Shkodran Mustafi's header saw Valencia get back to winning ways in a hard-fought Primera Division clash with Granada.
Mathieu Flamini struck twice as Arsenal beat north London rivals Tottenham 2-1 in the third round of the Capital One Cup at White Hart Lane.
Anthony Martial stepped off the bench and scored his fourth goal in four matches as Manchester United strolled into the fourth round of the Capital One Cup with a 3-0 win over Ipswich.
Chelsea continued to rebuild their season as they eased past Walsall in the Capital One Cup.
Liverpool manager Brendan Rodgers' torturous season continued as they scraped through a Capital One Cup tie on penalties against League Two Carlisle.
Everton reached the fourth round of the Capital One Cup after a deserved 2-1 defeat of Championship opponents Reading.
Kevin De Bruyne and Raheem Sterling were on top-form as Manchester City cruised to a 4-1 Capital One Cup victory at Sunderland to end a two-game losing run in explosive fashion.
Anthony Martial struck twice to make it three goals in two games for Manchester United as Louis van Gaal's men came from behind to beat Southampton 3-2 at St Mary's.
Liverpool's Danny Ings scored within two minutes of coming on -- but his side were held 1-1 by Norwich at Anfield.
Tottenham earned their first home win of the Premier League season with a convincing 1-0 defeat of Crystal Palace.
West Ham withstood a barrage of second-half pressure to condemn Manchester City to their first defeat of the Premier League season.
Gabriel Paulista and Santi Cazorla were both sent off for Arsenal as Chelsea clinched a 2-0 win over their Premier League rivals.
Ryan Mason fired Tottenham to their first Premier League victory of the season as Sunderland were made to wait for theirs.
Anthony Martial scored on his Manchester United debut to seal a 3-1 win over rivals Liverpool as goalkeeper David De Gea made his comeback.
Kelechi Iheanacho scored a dramatic late winner within seconds of coming on against Crystal Palace to preserve Manchester City's 100 percent record in the Premier League.
Goals from Theo Walcott and Olivier Giroud earned Arsenal a 2-0 win over Stoke, but it should have been far more convincing for Arsene Wenger's side.
Steven Naismith struck a brilliant hat trick as stuttering Premier League champions Chelsea crashed to a 3-1 defeat at Everton.
Manchester United goalkeeper David De Gea has signed a four-year contract extension less than two weeks after a proposed move to Real Madrid collapsed on transfer deadline day.
Manchester United have completed the signing of forward Anthony Martial from Monaco.
Two goals in five minutes saw Swansea beat Manchester United at the Liberty Stadium. Juan Mata gave the hosts the lead before Andre Ayew equalised and Bafetimbi Gomis netted the winner.
Manchester City have signed Kevin De Bruyne from Wolfsburg for around £54 million.
Tim Howard denied Tottenham their first Premier League win of the season with a string of superb saves that enabled Everton to leave White Hart Lane with a goalless draw.
Liverpool endured a miserable afternoon as they slumped to a 3-0 home defeat to West Ham United and saw Philippe Coutinho sent off.
Chelsea's poor start to the season continued as they lost 2-1 at home to Crystal Palace.
Raheem Sterling struck his first Manchester City goal as Manuel Pellegrini's men maintained their flying Barclays Premier League start with a 2-0 win over Watford.
Fabricio Coloccini's own goal handed Arsenal a hard-fought victory at Newcastle after Aleksandar Mitrovic was sent off just 16 minutes into the game.
Arsenal will travel to Tottenham in the stand-out tie of a strong Capital One Cup third-round draw.
Both Arsenal and Liverpool enjoyed a half of dominance at the Emirates Stadium on Monday - but neither side could find a winning goal to take the three points.
Aleksandar Kolarov and Samir Nasri struck in the second half as Manchester City maintained their winning to the season with a 2-0 victory at Everton.
Pedro Rodriguez struck a debut Chelsea goal to inspire the champions to their first win of the season at West Brom as John Terry's difficult campaign continued.
Manchester City's quadruple trophy bid was sensationally derailed by a shocking 1-0 defeat at third-division Wigan in the FA Cup fifth round on Monday.
