Sevilla boosted their chances of European qualification as they stretched their unbeaten run to 12 matches with a hard-fought 2-0 victory over Las Palmas at the Ramon Sanchez Pizjuan Stadium.
Cristiano Ronaldo scored twice as Real Madrid kept up the pressure on Primera Division title rivals Barcelona and Atletico Madrid with a 4-2 victory over Athletic Bilbao.
Villarreal's top-four hopes remain on track after Roberto Soldado's early goal earned them a 1-0 Primera Division win over Malaga.
Gary Neville ended his long wait for a first La Liga win as Valencia coach as late goals from Alvaro Negredo and Denis Cheryshev helped his side come from behind to beat Espanyol 2-1.
Gary Neville experienced yet more frustration as a late goal from teenager Wilfrid Kaptoum denied Valencia a much-needed win over Barcelona's reserves in the Copa del Rey.
Luka Modric's sensational strike helped Real Madrid scrape a late 2-1 win at struggling Granada.
Gary Neville's future as Valencia manager hung in the balance after his side were beaten 1-0 by fellow strugglers Real Betis, suffering a fourth league defeat in nine matches.
Barcelona were not at their best but still managed to claim a 2-0 win over Levante to put pressure on La Liga rivals Real Madrid.
Fernando Torres scored his 100th goal for Atletico Madrid as the Rojiblancos came from behind to beat Eibar 3-1 and record their first win in four matches.
Luis Suarez and Lionel Messi both scored hat-tricks as Barcelona demolished 10-man Valencia 7-0 in their semifinal first leg at the Camp Nou.
Cristiano Ronaldo's hat trick helped Real Madrid close the gap on Barcelona as they thumped Espanyol 6-0.
Gary Neville's winless Primera Division run as Valencia coach stretched to eight games on Sunday as his side were beaten 1-0 by relegation-threatened Sporting Gijon.
Goals from Lionel Messi and Luis Suarez fired Barcelona to a priceless 2-1 win over nine-man Atletico Madrid to strike a huge blow in the Primera Division title race.
Bruno Soriano's second-half penalty saw Villarreal beat Granada 1-0 and return to winning ways.
Holders Barcelona advanced to the Copa del Rey semifinals with a 3-1 defeat (5-2 aggregate) of Athletic Bilbao in their second leg quarterfinal tie at the Camp Nou on Wednesday.
Real Betis and Real Madrid played to a 1-1 draw in Seville, with Karim Benzema providing the equaliser for Zinedine Zidane's team.
Atletico Madrid were unable to reclaim top spot in the Primera Division back off Barcelona after being held to a goalless draw by 10-man Sevilla at the Viente Calderon.
Alvaro Negredo headed home in the third minute of stoppage time to give Valencia a 1-1 draw at Deportivo and earn a point Gary Neville's side barely deserved.
Lionel Messi scored a wonderful volley to give Barcelona a 2-1 win at Malaga and hand the Catalans three points.
Mateo Musacchio's late header rescued Villarreal a 2-2 draw at Espanyol, extending the visitors' unbeaten streak in the Primera Division to seven matches.
Gary Neville's Valencia laboured to a 1-1 draw against Primera Division strugglers Las Palmas in the first leg of their Copa del Rey quarterfinal at the Mestalla on Thursday night.
Holders Barcelona took charge of their Copa del Rey quarterfinal with a 2-1 first-leg victory at Athletic Bilbao.
Luis Suarez scored his second hat trick of the season as Barcelona obliterated 10-man Athletic Bilbao 6-0 at the Camp Nou.
Gareth Bale's seventh-minute opener paved the way for Real Madrid to hit five goals for the second consecutive week as they brushed aside Sporting Gijon 5-1 on Sunday, though the Wales star and Karim Benzema both departed due to injury.
A quick-fire double from Kevin Gameiro helped Sevilla beat Malaga 2-1 in a fierce Andalusian derby which saw both teams finish the game with 10 men.
Paco Alcacer's late equaliser saved Gary Neville's blushes by earning a haphazard Valencia a 2-2 draw with relegation-threatened Rayo Vallecano.
A goal from Filipe Luis and a double from Antoine Griezmann gave Atletico Madrid a 3-0 win at struggling Las Palmas to keep them top of the Primera Division for another week.
Munir El Haddadi scored both of Barcelona's goals as they recorded a 2-0 win at Espanyol to cruise through in the Copa del Rey.
Atletico Madrid returned to the top of the Primera Division standings with a 2-0 victory at Celta Vigo.
