Villarreal tightened their grip on a place in the Champions League and moved just two points behind Real Madrid with a comprehensive 3-0 win over 10-man Levante.
Zinedine Zidane suffered his first defeat as Real Madrid coach as Antoine Griezmann gave local rivals Atletico Madrid a 1-0 victory at the Bernabeu.
Cristiano Ronaldo missed a penalty as Real Madrid slipped even further behind leaders Barcelona in the Primera Division title race by drawing 1-1 at Malaga.
Atletico Madrid's hopes of catching Primera Division leaders Barcelona suffered a setback on Sunday evening as they were held to a 0-0 draw by Villarreal at the Vicente Calderon.
Barcelona survived a late onslaught to beat Las Palmas and remain in the driving seat at the top of the Primera Division.
Lionel Messi passed 300 Primera Division goals as Barcelona extended their lead at the top to six points with a 3-1 victory over Sporting Gijon.
Luis Suarez finished off a collector's item from the penalty spot to score a hat trick as Barcelona hammered Celta Vigo 6-1 with a majestic second-half display.
Fernando Torres scored in consecutive matches for the first time in almost two and a half years as Atletico Madrid edged past Getafe to leapfrog rivals Real Madrid into second place in the Primera Division.
Sevilla boosted their chances of European qualification as they stretched their unbeaten run to 12 matches with a hard-fought 2-0 victory over Las Palmas at the Ramon Sanchez Pizjuan Stadium.
Cristiano Ronaldo scored twice as Real Madrid kept up the pressure on Primera Division title rivals Barcelona and Atletico Madrid with a 4-2 victory over Athletic Bilbao.
Villarreal's top-four hopes remain on track after Roberto Soldado's early goal earned them a 1-0 Primera Division win over Malaga.
Gary Neville ended his long wait for a first La Liga win as Valencia coach as late goals from Alvaro Negredo and Denis Cheryshev helped his side come from behind to beat Espanyol 2-1.
Gary Neville experienced yet more frustration as a late goal from teenager Wilfrid Kaptoum denied Valencia a much-needed win over Barcelona's reserves in the Copa del Rey.
Luka Modric's sensational strike helped Real Madrid scrape a late 2-1 win at struggling Granada.
Gary Neville's future as Valencia manager hung in the balance after his side were beaten 1-0 by fellow strugglers Real Betis, suffering a fourth league defeat in nine matches.
Barcelona were not at their best but still managed to claim a 2-0 win over Levante to put pressure on La Liga rivals Real Madrid.
Fernando Torres scored his 100th goal for Atletico Madrid as the Rojiblancos came from behind to beat Eibar 3-1 and record their first win in four matches.
Luis Suarez and Lionel Messi both scored hat-tricks as Barcelona demolished 10-man Valencia 7-0 in their semifinal first leg at the Camp Nou.
Cristiano Ronaldo's hat trick helped Real Madrid close the gap on Barcelona as they thumped Espanyol 6-0.
Gary Neville's winless Primera Division run as Valencia coach stretched to eight games on Sunday as his side were beaten 1-0 by relegation-threatened Sporting Gijon.
Goals from Lionel Messi and Luis Suarez fired Barcelona to a priceless 2-1 win over nine-man Atletico Madrid to strike a huge blow in the Primera Division title race.
Bruno Soriano's second-half penalty saw Villarreal beat Granada 1-0 and return to winning ways.
Holders Barcelona advanced to the Copa del Rey semifinals with a 3-1 defeat (5-2 aggregate) of Athletic Bilbao in their second leg quarterfinal tie at the Camp Nou on Wednesday.
Real Betis and Real Madrid played to a 1-1 draw in Seville, with Karim Benzema providing the equaliser for Zinedine Zidane's team.
Atletico Madrid were unable to reclaim top spot in the Primera Division back off Barcelona after being held to a goalless draw by 10-man Sevilla at the Viente Calderon.
Alvaro Negredo headed home in the third minute of stoppage time to give Valencia a 1-1 draw at Deportivo and earn a point Gary Neville's side barely deserved.
Lionel Messi scored a wonderful volley to give Barcelona a 2-1 win at Malaga and hand the Catalans three points.
Mateo Musacchio's late header rescued Villarreal a 2-2 draw at Espanyol, extending the visitors' unbeaten streak in the Primera Division to seven matches.
Gary Neville's Valencia laboured to a 1-1 draw against Primera Division strugglers Las Palmas in the first leg of their Copa del Rey quarterfinal at the Mestalla on Thursday night.
