A classy volley from Riyad Mahrez inspired Leicester to a comfortable 3-0 home victory over Huddersfield.
Manchester City goalkeeper Ederson saved a 90th-minute penalty as Crystal Palace ended City's 18-game Premier League winning run in a dramatic 0-0 draw at Selhurst Park.
Arsene Wenger was denied victory in his 811th league game in charge of Arsenal as an 89th-minute penalty earned West Bromwich Albion a 1-1 draw at the Hawthorns.
Arsenal marked Arsene Wenger's record-equalling match as a Premier League manager by winning 3-2 at Crystal Palace.
Raheem Sterling fired Manchester City 15 points clear at the top of the Premier League table as they extended their winning run to 18 games at Newcastle.
Philippe Coutinho provided the style and compatriot Roberto Firmino the substance as Liverpool's brilliant Brazilians dispatched rudderless Swansea 5-0 in clinical fashion at Anfield.
Alvaro Morata returned from suspension to ignite Chelsea's 2-0 Premier League victory over Brighton at Stamford Bridge.
Jesse Lingard scored twice after coming on at half-time to help Manchester United salvage a 2-2 draw with Burnley at Old Trafford on Boxing Day.
Harry Kane smashed Alan Shearer's Premier League record for goals scored in a calendar year by hitting a hat trick in Tottenham's 5-2 mauling of Southampton.
Manchester United will spend Christmas an eye-watering 13 points behind runaway Premier League leaders Manchester City after Harry Maguire secured Leicester a draw with a last-gasp goal.
Harry Kane fired a hat trick to equal Alan Shearer's Premier League record of goals scored in a calendar year as Tottenham won 3-0 at Burnley.
Sergio Aguero took his tally of Etihad Stadium goals past 100 with a double as Premier League leaders Manchester City swept past Bournemouth 4-0.
Sam Allardyce's unbeaten run as Everton manager continued as Chelsea were held to a goalless draw at Goodison Park.
Liverpool fended off three goals in five minutes from Arsenal to salvage a 3-3 Premier League draw at the Emirates Stadium.
Bristol City sent Manchester United crashing out of the Carabao Cup after Korey Smith's stoppage-time strike secured a stunning 2-1 victory.
Alvaro Morata's stoppage-time strike sent Chelsea into the Carabao Cup semi-finals with a 2-1 defeat of Bournemouth.
Claudio Bravo was Manchester City's penalty hero as they kept their hopes of a dream quadruple alive to beat Leicester and reach the Carabao Cup semifinals.
Danny Welbeck scored the only goal of a forgettable game as Arsenal booked a place in the Carabao Cup semifinals at the expense of West Ham.
Liverpool had far too much attacking power for Bournemouth to withstand as they moved back into the top four with a 4-0 win at the Vitality Stadium.
Manchester United held on for a 2-1 win at West Bromwich Albion to cut neighbours Manchester City's lead at the top of the Premier League back to 11 points.
Leaders Manchester City powered to their 16th successive win in the Premier League with a 4-1 thrashing of Tottenham at the Etihad Stadium.
Arsenal returned to winning ways but had Mesut Ozil to thank for scoring a wonderful winner as they toiled against out-of-form Newcastle.
Time was on Chelsea's side as Marcos Alonso's free-kick earned a 1-0 Premier League win over Southampton.
Arsenal lost further ground on the Premier League leaders after they were held to a goalless draw at West Ham.
Tottenham climbed back into the Premier League's top four as Serge Aurier's fluke-goal and a header from Son Heung-min sealed a 2-0 victory over Brighton.
Liverpool manager Jurgen Klopp reunited the "Fab Four" but his prolific attacking quartet were all distinctly off-key as West Brom held out for a goalless draw at Anfield.
Manchester City set a new Premier League record of 15 consecutive wins with a 4-0 victory at bottom club Swansea.
Romelu Lukaku got a much-needed goal as Manchester United moved on from their galling derby defeat by beating Bournemouth.
Willian scored one and made two others as Chelsea finally turned in a display worthy of Premier League champions to win 3-1 at Huddersfield.
Runaway Premier League leaders Manchester City opened up an eye-watering double-digit lead over rivals Manchester United after Nicolas Otamendi fired Pep Guardiola's men to derby victory.
