Jose Mourinho's position as Chelsea boss appears ever more precarious after Jurgen Klopp's Liverpool inflicted Chelsea's sixth defeat in 11 Premier League games.
Wayne Rooney, Michael Carrick and Ashley Young all missed penalties as Middlesbrough knocked Manchester United out of the Capital One Cup on penalties at Old Trafford.
Wilfried Bony and Kelechi Iheanacho were among the goalscorers as Manchester City eased into the Capital One Cup quarterfinals with a 5-1 win over Crystal Palace.
Jurgen Klopp's first victory as Liverpool manager was secured via the unlikeliest of sources as defender Nathaniel Clyne scored the only goal to beat Bournemouth 1-0.
The pressure on Jose Mourinho cranked up another notch as holders Chelsea crashed out of the Capital One Cup with a 5-4 loss on penalties at 10-man Stoke following a 1-1 draw after 120 minutes.
Arsenal were unceremoniously dumped out of the Capital One Cup on a damaging night as Sheffield Wednesday blew them away with a stunning 3-0 victory at Hillsborough.
Southampton's Sadio Mane scored late to deny Jurgen Klopp his first win as Liverpool manager, with Sunday's Premier League match finishing 1-1.
Harry Kane returned to form as he struck a hat trick to sink sorry Bournemouth in the Premier League on Sunday.
Manchester City moved to the top of the Premier League despite a dull goalless draw in the Manchester derby at Old Trafford.
Arsenal moved to the top of the Premier League following a hard-earned 2-1 win over Everton at the Emirates Stadium.
Chelsea slumped to their fifth defeat of the Premier League season amid controversial scenes as West Ham won 2-1 at Upton Park.
Georginio Wijnaldum hit Norwich for four as Newcastle finally ended their wait for a Premier League victory at the ninth attempt with a 6-2 win on Sunday.
Arsenal moved to second in the Premier League with an impressive 3-0 win at Watford.
Wayne Rooney scored his first goal at Goodison Park for eight years as Manchester United coasted to a 3-0 victory on an emotional afternoon for Everton.
Raheem Sterling hit a first-half hat-trick and Wilfried Bony struck twice as Barclays Premier League leaders Manchester City overcame promoted Bournemouth 5-1 at the Etihad Stadium.
Diego Costa eased Chelsea manager Jose Mourinho's concerns as Aston Villa's hapless defenders heaped more misery on Tim Sherwood at Stamford Bridge.
Jurgen Klopp, the self-proclaimed "Normal One," left White Hart Lane with what he labelled a "normal result" as his new Liverpool side drew 0-0 with Tottenham.
Cristiano Ronaldo became Real Madrid's all-time top scorer as Rafael Benitez's side saw off Levante 3-0 to go top of the Primera Division.
Liverpool have confirmed the appointment of Jurgen Klopp as their new manager to replace Brendan Rodgers.
Liverpool sacked manager Brendan Rodgers on Sunday, with the decision coming just hours after a 1-1 Merseyside derby draw at Everton.
Alexis Sanchez's stunning first-half brace helped Arsenal blow away Manchester United 3-0 at the Emirates Stadium to move second in the Premier League.
Christian Eriksen stunned Swansea with two brilliant free kicks after Tottenham striker Harry Kane had scored a spectacular own goal.
Liverpool manager Brendan Rodgers maintained his unbeaten record in Merseyside derbies but could not keep his job as he was sacked after his side managed a 1-1 draw at Everton.
Chelsea capitulated and were booed off as Southampton won at Stamford Bridge for the first time in almost 14 years to leave Jose Mourinho contemplating a fourth loss from eight Premier League games this season.
Sergio Aguero scored five goals in a sensational 20-minute spell as Manchester City came from behind to crush Newcastle 6-1 in the Premier League.
Substitutes Ramires and Willian got Chelsea out of jail as they fought back from 2-0 down at Newcastle to snatch a point.
Wayne Rooney ended his 11-match goal drought as Manchester United climbed to the top of the Premier League for the first time in over two years with victory over Sunderland.
Arsenal came from behind to beat Leicester 5-2 on the road thanks to a hat trick from Alexis Sanchez.
Liverpool overcame Aston Villa with a 3-2 win in a thriller at Anfield.
Harry Kane netted his first Tottenham goal in over 640 minutes of football as he helped Tottenham come from behind to beat Premier League leaders Manchester City 4-1 at White Hart Lane.
West Ham United beat Everton 3-1 at Goodison Park on Sunday to secure their first Premier League points of the season as Marco Silva tasted defeat for the first time as Everton manager.
