Premier League leading scorer Mohamed Salah had a rare off day as Liverpool continue to stumble towards guaranteeing a top-four finish after a goalless draw at home to Stoke.
Manchester City celebrated their title success in style with a resounding 5-0 win over Swansea at the Etihad Stadium.
Olivier Giroud proved the scourge of Southampton once again, setting Chelsea on course for FA Cup semifinal success and a mouth-watering clash with Manchester United.
A late flurry of goals saw Arsenal secure a 4-1 win over West Ham in their first game since Arsene Wenger revealed he is stepping down as boss.
Ander Herrera has Manchester United dreaming of FA Cup glory after Tottenham Hotspur again suffered semifinal sorrow.
A late strike from Salomon Rondon helped bottom-of-the-table West Bromwich Albion come from behind to draw 2-2 against Liverpool on Saturday at The Hawthorns.
Victor Moses was the match-winner as Chelsea eased the pressure on London rivals Arsenal by denting Burnley's surge for sixth place.
Southampton halted their losing run but a goalless draw at Leicester does little for their Premier League survival hopes.
Manchester United moved to within two points of securing a place in next season's Champions League with a 2-0 win at Bournemouth.
Tottenham's pursuit of Champions League football suffered a minor setback as they squandered a lead to draw 1-1 at Brighton.
Manchester United handed local rivals Manchester City the 2017-18 Premier League title after succumbing to a shock 1-0 defeat against West Bromwich Albion at Old Trafford that keeps the Baggies' slim survival hopes alive.
Arsenal's away woes in the Premier League continued on Sunday when they were beaten 2-1 by Newcastle United at St James' Park.
Mohamed Salah brought his remarkable goal tally to 40 in all competitions this season season by netting once more in a 3-0 win over Bournemouth.
Manchester City responded from a nightmare 10 days in style to put one hand on the Premier League title with a 3-1 win at Tottenham.
Olivier Giroud was the hero for Chelsea as the Blues fought back from two goals down to claim a 3-2 win over Premier League strugglers Southampton at St Mary's.
Javier Hernandez netted an equaliser for West Ham to thwart Chelsea again and dent their bid for Champions League football, while earning his side an important point in their bid to survive relegation in a 1-1 draw on Saturday.
Danny Welbeck scored twice as Arsenal deepened Southampton's relegation worries with a 3-2 win in a game that saw both sides reduced to 10 men in stoppage time at the Emirates Stadium.
Manchester United produced an incredible second-half comeback to beat rivals Manchester City 3-2 and leave them waiting for confirmation of the Premier League title after a thrilling game at the Etihad Stadium.
Christian Eriksen was credited with a brace as Harry Kane was denied a crucial goal in the Golden Boot race in Tottenham's 2-1 win over Stoke at the bet365 Stadium.
Everton and Liverpool had to settle for a share of the spoils as the Merseyside derby ended in a goalless stalemate at Goodison Park.
Dele Alli's double drove Tottenham to a first Stamford Bridge win over Chelsea since 1990 and left the Blues' Champions League qualification bid in tatters.
Arsenal scored three times in the last 15 minutes to condemn Premier League strugglers Stoke to defeat, despite a fairly positive showing from the Potters in north London.
Manchester City are just one win away from securing the Premier League title after a 3-1 victory over Everton at Goodison Park.
Romelu Lukaku's 100th Premier League goal set Manchester United on course for a comfortable victory against relegation-threatened Swansea.
Mohamed Salah's 37th goal of the season in all competitions handed Jurgen Klopp victory in his 100th Premier League match in charge of Liverpool.
Pedro's extra-time header saw Chelsea advance to the FA Cup semifinals at the expense of Leicester City.
Southampton are through to the FA Cup semi-finals for the first time in 15 years after a 2-0 victory over Wigan in Mark Hughes' first game in charge.
Manchester United were unable to match the intensity shown during Jose Mourinho's extraordinary pre-match press conference, but headers from Romelu Lukaku and Nemanja Matic saw them through to the FA Cup semi-finals at Brighton's expense.
Mohamed Salah's record-setting season shows no signs of slowing down as four goals in the 5-0 victory over Watford put him in pole position for the Premier League Golden Boot.
Tottenham Hotspur strolled into the semifinals of the FA Cup with a Christian Eriksen-inspired 3-0 victory over Swansea City.
Riyad Mahrez smashed a late penalty over the bar as Manchester City and Liverpool played out a dull 0-0 draw at Anfield.
Ross Barkley scored his first goal for Chelsea to help defeat Southampton 3-0 at St. Mary's on Sunday.
