Liverpool's slim Champions League hopes suffered a huge blow as they were held to a disappointing 0-0 draw at West Brom.
Mauricio Pochettino frustrated the fans that once adored him as Tottenham twice came from behind to secure a draw on his first return to Southampton.
There will be no fairytale end to Steven Gerrard's Liverpool career after Aston Villa came from behind to deservedly book their place in the FA Cup final with a 2-1 win over the Reds.
Harry Kane struck yet again as Tottenham beat Newcastle 3-1 to condemn the Magpies to a sixth successive Premier League defeat and rekindle their own hopes of European qualification.
A bizarre own goal from West Ham's James Collins helped Manchester City back to winning ways in the Premier League.
A fumble from Reading goalkeeper Adam Federici in extra time handed holders Arsenal a 2-1 victory and a place in the FA Cup final.
Chelsea have one hand on the Premier League title after Eden Hazard fired them to a 1-0 win at Stamford Bridge.
Raheem Sterling grabbed the headlines on and off the field as Liverpool reignited their Champions League hopes with a 2-0 defeat of 10-man Newcastle.
Louis van Gaal's dream turned into reality as Manchester United put four goals past City in a superb derby win at Old Trafford.
Cesc Fabregas scored an 88th-minute winner as Chelsea restored their seven-point lead at the top of the table with a 1-0 victory at West London rivals QPR.
Aaron Ramsey marked his 150th Premier League appearance with a first half winner as Arsenal closed the gap on leaders Chelsea to four points with a hard-fought 1-0 win at Turf Moor.
Christian Benteke scored his eighth goal in six games to hand Tim Sherwood a winning return to Tottenham and ease Aston Villa's relegation fears.
Playmaker Philippe Coutinho was Liverpool's FA Cup saviour again as his solitary goal beat Blackburn 1-0 to book a Wembley semifinal with Aston Villa.
Manchester City's grip on the Premier League title was loosened further after a controversial Glenn Murray goal put Crystal Palace on the way to a 2-1 victory.
Harry Kane's first outing as captain of Tottenham failed to inspire Spurs in an insipid 0-0 draw at Burnley.
Chelsea responded from conceding a Charlie Adam goal from his own half and losing Diego Costa to a hamstring injury to beat Stoke 2-1 and move seven points clear in the Premier League title race.
Manchester United climbed above their 'noisy neighbours' into third position thanks to a 3-1 win over Aston Villa which included a stunning strike from Wayne Rooney.
Arsenal kept up the pressure at the top of the Premier League as Liverpool were blown away 4-1 at the Emirates Stadium, where Reds contract rebel Raheem Sterling failed to make an impact.
A moment of madness from Liverpool captain Steven Gerrard saw him sent off just 43 seconds after coming on in his final appearance against Manchester United, whose 2-1 victory at Anfield.
Chelsea survived a major scare to secure a 3-2 win at Hull City and restore their six-point lead at the top of the Premier League.
Referee Neil Swarbrick took the gloss off Manchester City's return to winning ways as the Premier League suffered yet another mistaken identity controversy.
Harry Kane's dream week got even better on Saturday as the Tottenham striker followed his first England callup with a maiden Premier League hat trick as embattled Leicester were defeated in a thrilling 4-3 encounter.
Olivier Giroud's first-half double handed Arsenal a sixth successive Premier League victory as they survived a spirited fightback to win 2-1 at Newcastle.
Liverpool maintained the pressure in the race for Champions League qualification as Jordan Henderson's fortunate second-half goal saw off Swansea at the Liberty Stadium to seal a 1-0 win.
Wayne Rooney and Manchester United delivered a knockout performance as Tottenham were blown away at Old Trafford.
Chelsea missed the opportunity to go eight points clear at the top of the Premier League by drawing 1-1 against Southampton.
George Boyd struck a stunning second-half winner as Burnley enhanced their survival hopes by further ravaging Manchester City's fading title quest with a 1-0 victory at Turf Moor.
Olivier Giroud's thunderbolt helped Arsenal see off the challenge of West Ham and cement their place in the top four of the Premier League with a 3-0 victory.
Danny Welbeck came back to haunt Louis van Gaal as the Manchester United manager was subjected to a night of despair and defeat at Old Trafford.