Manchester United ruined Watford's first perfect start to a Premier League season with a 2-1 victory at Vicarage Road on Saturday.
Manchester City comfortably defeated Fulham 3-0 at the Etihad Stadium on Saturday to stay within two points of leaders Liverpool and Chelsea.
A free kick by midfielder Granit Xhaka and a goal by Mesut Ozil gave Arsenal a 2-1 win at Newcastle United despite a stuttering first-half performance on Saturday.
A hat trick from Eden Hazard gave Chelsea their fifth win in five games, a 4-1 victory over Cardiff City that sent them to the top of the Premier League on Saturday.
Liverpool continued their perfect start to the season after a goal in each half gave them a 2-1 victory over Tottenham Hotspur at Wembley Stadium on Saturday.
Watford came from behind with two set-piece goals to beat Tottenham Hotspur 2-1 at Vicarage Road on Sunday, ending the visitors' perfect start to the Premier League season while maintaining their own.
Manchester United fans showed their backing for manager Jose Mourinho after Romelu Lukaku struck twice as United returned to winning ways after two successive Premier League losses with a 2-0 victory at Burnley on Sunday.
Alexandre Lacazette scored his first goal of the season in his first start under Unai Emery, handing Arsenal a 3-2 victory away against Cardiff City.
Raheem Sterling and Kyle Walker each scored as Manchester City defeated Newcastle United 2-1 at the Etihad Stadium on Saturday.
Chelsea stretched their perfect Premier League start to four games after second-half goals from substitute Pedro and Eden Hazard gave them a 2-0 home win over Bournemouth on Saturday.
Sadio Mane and Roberto Firmino scored in the first half as Liverpool won their first four Premier League games for the first time with a 2-1 victory over Leicester City on Saturday at the King Power Stadium.
Liverpool will host Chelsea while Frank Lampard's Derby County will visit Manchester United following the third-round draw for the Carabao Cup held on Thursday.
Tottenham piled on more woe for Manchester United, running out 3-0 winners at Old Trafford on Monday night to hand the hosts a second Premier League defeat in as many weeks.
Chelsea left it late but came away with a 2-1 win over Newcastle thanks to a late DeAndre Yedlin own goal St James' Park on Sunday.
Unfancied Watford continued their great start to the Premier League season with a third successive win when they beat visiting Crystal Palace 2-1 on Sunday.
Mohamed Salah's 23rd-minute strike was enough to earn Liverpool a 1-0 win over a dogged Brighton and Hove Albion and give them an early top spot in the Premier League with three wins out of three.
Arsenal celebrated their first Premier League win of the season under new manager Unai Emery after coming from behind to beat London rivals West Ham United 3-1 in an action-packed match on Saturday.
Manchester City stumbled to a 1-1 draw at Wolves in a tense lunchtime encounter at Molineux.
Liverpool's James Milner's converted a penalty on the stroke of halftime and Sadio Mane added a late second goal to secure a hard-fought 2-0 win at Crystal Palace in the Premier League on Monday.
Manchester United conceded three first-half goals as they slumped to a 3-2 defeat at Brighton in a game illuminated by a superb goal from Seagulls striker Glenn Murray.
Sergio Aguero scored his 13th hat trick for Manchester City as the Premier League champions brushed Huddersfield aside in a 6-1 win at the Etihad Stadium.
Chelsea secured their second straight win of the season and sentenced Arsenal to a second defeat with a 3-2 win in a Stamford Bridge thriller that had seen Arsenal fight back from two goals down to level.
Leicester City had Jamie Vardy sent off but it did not stop them from recording a comfortable 2-0 home victory over Wolverhampton Wanderers in the Premier League on Saturday.
Harry Kane finally ended his August goalscoring drought as England's World Cup luminaries inspired Tottenham Hotspur to a morale-boosting 3-1 Premier League win over newcomers Fulham on Saturday.
Kenedy missed a 96th-minute penalty as Cardiff secured a 0-0 draw against 10-man Newcastle in their first home game back in the Premier League.
Manchester City midfielder Kevin De Bruyne is facing a spell on the sidelines after injuring his right knee in training on Wednesday.
Manchester City, who romped to Premier League success by 19 points last season, began the defence of their title with a 2-0 win away against Arsenal and new manager Unai Emery on Sunday.
Sadio Mane had two goals for the first time since February 2017 and Mohamed Salah also scored as Liverpool opened their Premier League season with a 4-0 victory over West Ham United at Anfield.
Richarlison scored twice in his first Premier League appearance for 10-man Everton, but a late goal from Raul Jimenez helped Wolverhampton Wanderers salvage a 2-2 draw at the Molineux Stadium.