Arsenal midfielder Aaron Ramsey scored the goal of the game as Unai Emery's men made it nine consecutive wins in all competitions with this 5-1 victory over Fulham.
A 90th-minute goal by Alexis Sanchez helped Manchester United complete an unlikely comeback and claim a 3-2 win over Newcastle at Old Trafford on Saturday.
Eric Dier scored his first Premier League goal since April 2017 as Tottenham Hotspur defeated Cardiff City 1-0 at Wembley Stadium on Saturday.
Liverpool's unbeaten start to the Premier League season continued after Daniel Sturridge rescued a point in the dying minutes against Chelsea.
A late own goal from Watford's Craig Cathcart and a Mesut Ozil strike two minutes later gave Arsenal a 2-0 win at the Emirates on Saturday that sent them above the Hornets in the Premier League table.
Harry Kane scored twice as Tottenham Hotspur moved into fourth place in the Premier League with a 2-0 win at bottom club Huddersfield Town on Saturday.
A stunning Sergio Aguero goal capped Manchester City's 2-0 win over Brighton & Hove Albion as Pep Guardiola's champions served further notice that they will again be the side to beat in the Premier League this season.
Manchester United's miserable start to the season continued as they laboured to a 3-1 defeat at West Ham.
The brilliance of Chelsea's Eden Hazard ended Liverpool's 100 percent start to the season as Maurizio Sarri's side enjoyed a 2-1 win at Anfield in the League Cup third round on Wednesday.
Manchester City were made to work but found a way past Oxford United in a 3-0 Carabao Cup victory on Tuesday night.
Manchester United crashed out of the Carabao Cup with a defeat on penalties to Championship side Derby County on Tuesday after the third-round tie ended 2-2 in normal time at Old Trafford.
Two goals in three second-half minutes gave Arsenal a 2-0 victory over Everton at the Emirates Stadium and took them up to sixth in the Premier League table.
Chelsea were denied their sixth successive Premier League win as London rivals West Ham held them to a 0-0 draw at the London Stadium.
Tottenham Hotspur brought an end to a run of three successive defeats as they won 2-1 at Brighton on a damp Saturday evening on the south coast.
A disappointing Manchester United were held to a 1-1 draw at home to promoted Wolverhampton Wanderers at Old Trafford on Saturday, leaving them eight points adrift of Premier League leaders Liverpool.
Sergio Aguero marked his 300th appearance for Manchester City with a familiar landmark goal to set the resurgent Premier League champions on their way to a magnificent 5-0 win at Cardiff City on Saturday.
Liverpool forward Mohamed Salah netted his first league goal since Aug. 25 as the Reds thrashed Southampton 3-0 to make it six Premier League wins out of six and leapfrog Chelsea at the top of the table on Saturday.
West Ham United beat Everton 3-1 at Goodison Park on Sunday to secure their first Premier League points of the season as Marco Silva tasted defeat for the first time as Everton manager.
Manchester United ruined Watford's first perfect start to a Premier League season with a 2-1 victory at Vicarage Road on Saturday.
Manchester City comfortably defeated Fulham 3-0 at the Etihad Stadium on Saturday to stay within two points of leaders Liverpool and Chelsea.
A free kick by midfielder Granit Xhaka and a goal by Mesut Ozil gave Arsenal a 2-1 win at Newcastle United despite a stuttering first-half performance on Saturday.
A hat trick from Eden Hazard gave Chelsea their fifth win in five games, a 4-1 victory over Cardiff City that sent them to the top of the Premier League on Saturday.
Liverpool continued their perfect start to the season after a goal in each half gave them a 2-1 victory over Tottenham Hotspur at Wembley Stadium on Saturday.
Watford came from behind with two set-piece goals to beat Tottenham Hotspur 2-1 at Vicarage Road on Sunday, ending the visitors' perfect start to the Premier League season while maintaining their own.
Manchester United fans showed their backing for manager Jose Mourinho after Romelu Lukaku struck twice as United returned to winning ways after two successive Premier League losses with a 2-0 victory at Burnley on Sunday.
Alexandre Lacazette scored his first goal of the season in his first start under Unai Emery, handing Arsenal a 3-2 victory away against Cardiff City.
Raheem Sterling and Kyle Walker each scored as Manchester City defeated Newcastle United 2-1 at the Etihad Stadium on Saturday.
Chelsea stretched their perfect Premier League start to four games after second-half goals from substitute Pedro and Eden Hazard gave them a 2-0 home win over Bournemouth on Saturday.