Ashley Young fired Manchester United to a last-minute victory at Newcastle to maintain their charge for a top-four finish.
Tottenham got their top-four tilt back on track by overcoming Swansea 3-2 on a night when Bafetimbi Gomis' collapse had those inside White Hart Lane fearing the worst.
Stand-in captain Jordan Henderson led from the front with his second goal in successive matches as Liverpool maintained their pursuit of a top-four place.
David Silva and James Milner struck late in each half as under-fire reigning champions Manchester City grabbed a scrappy but much-needed 2-0 win over Leicester in the Premier League.
Jose Mourinho claimed the 21st trophy of his career as Chelsea overcame Tottenham with a clinical 2-0 victory in the Capital One Cup final at Wembley.
Arsenal recovered from their midweek European nightmare to beat Everton 2-0 at Emirates Stadium and move back to third in the Premier League.
Liverpool put a huge dent in Manchester City's title hopes with a 2-1 victory which dramatically enhanced their own hopes of a top-four finish.
Wayne Rooney scored his first league goals in over two months to give Manchester United a 2-0 victory over 10-man Sunderland.
Liverpool’s Jordan Henderson was delighted with what he believed was an amazing performance made by his side at St Mary’s Stadium after the Reds took out Southampton 2-0 in the Premier League.
Philippe Coutinho's exceptional strike amid a series of controversial decisions from referee Kevin Friend helped Liverpool overcome Southampton 2-0.
Manchester City warmed up for Tuesday's visit of Barcelona in style by crushing Newcastle 5-0 on a perfect day for the Premier League champions.
Arsenal moved up to third in the Premier League with a hard-fought 2-1 win at Crystal Palace.
Chelsea's troubled week ended in further controversy when Nemanja Matic was sent off as Burnley plundered a late 1-1 Premier League draw at Stamford Bridge.
Swansea completed their first-ever league double over Manchester United to dent the Red Devils' hopes of finishing in the Champions League places.
Wayne Rooney ended his goal drought as Manchester United came from behind to beat Preston and set up a mouth-watering FA Cup quarter-final against Arsenal.
Olivier Giroud struck twice as FA Cup holders Arsenal beat Middlesbrough 2-0 at the Emirates Stadium to book their place in the quarterfinals.
Liverpool exorcised some demons at Selhurst Park by reaching the FA Cup quarterfinals with an impressive win against Crystal Palace.
Willian struck an 89th-minute winner as Chelsea beat Everton 1-0 but the Premier League leaders could face disciplinary action once more after Branislav Ivanovic appeared to headbutt James McCarthy.
Sergio Aguero and Manchester City rediscovered their touch as the champions turned on the style in the second half to win 4-1 at Stoke.
Manchester United cut out the long-ball tactics but they still had to battle their way to a 3-1 win over Burnley at Old Trafford.
Liverpool's Mario Balotelli picked the perfect time to score his first Premier League goal for the club as he stole the headlines from the battle between England strikers present and, potentially, future.
Arsenal moved back into the Premier League top four as they edged out bottom club Leicester 2-1 at the Emirates Stadium.
West Ham were denied a first Premier League win over Manchester United in seven years and 13 attempts by Daley Blind's stoppage-time strike.
Even the occasion of his final Premier League Merseyside derby could not inspire Liverpool captain Steven Gerrard to more heroics as the 224th meeting of the clubs disappointingly finished goalless.
Branislav Ivanovic's rocket gave Chelsea a crucial 2-1 win at Aston Villa - despite the hosts ending their 11-hour goal drought.
Substitute James Milner struck a superb injury-time free-kick as lacklustre champions Manchester City rescued a point with a 1-1 draw against Hull.
Harry Kane inspired boyhood club Tottenham to victory over Arsenal in a wonderfully frantic and frenetic north London derby.
Philippe Coutinho celebrated his new five-year contract with an added-time winner as Liverpool kept their FA Cup hopes alive in a dramatic late turnaround at Bolton.
Manchester United overcame Cambridge United in their FA Cup replay on Tuesday, winning 3-0 less than two weeks after a humbling 0-0 draw.
