Jose Mourinho's position as Chelsea boss appears ever more precarious after Jurgen Klopp's Liverpool inflicted Chelsea's sixth defeat in 11 Premier League games.
Wayne Rooney, Michael Carrick and Ashley Young all missed penalties as Middlesbrough knocked Manchester United out of the Capital One Cup on penalties at Old Trafford.
Wilfried Bony and Kelechi Iheanacho were among the goalscorers as Manchester City eased into the Capital One Cup quarterfinals with a 5-1 win over Crystal Palace.
Jurgen Klopp's first victory as Liverpool manager was secured via the unlikeliest of sources as defender Nathaniel Clyne scored the only goal to beat Bournemouth 1-0.
The pressure on Jose Mourinho cranked up another notch as holders Chelsea crashed out of the Capital One Cup with a 5-4 loss on penalties at 10-man Stoke following a 1-1 draw after 120 minutes.
Arsenal were unceremoniously dumped out of the Capital One Cup on a damaging night as Sheffield Wednesday blew them away with a stunning 3-0 victory at Hillsborough.
Southampton's Sadio Mane scored late to deny Jurgen Klopp his first win as Liverpool manager, with Sunday's Premier League match finishing 1-1.
Harry Kane returned to form as he struck a hat trick to sink sorry Bournemouth in the Premier League on Sunday.
Manchester City moved to the top of the Premier League despite a dull goalless draw in the Manchester derby at Old Trafford.
Arsenal moved to the top of the Premier League following a hard-earned 2-1 win over Everton at the Emirates Stadium.
Chelsea slumped to their fifth defeat of the Premier League season amid controversial scenes as West Ham won 2-1 at Upton Park.
Georginio Wijnaldum hit Norwich for four as Newcastle finally ended their wait for a Premier League victory at the ninth attempt with a 6-2 win on Sunday.
Arsenal moved to second in the Premier League with an impressive 3-0 win at Watford.
Wayne Rooney scored his first goal at Goodison Park for eight years as Manchester United coasted to a 3-0 victory on an emotional afternoon for Everton.
Raheem Sterling hit a first-half hat-trick and Wilfried Bony struck twice as Barclays Premier League leaders Manchester City overcame promoted Bournemouth 5-1 at the Etihad Stadium.
Diego Costa eased Chelsea manager Jose Mourinho's concerns as Aston Villa's hapless defenders heaped more misery on Tim Sherwood at Stamford Bridge.
Jurgen Klopp, the self-proclaimed "Normal One," left White Hart Lane with what he labelled a "normal result" as his new Liverpool side drew 0-0 with Tottenham.
Cristiano Ronaldo became Real Madrid's all-time top scorer as Rafael Benitez's side saw off Levante 3-0 to go top of the Primera Division.
Liverpool have confirmed the appointment of Jurgen Klopp as their new manager to replace Brendan Rodgers.
Liverpool sacked manager Brendan Rodgers on Sunday, with the decision coming just hours after a 1-1 Merseyside derby draw at Everton.
Alexis Sanchez's stunning first-half brace helped Arsenal blow away Manchester United 3-0 at the Emirates Stadium to move second in the Premier League.
Christian Eriksen stunned Swansea with two brilliant free kicks after Tottenham striker Harry Kane had scored a spectacular own goal.
Liverpool manager Brendan Rodgers maintained his unbeaten record in Merseyside derbies but could not keep his job as he was sacked after his side managed a 1-1 draw at Everton.
Chelsea capitulated and were booed off as Southampton won at Stamford Bridge for the first time in almost 14 years to leave Jose Mourinho contemplating a fourth loss from eight Premier League games this season.
Sergio Aguero scored five goals in a sensational 20-minute spell as Manchester City came from behind to crush Newcastle 6-1 in the Premier League.
Substitutes Ramires and Willian got Chelsea out of jail as they fought back from 2-0 down at Newcastle to snatch a point.
Wayne Rooney ended his 11-match goal drought as Manchester United climbed to the top of the Premier League for the first time in over two years with victory over Sunderland.
Arsenal came from behind to beat Leicester 5-2 on the road thanks to a hat trick from Alexis Sanchez.
Liverpool overcame Aston Villa with a 3-2 win in a thriller at Anfield.
Harry Kane netted his first Tottenham goal in over 640 minutes of football as he helped Tottenham come from behind to beat Premier League leaders Manchester City 4-1 at White Hart Lane.
