Georginio Wijnaldum handed under-pressure head coach Steve McClaren some welcome relief as Newcastle beat in-form Liverpool.
Chelsea were plunged into crisis once more as Bournemouth claimed the biggest win of their Premier League campaign with a 1-0 win at Stamford Bridge.
Manchester United were booed off yet again as they played out their sixth goalless draw of the season against West Ham.
Arsenal were not at their free-flowing best against Sunderland, but still produced a match-winning performance that moved them up to second in the Premier League.
Tottenham extended their unbeaten run to 14 games to set a new club record in the Premier League as they were held 1-1 at West Brom.
Leicester returned to the top of the Premier League with a handsome 3-0 victory at Swansea -- and this time they did not even need a Jamie Vardy goal to do it.
Stoke duo Marko Arnautovic and Xherdan Shaqiri tore Manchester City to shreds in a brilliant first-half display that made Manuel Pellegrini's side look anything but Premier League leaders.
Liverpool cruised into the semifinals of the Capital One Cup as fit-again Daniel Sturridge inspired a stunning 6-1 win at Southampton.
Manchester City booked their place in the Capital One Cup semifinals, but the 4-1 scoreline flatted them somewhat against Championship side Hull.
Gerard Deulofeu turned in a masterclass to send Everton into the Capital One Cup semisfinals and fulfil Middlesbrough boss Aitor Karanka's prophecy.
Arsenal's title ambitions suffered a double-blow on Sunday as a draw at Norwich was compounded by an injury to Alexis Sanchez.
James Milner's second-half penalty secured a first home league win for Liverpool manager Jurgen Klopp as they edged past Swansea 1-0.
Diego Costa was dropped as Chelsea and Tottenham played out a goalless draw which will do little to kick-start the Premier League champions' season.
Jamie Vardy set a new Premier League record for scoring in consecutive matches, but Leicester City had to settle for a draw at home to Manchester United.
Sergio Aguero limped off but Manchester City survived a Southampton fightback to get back to winning ways and the top of the table with a 3-1 win at the Etihad Stadium.
Tottenham demonstrated their Champions League credentials with a convincing 4-1 Premier League defeat of West Ham at White Hart Lane on Saturday.
Liverpool shocked Manchester City with three first-half goals at the Etihad Stadium to earn a 4-1 win against Manuel Pellegrini's Premier League title contenders.
Santi Cazorla missed a late penalty as Arsenal blew the chance to go top of the Premier League with a 2-1 defeat at West Brom.
Jose Mourinho was back in the dugout and Diego Costa returned to the score sheet as Chelsea claimed a much-needed 1-0 win over Norwich.
Troy Deeney went from hero to villain in the space of five minutes as the Watford striker scored a late penalty and then an own goal to give Manchester United a 2-1 victory at Vicarage Road.
Arsenal missed the chance to go top of the Premier League as they were held to a 1-1 draw by Tottenham in Sunday's North London derby at the Emirates Stadium.
Scott Dann ended Jurgen Klopp's unbeaten start as Liverpool manager with a late header which gave a vibrant Crystal Palace their third successive Premier League victory over the Reds.
Aston Villa claimed a vital point in their survival fight as they held Manchester City in Remi Garde's first game in charge.
Chelsea suffered a third straight Barclays Premier League defeat as they were beaten 1-0 at Stoke to heap the pressure back on their absent manager Jose Mourinho.
Jesse Lingard gave the home support inside Old Trafford something to cheer as he helped Manchester United to a 2-0 victory over 10-man West Brom with his first goal for the club.
New Aston Villa manager Remi Garde watched his team lose 3-1 at White Hart Lane on Monday night as Tottenham moved up to fifth in the Premier League table.
Arouna Kone's hat trick saw Everton rack up their biggest Premier League win in eight years with as they demolished Sunderland 6-2 at Goodison Park.
Manchester United lost ground in the race for the Premier League title with a 0-0 draw at Crystal Palace that could easily have ended in defeat.
Arsenal made light of their injury problems with a comprehensive 3-0 Premier League win at Swansea.
Yaya Toure struck a late penalty winner as Premier League leaders Manchester City snatched a dramatic 2-1 win over 10-man Norwich.
Manchester City's quadruple trophy bid was sensationally derailed by a shocking 1-0 defeat at third-division Wigan in the FA Cup fifth round on Monday.