Substitute Steve Davies earned Rochdale an FA Cup fifth-round replay at Wembley Stadium with his remarkable stoppage-time equaliser against Tottenham Hotspur at Spotland.
Manchester United overcame the video assistant referee's controversial intervention and reached the FA Cup quarterfinals thanks to Romelu Lukaku's brace at Huddersfield.
Willian dispatched two inch-perfect finishes as Chelsea cruised past Hull 4-0 and into the FA Cup quarter-finals.
Sheffield Wednesday fan Jamie Vardy put the Blades to the sword as Leicester knocked Sheffield United out of the FA Cup.
Chelsea eased the growing pressure on Antonio Conte and returned to the Premier League's top four with a convincing 3-0 win over West Brom.
Liverpool moved back above Tottenham and into third place in the Premier League table as two first-half goals gave them a routine 2-0 victory at struggling Southampton.
Matt Ritchie scored a second-half winner for Newcastle as they lifted themselves out of the relegation places with a 1-0 victory over Manchester United at St James' Park.
Sergio Aguero scored four times as Manchester City extended their Premier League lead to 16 points with a 5-1 demolition of Leicester at the Etihad Stadium.
Everton's Sam Allardyce won the battle of ex-England managers at Goodison Park to ease growing pressure with a 3-1 victory over Roy Hodgson's struggling Crystal Palace.
Harry Kane proved Arsenal's nemesis again as his bullet header earned Tottenham a deserved 1-0 victory in the North London derby.
Erik Lamela scored his first goal in 17 months as Tottenham sauntered past Newport and into the fifth round of the FA Cup.
Swansea recorded their biggest-ever FA Cup win as Notts County were demolished 8-1 at the Liberty Stadium.
Antonio Conte's future as Chelsea boss was cast into further doubt as his 10 men were thrashed 4-1 by Watford on Monday night.
Mohamed Salah and Harry Kane traded stoppage-time goals as Liverpool and Tottenham drew 2-2 in a wild affair at Anfield on Sunday.
Newcastle resisted intense pressure from Crystal Palace to earn a 1-1 draw at Selhurst Park that again took them clear of the bottom three.
`Aaron Ramsey hit a hat trick with Arsenal fans treated to their first showing of their January transfers in tandem as both Henrikh Mkhitaryan and Pierre-Emerick Aubameyang shone in a comfortable 5-1 win over Everton.
Alexis Sanchez's first goal for Manchester United wrapped up a 2-0 victory against Huddersfield on a day when the clubs came together to remember those who lost their lives in the Munich air disaster.
Swansea's resurgence continued as they climbed out of the Premier League relegation zone with a 1-1 draw at Leicester, who were again without want-away midfielder Riyad Mahrez.
Johann Berg Gudmundsson struck a late equaliser as Burnley grabbed a 1-1 draw against Premier League leaders Manchester City at Turf Moor.
Christian Eriksen scored within 11 seconds as Tottenham brushed aside a below-par Manchester United to seal a crunch 2-0 victory in the race for the top four.
Kevin De Bruyne was again the inspiration as Manchester City opened up a 15-point lead at the top of the Premier League with a 3-0 win over West Brom.
Theo Walcott's maiden Everton goals secured a first win in eight matches as a 2-1 triumph over Leicester arrested their slide under Sam Allardyce.
Bournemouth scored three goals in 16 remarkable second-half minutes to record a sensational 3-0 victory against Chelsea at Stamford Bridge on Wednesday evening.
Arsenal have completed the signing of striker Pierre-Emerick Aubameyang from Borussia Dortmund for a fee of €63.75 million (£56m).
Chelsea have completed the signing of Olivier Giroud from Arsenal for a reported £16.25 million on an 18-month contract.
Tottenham Hotspur have completed the signing of winger Lucas Moura from Paris Saint-Germain for a fee of в‚¬28 million.
Liverpool bounced back to winning ways in the Premier League and maintained their Champions League challenge with a 3-0 win at Huddersfield.
Swansea climbed out of the relegation zone for the first time in three months as Petr Cech's dreadful howler helped condemn Arsenal to a 3-1 defeat at the Liberty Stadium.
Two first-half goals were enough to see Manchester City comfortably through to the FA Cup fifth round at Championship side Cardiff City.