Manchester City's quadruple trophy bid was sensationally derailed by a shocking 1-0 defeat at third-division Wigan in the FA Cup fifth round on Monday.
Substitute Steve Davies earned Rochdale an FA Cup fifth-round replay at Wembley Stadium with his remarkable stoppage-time equaliser against Tottenham Hotspur at Spotland.
Manchester United overcame the video assistant referee's controversial intervention and reached the FA Cup quarterfinals thanks to Romelu Lukaku's brace at Huddersfield.
Willian dispatched two inch-perfect finishes as Chelsea cruised past Hull 4-0 and into the FA Cup quarter-finals.
Sheffield Wednesday fan Jamie Vardy put the Blades to the sword as Leicester knocked Sheffield United out of the FA Cup.
Chelsea eased the growing pressure on Antonio Conte and returned to the Premier League's top four with a convincing 3-0 win over West Brom.
Liverpool moved back above Tottenham and into third place in the Premier League table as two first-half goals gave them a routine 2-0 victory at struggling Southampton.
Matt Ritchie scored a second-half winner for Newcastle as they lifted themselves out of the relegation places with a 1-0 victory over Manchester United at St James' Park.
Sergio Aguero scored four times as Manchester City extended their Premier League lead to 16 points with a 5-1 demolition of Leicester at the Etihad Stadium.
Everton's Sam Allardyce won the battle of ex-England managers at Goodison Park to ease growing pressure with a 3-1 victory over Roy Hodgson's struggling Crystal Palace.
Harry Kane proved Arsenal's nemesis again as his bullet header earned Tottenham a deserved 1-0 victory in the North London derby.
Erik Lamela scored his first goal in 17 months as Tottenham sauntered past Newport and into the fifth round of the FA Cup.
Swansea recorded their biggest-ever FA Cup win as Notts County were demolished 8-1 at the Liberty Stadium.
Antonio Conte's future as Chelsea boss was cast into further doubt as his 10 men were thrashed 4-1 by Watford on Monday night.
Mohamed Salah and Harry Kane traded stoppage-time goals as Liverpool and Tottenham drew 2-2 in a wild affair at Anfield on Sunday.
Newcastle resisted intense pressure from Crystal Palace to earn a 1-1 draw at Selhurst Park that again took them clear of the bottom three.
`Aaron Ramsey hit a hat trick with Arsenal fans treated to their first showing of their January transfers in tandem as both Henrikh Mkhitaryan and Pierre-Emerick Aubameyang shone in a comfortable 5-1 win over Everton.
Alexis Sanchez's first goal for Manchester United wrapped up a 2-0 victory against Huddersfield on a day when the clubs came together to remember those who lost their lives in the Munich air disaster.
Swansea's resurgence continued as they climbed out of the Premier League relegation zone with a 1-1 draw at Leicester, who were again without want-away midfielder Riyad Mahrez.
Johann Berg Gudmundsson struck a late equaliser as Burnley grabbed a 1-1 draw against Premier League leaders Manchester City at Turf Moor.
Christian Eriksen scored within 11 seconds as Tottenham brushed aside a below-par Manchester United to seal a crunch 2-0 victory in the race for the top four.
Kevin De Bruyne was again the inspiration as Manchester City opened up a 15-point lead at the top of the Premier League with a 3-0 win over West Brom.
Theo Walcott's maiden Everton goals secured a first win in eight matches as a 2-1 triumph over Leicester arrested their slide under Sam Allardyce.
Bournemouth scored three goals in 16 remarkable second-half minutes to record a sensational 3-0 victory against Chelsea at Stamford Bridge on Wednesday evening.
Arsenal have completed the signing of striker Pierre-Emerick Aubameyang from Borussia Dortmund for a fee of €63.75 million (£56m).
Chelsea have completed the signing of Olivier Giroud from Arsenal for a reported £16.25 million on an 18-month contract.
Tottenham Hotspur have completed the signing of winger Lucas Moura from Paris Saint-Germain for a fee of в‚¬28 million.
Liverpool bounced back to winning ways in the Premier League and maintained their Champions League challenge with a 3-0 win at Huddersfield.
Swansea climbed out of the relegation zone for the first time in three months as Petr Cech's dreadful howler helped condemn Arsenal to a 3-1 defeat at the Liberty Stadium.
Two first-half goals were enough to see Manchester City comfortably through to the FA Cup fifth round at Championship side Cardiff City.