Gary Neville suffered his third defeat in all competitions as Valencia manager as Real Sociedad saw off Los Che 2-0 thanks to two second half strikes from Jonathas de Jesus.
Spain national team coach Julen Lopetegui will take over as Real Madrid manager after the World Cup, the Spanish club announced on Tuesday, just two days before the tournament begins in Russia.
Zinedine Zidane has shocked the football world by resigning as Real Madrid coach just days after winning a third consecutive Champions League with the La Liga giants.
Andres Iniesta's final Barcelona appearance ended in victory on an emotional evening at the Nou Camp.
Fernando Torres scored twice on his final appearance for 10-man Atletico Madrid in Sunday's 2-2 draw against Eibar.
Real Madrid blew a two-goal lead to draw 2-2 with Villarreal in their final La Liga match ahead of the Champions League final against Liverpool.
Barcelona's quest for an unbeaten La Liga season came to a shocking end with a 5-4 defeat away to Levante on Sunday.
Gareth Bale scored twice to lead Real Madrid to a 6-0 rout over Celta Vigo in La Liga on Saturday.
Atletico Madrid warmed up for the Europa League final by taking a big step towards securing second spot in LaLiga with a 1-0 success at Getafe.
Sevilla remain in the hunt for a Europa League spot as Joaquin Caparros secured his first win since taking temporary charge with a 3-2 win over Real Madrid at the Ramon Sanchez-Pizjuan.
Andres Iniesta provided two world-class assists and Ousmane Dembele added two late goals as La Liga champions Barcelona saw off Villarreal 5-1 on Wednesday to maintain their quest for an unbeaten domestic league season.
Gareth Bale's equaliser helped Real Madrid rally for a 2-2 draw against 10-man Barcelona in a combative affair on Sunday night at the Camp Nou.
Atletico Madrid slumped to their first La Liga home defeat of the season as they were beaten 2-0 by Espanyol at the Wanda Metropolitano Stadium.
Sevilla ended their winless streak and boosted their Europa League hopes with a 1-0 victory against Real Sociedad.
Lionel Messi put the icing on the cake as Barcelona clinched the La Liga title with a 4-2 victory over Deportivo La Coruna, who were relegated.
Atletico Madrid stayed mathematically in the La Liga title race, for a few hours at least, with a 1-0 victory over Alaves.
Real Madrid warmed up for the second leg of their Champions League semifinal against Bayern Munich with a 2-1 home win over Leganes.
Barcelona won their fourth successive Copa del Rey with a merciless 5-0 thrashing of Sevilla as departing hero Andres Iniesta joined the usual suspects on the scoresheet.
Substitute Juanmi struck twice to dent Atletico Madrid's hopes of a top-two La Liga finish as they went down 3-0 at Real Sociedad.
Cristiano Ronaldo scored an exquisite back-heel to rescue a point for Real Madrid in their 1-1 draw against Athletic Bilbao on Wednesday.
Barcelona's charge towards the La Liga title was held up after a much-changed side was held to a 2-2 draw at Celta Vigo, where Sergi Roberto was sent off with his side's first league red card in over a year.
A much-changed Real Madrid edged past basement club Malaga 2-1 to leapfrog Valencia into third place in LaLiga.
Atletico Madrid eased to a 3-0 win at home over Levante to strengthen their hold on second place in La Liga on Sunday.
Barcelona broke a 38-year-old La Liga record on Saturday as they extended their unbeaten streak in Spain's top flight to 39 games by beating Valencia 2-1 at the Camp Nou.
Real Madrid had to settle for a 1-1 draw at home to city rivals Atletico as Antoine Griezmann struck to cancel out Cristiano Ronaldo's opening goal.
Lionel Messi fired a hat trick as Barcelona took another big step towards the La Liga title with a 3-1 home win against Leganes.
Kevin Gameiro converted a match-winning penalty as Atletico Madrid beat struggling Deportivo La Coruna 1-0 to remain in contention for the La Liga title.
Lionel Messi came off the bench to net a stunning last-minute equaliser as La Liga leaders Barcelona fought back from two-goals down to draw 2-2 at Sevilla.
Gareth Bale scored twice as Real Madrid warmed up for their Champions League clash against Juventus with a 3-0 win at struggling Las Palmas, where Cristiano Ronaldo was rested.
Substitute Enes Unal scored twice in the final nine minutes as Villarreal dealt a major blow to Atletico Madrid's hopes of catching Barcelona at the top of La Liga with a 2-1 victory.
Cristiano Ronaldo scored his 50th career hat trick, then went on to add a fourth goal as Real Madrid beat Girona 6-3 in La Liga on Sunday.