Olivier Giroud struck twice as FA Cup holders Arsenal beat Middlesbrough 2-0 at the Emirates Stadium to book their place in the quarterfinals.
Liverpool exorcised some demons at Selhurst Park by reaching the FA Cup quarterfinals with an impressive win against Crystal Palace.
Willian struck an 89th-minute winner as Chelsea beat Everton 1-0 but the Premier League leaders could face disciplinary action once more after Branislav Ivanovic appeared to headbutt James McCarthy.
Sergio Aguero and Manchester City rediscovered their touch as the champions turned on the style in the second half to win 4-1 at Stoke.
Manchester United cut out the long-ball tactics but they still had to battle their way to a 3-1 win over Burnley at Old Trafford.
Liverpool's Mario Balotelli picked the perfect time to score his first Premier League goal for the club as he stole the headlines from the battle between England strikers present and, potentially, future.
Arsenal moved back into the Premier League top four as they edged out bottom club Leicester 2-1 at the Emirates Stadium.
West Ham were denied a first Premier League win over Manchester United in seven years and 13 attempts by Daley Blind's stoppage-time strike.
Even the occasion of his final Premier League Merseyside derby could not inspire Liverpool captain Steven Gerrard to more heroics as the 224th meeting of the clubs disappointingly finished goalless.
Branislav Ivanovic's rocket gave Chelsea a crucial 2-1 win at Aston Villa - despite the hosts ending their 11-hour goal drought.
Substitute James Milner struck a superb injury-time free-kick as lacklustre champions Manchester City rescued a point with a 1-1 draw against Hull.
Harry Kane inspired boyhood club Tottenham to victory over Arsenal in a wonderfully frantic and frenetic north London derby.
Philippe Coutinho celebrated his new five-year contract with an added-time winner as Liverpool kept their FA Cup hopes alive in a dramatic late turnaround at Bolton.
Manchester United overcame Cambridge United in their FA Cup replay on Tuesday, winning 3-0 less than two weeks after a humbling 0-0 draw.
Juan Cuadrado has completed his move from Fiorentina to Chelsea for a total fee of 35 million euros, including bonuses, although Italy's prime minister Matteo Renzi does not approve of the transfer.
Arsenal closed the gap on the top four of the Premier League as they romped to a 5-0 win over Aston Villa, whose goal drought continued at the Emirates Stadium.
Under-siege Chelsea retained a five-point lead at the top of the Premier League after repelling Manchester City at Stamford Bridge.
Striker Daniel Sturridge enjoyed the perfect return from injury as he scored within 12 minutes of coming off the bench to give Liverpool's Champions League ambitions a timely boost.
Robin van Persie ended his dry spell with a spectacular finish that propelled Manchester United to a comfortable 3-1 win over Leicester.
Tottenham's Harry Kane further enhanced his growing reputation with two goals in a convincing 3-0 win over West Brom in the Premier League.
Christian Eriksen struck after 88 minutes as Tottenham killed off a stunning Che Adams-inspired Sheffield United comeback to reach the Capital One Cup final with a 3-2 aggregate win.
Branislav Ivanovic kept his head as Chelsea edged a frenetic, ill-tempered clash with Liverpool to advance to the Capital One Cup final.
Arsenal held firm to see off Championship side Brighton & Hove Albion and book their place in the fifth round of the FA Cup.
Liverpool avoided an FA Cup upset at home to Bolton but even on a day of shocks it was not much of an achievement after a toothless display against Championship opponents Bolton.
Leicester came from behind to net a stoppage-time winner from Jeff Schlupp which beat Tottenham 2-1 in the fourth round of the FA Cup at White Hart Lane.
Bradford brilliantly responded from two goals down to win 4-2 at Chelsea and dump the Premier League leaders out of the FA Cup at Stamford Bridge.
Chelsea loanee Patrick Bamford and Kike struck in the second half as Championship side Middlesbrough produced a shock 2-0 win over Premier League champions Manchester City in the FA Cup.
League Two Cambridge earned a FA Cup fourth-round replay at Old Trafford after Louis van Gaal and his Manchester United side endured an uncomfortable Friday evening at the Abbey Stadium.
Chelsea manager Jose Mourinho still has not won a semifinal against Liverpool after Raheem Sterling's flash of brilliance earned the Reds a deserved 1-1 draw.
Santi Cazorla and Olivier Giroud struck in each half as Arsenal stunned lacklustre champions Manchester City 2-0 at the Etihad Stadium.