Holders Barcelona took charge of their Copa del Rey quarterfinal with a 2-1 first-leg victory at Athletic Bilbao.
Luis Suarez and Paulinho each scored twice as Barcelona tuned up for next week's Clasico with a handsome 4-0 win over Deportivo La Coruna.
Fernando Torres' first goal in La Liga this season gave Atletico Madrid a hard-fought 1-0 win over Alaves on Saturday and lifted the club into second place behind Barcelona.
Eduardo Berizzo's return to the Sevilla dugout delivered some defensive steel but no cutting edge up front as Levante ground out a goalless draw at the Ramon Sanchez Pizjuan.
Barcelona seized on the second-half dismissal of Dani Raba to beat Villarreal 2-0 and restore their five-point lead at the top of La Liga on Sunday night.
Saul Niguez scored the only goal as Atletico Madrid beat Real Betis 1-0 to keep Diego Simeone's team in the chase for the La Liga title.
Cristiano Ronaldo celebrated his fifth Ballon d'Or award with a brace as Real Madrid swept past Sevilla 5-0 following a blistering first-half display at the Bernabeu.
Markel Bergara fired 10-man Getafe to a shock victory over second-placed Valencia to leave Barcelona five points clear at the top of the La Liga table.
Sergio Ramos was sent off for a record 19th time in La Liga as Real Madrid drew 0-0 Athletic Bilbao and failed to take advantage of Barcelona's earlier slip.
Atletico Madrid cut the gap on La Liga leaders Barcelona to six points with a 2-1 comeback win against Real Sociedad.
Barcelona failed to stretch their lead at the top of the Liga table to seven points as Celta Vigo held them to a 2-2 draw in a fine match at the Bernabeu.
Fernando Torres scored his first two goals of the season to help Atletico Madrid reach the Copa del Rey last 16 with a 3-0 win over Elche on Wednesday.
Barcelona swept into the last 16 of the Copa del Rey with a 5-0 win over Real Murcia at the Camp Nou.
Gareth Bale made a welcome return from injury to spare Real Madrid embarrassment in their Copa del Rey clash with Segunda B leaders Fuenlabrada.
Lionel Messi had a legitimate goal controversially denied as La Liga leaders Barcelona hit back to snatch a 1-1 draw at second-placed Valencia.
Atletico Madrid romped to a 5-0 win at Levante, which put them back above their city rivals Real into third place.
Cristiano Ronaldo struck on the rebound after his penalty was saved to give Real Madrid a 3-2 victory over Malaga in their LaLiga clash at the Bernabeu.
Lionel Messi has ended speculation about his future by signing a new contract with Barcelona until 2021.
Valencia kept pace with Spanish leaders Barcelona on Sunday by beating Espanyol 2-0 for an eighth straight league win despite having coach Marcelino Garcia Toral sent off.
Atletico Madrid and Real Madrid shared a rare goalless draw in the first derby at the Wanda Metropolitano in a result that will have delighted league leaders Barcelona.
Luis Suarez scored a brace as Barcelona recorded a 3-0 victory against Leganes to extend their lead at the summit of LaLiga.
Marco Asensio struck an instant classic as Real Madrid returned to winning ways with a 3-0 victory over Las Palmas.
Paco Alcacer was Barcelona's match-winner as his brace helped the LaLiga leaders make it 10 victories from 11 games with a 2-1 success over Sevilla.
Atletico Madrid needed an stoppage-time goal to avoid another poor result in La Liga, earning a hard-fought 1-0 win at Deportivo La Coruna from Thomas Partey's free kick on Saturday.
Girona claimed a stunning 2-1 victory over Real Madrid to deal a major blow to the La Liga champions' hopes of retaining their title.
Lionel Messi and Paulinho hit the target as Barcelona crept past Athletic Bilbao to maintain their four-point lead in La Liga.
Atletico Madrid are still undefeated and in fourth place in La Liga after notching their fifth draw, a disappointing 1-1 result at home versus Villarreal.
Valencia extended their winning streak to seven matches to stay on Barcelona's heels at the top of La Liga with a 2-1 victory at Alaves.
Real Madrid needed two second-half penalties to secure a 2-0 win over third-tier side Fuenlabrada in their first outing in this season's Copa del Rey
Gerard Deulofeu had a goal and an assist and Jose Arnaiz scored on his senior debut as Barcelona secured a comfortable 3-0 win in the first leg of their Copa del Rey tie against Real Murcia at Estadio Nueva Condomina.
Marco Asensio had a hand in two goals as Real Madrid recorded their fourth successive La Liga win with a routine 3-0 success over Eibar.