Manchester United were unable to match the intensity shown during Jose Mourinho's extraordinary pre-match press conference, but headers from Romelu Lukaku and Nemanja Matic saw them through to the FA Cup semi-finals at Brighton's expense.
Mohamed Salah's record-setting season shows no signs of slowing down as four goals in the 5-0 victory over Watford put him in pole position for the Premier League Golden Boot.
Tottenham Hotspur strolled into the semifinals of the FA Cup with a Christian Eriksen-inspired 3-0 victory over Swansea City.
David Silva struck twice as Manchester City took another stride towards their seemingly inevitable coronation as Premier League champions with a 2-0 victory at Stoke.
Tottenham Hotspur bounced back from their Champions League defeat to Juventus with a 4-1 win at Bournemouth in a game overshadowed by injury to Harry Kane.
Arsenal strolled to a much-needed win as Shkodran Mustafi, Pierre-Emerick Aubameyang and Henrikh Mkhitaryan saw off Watford 3-0 at the Emirates Stadium and Petr Cech kept his 200th Premier League clean sheet.
Two first-half goals gave Chelsea a 2-1 home victory over a Crystal Palace side whose relegation worries increase.
Everton registered a third successive victory at Goodison Park by beating Brighton 2-0.
Two goals from Marcus Rashford gave Manchester United a crucial 2-1 victory over Liverpool at Old Trafford, putting them five points clear of their rivals in second place in the Premier League.
Nemanja Matic struck in stoppage time as Manchester United came from two goals down to secure a vital 3-2 victory at Crystal Palace.
Bernardo Silva scored the only goal as Manchester City took another stride towards the Premier League title with a 1-0 victory over Chelsea.
Arsene Wenger remains under intense pressure as Arsenal were deservedly beaten 2-1 by Brighton & Hove Albion at the Amex Stadium on Sunday.
Tottenham warmed up for their Champions League tie with Juventus by easing to a 2-0 victory over Huddersfield at Wembley.
Mohamed Salah scored for the seventh successive match to continue a remarkable scoring spree that is the best in Europe as Liverpool comfortably beat Newcastle United 2-0.
Manchester City inflicted more pain on Arsene Wenger with a second crushing 3-0 victory over his Arsenal side in the space of four days.
Tottenham overcame Rochdale 6-1 in the FA Cup but video technology reduced the fifth-round replay at Wembley to a farce.
Swansea reached their first FA Cup quarterfinal since 1964 with a 2-0 home victory over Sheffield Wednesday.
Manchester City breezed past woeful Arsenal 3-0 to lift the Carabo Cup, Pep Guardiola's first trophy in English football, at Wembley.
Tottenham Hotspur grabbed an 89th-minute winner against Crystal Palace to move into fourth place after a determined home side had seemed set for a battling draw at Selhurst Park.
Substitute Jesse Lingard headed the winner as Manchester United came from a goal down to beat Chelsea 2-1 at Old Trafford and move back into second place in the Premier League.
Watford moved up to 10th in the table as Troy Deeney's late goal gave them a valuable 1-0 victory over Everton at Vicarage Road.
Liverpool took their goal tally for the season to 103 as they claimed second place in the Premier League with a comfortable 4-1 win over West Ham.
Stoke remain in the relegation zone after an error from goalkeeper Jack Butland meant they had to settle for a 1-1 draw at Leicester.
Manchester City's quadruple trophy bid was sensationally derailed by a shocking 1-0 defeat at third-division Wigan in the FA Cup fifth round on Monday.
Substitute Steve Davies earned Rochdale an FA Cup fifth-round replay at Wembley Stadium with his remarkable stoppage-time equaliser against Tottenham Hotspur at Spotland.
Manchester United overcame the video assistant referee's controversial intervention and reached the FA Cup quarterfinals thanks to Romelu Lukaku's brace at Huddersfield.
Willian dispatched two inch-perfect finishes as Chelsea cruised past Hull 4-0 and into the FA Cup quarter-finals.
Sheffield Wednesday fan Jamie Vardy put the Blades to the sword as Leicester knocked Sheffield United out of the FA Cup.
Chelsea eased the growing pressure on Antonio Conte and returned to the Premier League's top four with a convincing 3-0 win over West Brom.
Liverpool moved back above Tottenham and into third place in the Premier League table as two first-half goals gave them a routine 2-0 victory at struggling Southampton.