Aston Villa claimed a vital point in their survival fight as they held Manchester City in Remi Garde's first game in charge.
Chelsea suffered a third straight Barclays Premier League defeat as they were beaten 1-0 at Stoke to heap the pressure back on their absent manager Jose Mourinho.
Jesse Lingard gave the home support inside Old Trafford something to cheer as he helped Manchester United to a 2-0 victory over 10-man West Brom with his first goal for the club.
New Aston Villa manager Remi Garde watched his team lose 3-1 at White Hart Lane on Monday night as Tottenham moved up to fifth in the Premier League table.
Arouna Kone's hat trick saw Everton rack up their biggest Premier League win in eight years with as they demolished Sunderland 6-2 at Goodison Park.
Manchester United lost ground in the race for the Premier League title with a 0-0 draw at Crystal Palace that could easily have ended in defeat.
Arsenal made light of their injury problems with a comprehensive 3-0 Premier League win at Swansea.
Yaya Toure struck a late penalty winner as Premier League leaders Manchester City snatched a dramatic 2-1 win over 10-man Norwich.
Jose Mourinho's position as Chelsea boss appears ever more precarious after Jurgen Klopp's Liverpool inflicted Chelsea's sixth defeat in 11 Premier League games.
Wayne Rooney, Michael Carrick and Ashley Young all missed penalties as Middlesbrough knocked Manchester United out of the Capital One Cup on penalties at Old Trafford.
Wilfried Bony and Kelechi Iheanacho were among the goalscorers as Manchester City eased into the Capital One Cup quarterfinals with a 5-1 win over Crystal Palace.
Jurgen Klopp's first victory as Liverpool manager was secured via the unlikeliest of sources as defender Nathaniel Clyne scored the only goal to beat Bournemouth 1-0.
The pressure on Jose Mourinho cranked up another notch as holders Chelsea crashed out of the Capital One Cup with a 5-4 loss on penalties at 10-man Stoke following a 1-1 draw after 120 minutes.
Arsenal were unceremoniously dumped out of the Capital One Cup on a damaging night as Sheffield Wednesday blew them away with a stunning 3-0 victory at Hillsborough.
Southampton's Sadio Mane scored late to deny Jurgen Klopp his first win as Liverpool manager, with Sunday's Premier League match finishing 1-1.
Harry Kane returned to form as he struck a hat trick to sink sorry Bournemouth in the Premier League on Sunday.
Manchester City moved to the top of the Premier League despite a dull goalless draw in the Manchester derby at Old Trafford.
Arsenal moved to the top of the Premier League following a hard-earned 2-1 win over Everton at the Emirates Stadium.
Chelsea slumped to their fifth defeat of the Premier League season amid controversial scenes as West Ham won 2-1 at Upton Park.
Georginio Wijnaldum hit Norwich for four as Newcastle finally ended their wait for a Premier League victory at the ninth attempt with a 6-2 win on Sunday.
Arsenal moved to second in the Premier League with an impressive 3-0 win at Watford.
Wayne Rooney scored his first goal at Goodison Park for eight years as Manchester United coasted to a 3-0 victory on an emotional afternoon for Everton.
Raheem Sterling hit a first-half hat-trick and Wilfried Bony struck twice as Barclays Premier League leaders Manchester City overcame promoted Bournemouth 5-1 at the Etihad Stadium.
Diego Costa eased Chelsea manager Jose Mourinho's concerns as Aston Villa's hapless defenders heaped more misery on Tim Sherwood at Stamford Bridge.
Jurgen Klopp, the self-proclaimed "Normal One," left White Hart Lane with what he labelled a "normal result" as his new Liverpool side drew 0-0 with Tottenham.
Cristiano Ronaldo became Real Madrid's all-time top scorer as Rafael Benitez's side saw off Levante 3-0 to go top of the Primera Division.
Liverpool have confirmed the appointment of Jurgen Klopp as their new manager to replace Brendan Rodgers.
Liverpool sacked manager Brendan Rodgers on Sunday, with the decision coming just hours after a 1-1 Merseyside derby draw at Everton.
Alexis Sanchez's stunning first-half brace helped Arsenal blow away Manchester United 3-0 at the Emirates Stadium to move second in the Premier League.