Swansea produced one of the shock results of the season as Virgil van Dijk's Premier League debut for Liverpool turned into a nightmare.
Tottenham missed the chance to move into the Premier League's top four as Southampton delivered a battling 1-1 draw for their under-pressure boss Mauricio Pellegrino.
Sergio Aguero tormented Newcastle once again as Premier League leaders Manchester City got back to winning ways with a 3-1 win at the Etihad Stadium.
Arsenal eased to a 4-1 victory over Crystal Palace on Saturday as Alexis Sanchez was left out of the squad ahead of his expected move to Manchester United.
Anthony Martial's third goal in as many Premier League matches earned second-placed Manchester United a 1-0 victory at Burnley as they kept up the pressure on leaders Manchester City.
Eden Hazard moved past the 100 career league goals milestone with two goals as he orchestrated Chelsea's 4-0 win over Brighton & Hove Albion at the AMEX stadium.
Chaotic Chelsea ended a five-hour scoring drought before advancing in the FA Cup with a 5-3 penalty shootout win over Norwich.
Theo Walcott has completed his £20 million move to Everton, ending a 12-year stint at Arsenal in the hopes of a fresh start under Sam Allardyce.
Leicester became the first team in English football to score a goal via a VAR decision as they overcame Fleetwood 2-0 in their FA Cup replay.
Manchester United maintained their 100 percent start to 2018 with a comfortable 3-0 victory over a Stoke side watched by their incoming boss Paul Lambert.
Liverpool ended Manchester City's unbeaten Premier League record with a 4-3 win in a sensational game at Anfield in which City almost recovering from 4-1 down.
Bournemouth scored twice in four minutes as they came from a goal down to see off Arsenal 2-1 at the Vitality Stadium for their first-ever win over the Gunners.
Harry Kane struck twice to become Tottenham Hotspur's all-time leading Premier League scorer as they beat Everton 4-0 at Wembley.
Chelsea endured a third successive goalless draw in an enthralling encounter against excellent 10-man Leicester.
Arsenal stood firm in a Carabao Cup semifinal first-leg stalemate with Chelsea at Stamford Bridge.
Manchester City needed a late Sergio Aguero winner to claim a 2-1 advantage from the first leg of their Carabao Cup semifinal against Bristol City.
Arsene Wenger lost an FA Cup third-round tie for the first time as holders Arsenal crashed out against Nottingham Forest in an action-packed clash at the City Ground.
Jan Vertonghen scored his first club goal in five years and Harry Kane bagged a brace but Tottenham's FA Cup win over AFC Wimbledon was far from straightforward.
Sergio Aguero struck twice in two minutes as Manchester City came from behind to overpower Burnley 4-1 in the FA Cup third round.
Chelsea's peripheral players failed to impress in a goalless draw at Carrow Road as Norwich earned an FA Cup third-round replay.
League One Fleetwood gave Leicester a real scare but the Premier League side escaped Highbury Stadium with a goalless draw in their FA Cup third round tie.
Jesse Lingard's latest scintillating strike and substitute Romelu Lukaku's late effort secured Manchester United a 2-0 victory over Derby in the third round of the FA Cup.
Virgil van Dijk enjoyed a dream debut for Liverpool by heading the winner in front of the Kop in the 230th Merseyside derby as they knocked Everton out of the FA Cup.
Son Heung-min and Pedro Obiang each scored a stunner as Tottenham were held by West Ham to a 1-1 draw at Wembley.
Hector Bellerin hit a stoppage-time equaliser as Arsenal held Chelsea to a 2-2 draw after an enthralling encounter at Emirates Stadium.
Kevin De Bruyne made a dramatic return to action as Manchester City eased back to winning ways with a convincing 3-1 victory over Watford.
Fernando Llorente returned to haunt former club Swansea and Dele Alli struck late on as Tottenham claimed a fifth win in six Premier League games on a rainy night in south Wales.
Andy Carroll's dramatic double lifted West Ham out of the relegation zone, as the Hammers were trailing fellow strugglers West Brom until two goals from their towering striker -- the second deep in stoppage time -- secured a 2-1 win.
Centre-back Ragnar Klavan was Liverpool's unlikely match-winner at Burnley as his close-range header in the fourth minute of added time made light of the absence of three of the 'Fab Four'.
Manchester United brought an end to a run of three successive draws as goals from Anthony Martial and Jesse Lingard secured a 2-0 victory over Everton at Goodison Park.