Juan Cuadrado has completed his move from Fiorentina to Chelsea for a total fee of 35 million euros, including bonuses, although Italy's prime minister Matteo Renzi does not approve of the transfer.
Liverpool had far too much attacking power for Bournemouth to withstand as they moved back into the top four with a 4-0 win at the Vitality Stadium.
Manchester United held on for a 2-1 win at West Bromwich Albion to cut neighbours Manchester City's lead at the top of the Premier League back to 11 points.
Leaders Manchester City powered to their 16th successive win in the Premier League with a 4-1 thrashing of Tottenham at the Etihad Stadium.
Arsenal returned to winning ways but had Mesut Ozil to thank for scoring a wonderful winner as they toiled against out-of-form Newcastle.
Time was on Chelsea's side as Marcos Alonso's free-kick earned a 1-0 Premier League win over Southampton.
Arsenal lost further ground on the Premier League leaders after they were held to a goalless draw at West Ham.
Tottenham climbed back into the Premier League's top four as Serge Aurier's fluke-goal and a header from Son Heung-min sealed a 2-0 victory over Brighton.
Liverpool manager Jurgen Klopp reunited the "Fab Four" but his prolific attacking quartet were all distinctly off-key as West Brom held out for a goalless draw at Anfield.
Manchester City set a new Premier League record of 15 consecutive wins with a 4-0 victory at bottom club Swansea.
Romelu Lukaku got a much-needed goal as Manchester United moved on from their galling derby defeat by beating Bournemouth.
Willian scored one and made two others as Chelsea finally turned in a display worthy of Premier League champions to win 3-1 at Huddersfield.
Runaway Premier League leaders Manchester City opened up an eye-watering double-digit lead over rivals Manchester United after Nicolas Otamendi fired Pep Guardiola's men to derby victory.
Wayne Rooney's first Merseyside derby goal earned Everton a 1-1 draw at Anfield as Liverpool manager Jurgen Klopp's selection gamble backfired.
Olivier Giroud climbed off the bench to rescue a point for Arsenal in a 1-1 draw at Southampton.
Ayoze Perez's late own goal cost Newcastle a precious Premier League draw as Leicester ruined the Magpies' 125th birthday celebrations.
Tottenham ended a four-match Premier League winless streak in style with Harry Kane scoring a brace as they thrashed Stoke 5-1 at Wembley.
Marko Arnautovic's first West Ham goal secured a 1-0 victory over Chelsea and a first win for manager David Moyes.
Manchester City left it late for the third game in a row as they beat West Ham United 2-1 at the Etihad Stadium thanks to David Silva's strike and extended their Premier League lead.
Bournemouth and Southampton shared the spoils as an entertaining match on the south coast finished in a 1-1 draw.
Jesse Lingard scored twice but Paul Pogba was sent off as Manchester United beat Arsenal 3-1 in a breathless match at the Emirates Stadium.
Talk of Burnley qualifying for Europe was dealt a sobering blow with defeat at improving Leicester.
Gylfi Sigurdsson and Dominic Calvert-Lewin scored second-half goals as Sam Allardyce's first game in charge of Everton ended in a 2-0 home win over Huddersfield.
Davinson Sanchez's red card forced Tottenham to fight for a 1-1 draw at Watford, toughening their battle to climb back into the Premier League's top four.
Philippe Coutinho and Roberto Firmino demolished Brighton to keep Liverpool's top-four charge on track.
A sparkling two-goal performance from Eden Hazard helped Chelsea come from a goal down to beat Newcastle 3-1 at Stamford Bridge and go level on points with second-placed Manchester United.
Substitute Mohamed Salah's purple patch continued with two more goals as Liverpool ground out a controversial 3-0 win at Stoke.
Raheem Sterling scored a dramatic winner as Manchester City maintained their winning run with a last-gasp 2-1 defeat of Southampton.
Antonio Conte was sent off as Chelsea claimed a fifth Premier League win in six games with a 1-0 defeat of Swansea.
Arsenal strengthened their position in the Premier League top four as they made light work of Huddersfield to maintain their healthy home form.
Newcastle ended a run of four straight defeats after coming back from 2-0 down to claim a gutsy point at West Brom.