Substitute Steve Davies earned Rochdale an FA Cup fifth-round replay at Wembley Stadium with his remarkable stoppage-time equaliser against Tottenham Hotspur at Spotland.
Manchester United overcame the video assistant referee's controversial intervention and reached the FA Cup quarterfinals thanks to Romelu Lukaku's brace at Huddersfield.
Willian dispatched two inch-perfect finishes as Chelsea cruised past Hull 4-0 and into the FA Cup quarter-finals.
Sheffield Wednesday fan Jamie Vardy put the Blades to the sword as Leicester knocked Sheffield United out of the FA Cup.
Chelsea eased the growing pressure on Antonio Conte and returned to the Premier League's top four with a convincing 3-0 win over West Brom.
Liverpool moved back above Tottenham and into third place in the Premier League table as two first-half goals gave them a routine 2-0 victory at struggling Southampton.
Matt Ritchie scored a second-half winner for Newcastle as they lifted themselves out of the relegation places with a 1-0 victory over Manchester United at St James' Park.
Sergio Aguero scored four times as Manchester City extended their Premier League lead to 16 points with a 5-1 demolition of Leicester at the Etihad Stadium.
Everton's Sam Allardyce won the battle of ex-England managers at Goodison Park to ease growing pressure with a 3-1 victory over Roy Hodgson's struggling Crystal Palace.
Harry Kane proved Arsenal's nemesis again as his bullet header earned Tottenham a deserved 1-0 victory in the North London derby.
Erik Lamela scored his first goal in 17 months as Tottenham sauntered past Newport and into the fifth round of the FA Cup.
Swansea recorded their biggest-ever FA Cup win as Notts County were demolished 8-1 at the Liberty Stadium.
Antonio Conte's future as Chelsea boss was cast into further doubt as his 10 men were thrashed 4-1 by Watford on Monday night.
Mohamed Salah and Harry Kane traded stoppage-time goals as Liverpool and Tottenham drew 2-2 in a wild affair at Anfield on Sunday.
Newcastle resisted intense pressure from Crystal Palace to earn a 1-1 draw at Selhurst Park that again took them clear of the bottom three.
`Aaron Ramsey hit a hat trick with Arsenal fans treated to their first showing of their January transfers in tandem as both Henrikh Mkhitaryan and Pierre-Emerick Aubameyang shone in a comfortable 5-1 win over Everton.
Alexis Sanchez's first goal for Manchester United wrapped up a 2-0 victory against Huddersfield on a day when the clubs came together to remember those who lost their lives in the Munich air disaster.
Swansea's resurgence continued as they climbed out of the Premier League relegation zone with a 1-1 draw at Leicester, who were again without want-away midfielder Riyad Mahrez.
Johann Berg Gudmundsson struck a late equaliser as Burnley grabbed a 1-1 draw against Premier League leaders Manchester City at Turf Moor.
Christian Eriksen scored within 11 seconds as Tottenham brushed aside a below-par Manchester United to seal a crunch 2-0 victory in the race for the top four.
Kevin De Bruyne was again the inspiration as Manchester City opened up a 15-point lead at the top of the Premier League with a 3-0 win over West Brom.
Theo Walcott's maiden Everton goals secured a first win in eight matches as a 2-1 triumph over Leicester arrested their slide under Sam Allardyce.
Bournemouth scored three goals in 16 remarkable second-half minutes to record a sensational 3-0 victory against Chelsea at Stamford Bridge on Wednesday evening.
Arsenal have completed the signing of striker Pierre-Emerick Aubameyang from Borussia Dortmund for a fee of €63.75 million (£56m).
Chelsea have completed the signing of Olivier Giroud from Arsenal for a reported £16.25 million on an 18-month contract.
Tottenham Hotspur have completed the signing of winger Lucas Moura from Paris Saint-Germain for a fee of в‚¬28 million.
Liverpool bounced back to winning ways in the Premier League and maintained their Champions League challenge with a 3-0 win at Huddersfield.
Swansea climbed out of the relegation zone for the first time in three months as Petr Cech's dreadful howler helped condemn Arsenal to a 3-1 defeat at the Liberty Stadium.
Two first-half goals were enough to see Manchester City comfortably through to the FA Cup fifth round at Championship side Cardiff City.