Wednesday.
Barcelona's charge towards the La Liga title was held up after a much-changed side was held to a 2-2 draw at Celta Vigo, where Sergi Roberto was sent off with his side's first league red card in over a year.
A much-changed Real Madrid edged past basement club Malaga 2-1 to leapfrog Valencia into third place in LaLiga.
Atletico Madrid eased to a 3-0 win at home over Levante to strengthen their hold on second place in La Liga on Sunday.
Barcelona broke a 38-year-old La Liga record on Saturday as they extended their unbeaten streak in Spain's top flight to 39 games by beating Valencia 2-1 at the Camp Nou.
Real Madrid had to settle for a 1-1 draw at home to city rivals Atletico as Antoine Griezmann struck to cancel out Cristiano Ronaldo's opening goal.
Lionel Messi fired a hat trick as Barcelona took another big step towards the La Liga title with a 3-1 home win against Leganes.
Kevin Gameiro converted a match-winning penalty as Atletico Madrid beat struggling Deportivo La Coruna 1-0 to remain in contention for the La Liga title.