There was little magic in this FA Cup quarterfinal on an afternoon when, for once, Liverpool's free-flowing football deserted them in the face of a committed and well-organised Blackburn side.
Michael Carrick bade farewell to Old Trafford by helping set up the goal that delivered a 1-0 win for Manchester United over Watford.
Champions Manchester City became the first club to amass 100 Premier League points after Gabriel Jesus scored a dramatic stoppage-time winner at Southampton.
Tottenham said goodbye to Wembley in style as they came from behind to beat Leicester 5-4 in a thrilling final-day Premier League encounter.
Ayoze Perez struck twice to end Chelsea's faint hopes of Champions League qualification as Newcastle secured a top-10 finish on their return to the Premier League.
Liverpool secured a top-four spot with very little fuss as Mohamed Salah's new Premier League goalscoring record paved the way for a 4-0 victory over Brighton.
Arsene Wenger bowed out with a victory as Pierre-Emerick Aubameyang's first-half goal secured a 1-0 win for Arsenal in their season finale against Huddersfield.
West Ham and Manchester United played out a dull goalless draw at the London Stadium -- although the result was enough to see Jose Mourinho's side secure second place in the Premier League.
Yaya Toure bade farewell to the Etihad Stadium as champions Manchester City set a hat trick of Premier League records in a routine 3-1 win over Brighton.
Jamie Vardy returned to haunt Arsene Wenger on his farewell tour as Leicester cruised past 10-man Arsenal 3-1.
Tottenham overcame a nervy night at Wembley to book their Champions League place for next season with a 1-0 win over Newcastle.
Huddersfield secured their Premier League status with a valiant 1-1 draw at Stamford Bridge which significantly dented Chelsea's slim top-four hopes.
Southampton took a huge step towards safety as a 1-0 win at Swansea inched their Welsh rivals towards the Premier League trapdoor and relegated West Brom in the process.
Arsenal gave Arsene Wenger a memorable Emirates Stadium send-off as the outgoing boss saw his side thrash Burnley.
Chelsea's Champions League hopes for next season received a boost following Sunday's narrow victory over Liverpool.
Manchester City failed to fire on the day they were presented with the Premier League trophy as Huddersfield Town claimed a vital point at the Etihad Stadium.
Tom Davies scored deep into added time as Everton salvaged a 1-1 draw against 10-man Southampton at Goodison Park, preventing their opponents from escaping the Premier League relegation zone.
West Bromwich Albion kept their slim survival hopes alive after Jake Livemore's dramatic injury time goal earned a 1-0 win against Tottenham Hotspur.
Pascal Gross scored the goal which sank Manchester United 1-0 to guarantee Premier League football for Brighton next season.
Harry Kane did his talking on the pitch as Tottenham reasserted themselves in the race for the Champions League with a 2-0 win over Watford.
Arsene Wenger was denied a point on his last visit to Old Trafford as Arsenal manager when Marouane Fellaini's injury-time header snatched victory for Manchester United.
Manchester City surpassed 100 Premier League goals for the season and left West Ham waiting to confirm top flight football next season with a 4-1 win at the London Stadium.
Chelsea's chase for a top-four Premier League spot gathered pace as Cesc Fabregas scored a landmark goal to deepen Swansea's relegation concerns.
Premier League leading scorer Mohamed Salah had a rare off day as Liverpool continue to stumble towards guaranteeing a top-four finish after a goalless draw at home to Stoke.
Manchester City celebrated their title success in style with a resounding 5-0 win over Swansea at the Etihad Stadium.
Olivier Giroud proved the scourge of Southampton once again, setting Chelsea on course for FA Cup semifinal success and a mouth-watering clash with Manchester United.
A late flurry of goals saw Arsenal secure a 4-1 win over West Ham in their first game since Arsene Wenger revealed he is stepping down as boss.
Ander Herrera has Manchester United dreaming of FA Cup glory after Tottenham Hotspur again suffered semifinal sorrow.
A late strike from Salomon Rondon helped bottom-of-the-table West Bromwich Albion come from behind to draw 2-2 against Liverpool on Saturday at The Hawthorns.
Victor Moses was the match-winner as Chelsea eased the pressure on London rivals Arsenal by denting Burnley's surge for sixth place.
Southampton halted their losing run but a goalless draw at Leicester does little for their Premier League survival hopes.