Christian Eriksen stunned Swansea with two brilliant free kicks after Tottenham striker Harry Kane had scored a spectacular own goal.
Liverpool had far too much attacking power for Bournemouth to withstand as they moved back into the top four with a 4-0 win at the Vitality Stadium.
Manchester United held on for a 2-1 win at West Bromwich Albion to cut neighbours Manchester City's lead at the top of the Premier League back to 11 points.
Leaders Manchester City powered to their 16th successive win in the Premier League with a 4-1 thrashing of Tottenham at the Etihad Stadium.
Arsenal returned to winning ways but had Mesut Ozil to thank for scoring a wonderful winner as they toiled against out-of-form Newcastle.
Time was on Chelsea's side as Marcos Alonso's free-kick earned a 1-0 Premier League win over Southampton.
Arsenal lost further ground on the Premier League leaders after they were held to a goalless draw at West Ham.
Tottenham climbed back into the Premier League's top four as Serge Aurier's fluke-goal and a header from Son Heung-min sealed a 2-0 victory over Brighton.
Liverpool manager Jurgen Klopp reunited the "Fab Four" but his prolific attacking quartet were all distinctly off-key as West Brom held out for a goalless draw at Anfield.
Manchester City set a new Premier League record of 15 consecutive wins with a 4-0 victory at bottom club Swansea.
Romelu Lukaku got a much-needed goal as Manchester United moved on from their galling derby defeat by beating Bournemouth.
Willian scored one and made two others as Chelsea finally turned in a display worthy of Premier League champions to win 3-1 at Huddersfield.
Runaway Premier League leaders Manchester City opened up an eye-watering double-digit lead over rivals Manchester United after Nicolas Otamendi fired Pep Guardiola's men to derby victory.
Wayne Rooney's first Merseyside derby goal earned Everton a 1-1 draw at Anfield as Liverpool manager Jurgen Klopp's selection gamble backfired.
Olivier Giroud climbed off the bench to rescue a point for Arsenal in a 1-1 draw at Southampton.
Ayoze Perez's late own goal cost Newcastle a precious Premier League draw as Leicester ruined the Magpies' 125th birthday celebrations.
Tottenham ended a four-match Premier League winless streak in style with Harry Kane scoring a brace as they thrashed Stoke 5-1 at Wembley.
Marko Arnautovic's first West Ham goal secured a 1-0 victory over Chelsea and a first win for manager David Moyes.
Manchester City left it late for the third game in a row as they beat West Ham United 2-1 at the Etihad Stadium thanks to David Silva's strike and extended their Premier League lead.
Bournemouth and Southampton shared the spoils as an entertaining match on the south coast finished in a 1-1 draw.
Jesse Lingard scored twice but Paul Pogba was sent off as Manchester United beat Arsenal 3-1 in a breathless match at the Emirates Stadium.
Talk of Burnley qualifying for Europe was dealt a sobering blow with defeat at improving Leicester.
Gylfi Sigurdsson and Dominic Calvert-Lewin scored second-half goals as Sam Allardyce's first game in charge of Everton ended in a 2-0 home win over Huddersfield.
Davinson Sanchez's red card forced Tottenham to fight for a 1-1 draw at Watford, toughening their battle to climb back into the Premier League's top four.
Philippe Coutinho and Roberto Firmino demolished Brighton to keep Liverpool's top-four charge on track.
A sparkling two-goal performance from Eden Hazard helped Chelsea come from a goal down to beat Newcastle 3-1 at Stamford Bridge and go level on points with second-placed Manchester United.
Substitute Mohamed Salah's purple patch continued with two more goals as Liverpool ground out a controversial 3-0 win at Stoke.
Raheem Sterling scored a dramatic winner as Manchester City maintained their winning run with a last-gasp 2-1 defeat of Southampton.
Antonio Conte was sent off as Chelsea claimed a fifth Premier League win in six games with a 1-0 defeat of Swansea.
Arsenal strengthened their position in the Premier League top four as they made light work of Huddersfield to maintain their healthy home form.
Newcastle ended a run of four straight defeats after coming back from 2-0 down to claim a gutsy point at West Brom.