Javier Hernandez netted an equaliser for West Ham to thwart Chelsea again and dent their bid for Champions League football, while earning his side an important point in their bid to survive relegation in a 1-1 draw on Saturday.
Danny Welbeck scored twice as Arsenal deepened Southampton's relegation worries with a 3-2 win in a game that saw both sides reduced to 10 men in stoppage time at the Emirates Stadium.
Manchester United produced an incredible second-half comeback to beat rivals Manchester City 3-2 and leave them waiting for confirmation of the Premier League title after a thrilling game at the Etihad Stadium.
Christian Eriksen was credited with a brace as Harry Kane was denied a crucial goal in the Golden Boot race in Tottenham's 2-1 win over Stoke at the bet365 Stadium.
Everton and Liverpool had to settle for a share of the spoils as the Merseyside derby ended in a goalless stalemate at Goodison Park.
Dele Alli's double drove Tottenham to a first Stamford Bridge win over Chelsea since 1990 and left the Blues' Champions League qualification bid in tatters.
Arsenal scored three times in the last 15 minutes to condemn Premier League strugglers Stoke to defeat, despite a fairly positive showing from the Potters in north London.
Manchester City are just one win away from securing the Premier League title after a 3-1 victory over Everton at Goodison Park.
Romelu Lukaku's 100th Premier League goal set Manchester United on course for a comfortable victory against relegation-threatened Swansea.
Mohamed Salah's 37th goal of the season in all competitions handed Jurgen Klopp victory in his 100th Premier League match in charge of Liverpool.
Pedro's extra-time header saw Chelsea advance to the FA Cup semifinals at the expense of Leicester City.
Southampton are through to the FA Cup semi-finals for the first time in 15 years after a 2-0 victory over Wigan in Mark Hughes' first game in charge.
Manchester United were unable to match the intensity shown during Jose Mourinho's extraordinary pre-match press conference, but headers from Romelu Lukaku and Nemanja Matic saw them through to the FA Cup semi-finals at Brighton's expense.
Mohamed Salah's record-setting season shows no signs of slowing down as four goals in the 5-0 victory over Watford put him in pole position for the Premier League Golden Boot.
Tottenham Hotspur strolled into the semifinals of the FA Cup with a Christian Eriksen-inspired 3-0 victory over Swansea City.
David Silva struck twice as Manchester City took another stride towards their seemingly inevitable coronation as Premier League champions with a 2-0 victory at Stoke.
Tottenham Hotspur bounced back from their Champions League defeat to Juventus with a 4-1 win at Bournemouth in a game overshadowed by injury to Harry Kane.
Arsenal strolled to a much-needed win as Shkodran Mustafi, Pierre-Emerick Aubameyang and Henrikh Mkhitaryan saw off Watford 3-0 at the Emirates Stadium and Petr Cech kept his 200th Premier League clean sheet.
Two first-half goals gave Chelsea a 2-1 home victory over a Crystal Palace side whose relegation worries increase.
Everton registered a third successive victory at Goodison Park by beating Brighton 2-0.
Two goals from Marcus Rashford gave Manchester United a crucial 2-1 victory over Liverpool at Old Trafford, putting them five points clear of their rivals in second place in the Premier League.
Nemanja Matic struck in stoppage time as Manchester United came from two goals down to secure a vital 3-2 victory at Crystal Palace.
Bernardo Silva scored the only goal as Manchester City took another stride towards the Premier League title with a 1-0 victory over Chelsea.
Arsene Wenger remains under intense pressure as Arsenal were deservedly beaten 2-1 by Brighton & Hove Albion at the Amex Stadium on Sunday.
Tottenham warmed up for their Champions League tie with Juventus by easing to a 2-0 victory over Huddersfield at Wembley.
Mohamed Salah scored for the seventh successive match to continue a remarkable scoring spree that is the best in Europe as Liverpool comfortably beat Newcastle United 2-0.
Manchester City inflicted more pain on Arsene Wenger with a second crushing 3-0 victory over his Arsenal side in the space of four days.
Tottenham overcame Rochdale 6-1 in the FA Cup but video technology reduced the fifth-round replay at Wembley to a farce.
Swansea reached their first FA Cup quarterfinal since 1964 with a 2-0 home victory over Sheffield Wednesday.
Manchester City breezed past woeful Arsenal 3-0 to lift the Carabo Cup, Pep Guardiola's first trophy in English football, at Wembley.
Manchester City midfielder Kevin De Bruyne is facing a spell on the sidelines after injuring his right knee in training on Wednesday.
Manchester City, who romped to Premier League success by 19 points last season, began the defence of their title with a 2-0 win away against Arsenal and new manager Unai Emery on Sunday.
Sadio Mane had two goals for the first time since February 2017 and Mohamed Salah also scored as Liverpool opened their Premier League season with a 4-0 victory over West Ham United at Anfield.
Richarlison scored twice in his first Premier League appearance for 10-man Everton, but a late goal from Raul Jimenez helped Wolverhampton Wanderers salvage a 2-2 draw at the Molineux Stadium.
Chelsea manager Maurizio Sarri made a winning start to life in the Premier League as his team enjoyed a 3-0 win over Huddersfield Town at the John Smith's Stadium on Saturday.
Jan Vertonghen and Dele Alli scored first-half goals as Tottenham Hotspur opened their Premier League season with a 2-1 victory over Newcastle United at St James' Park.
Paul Pogba and Luke Shaw scored as Manchester City beat Leicester City 2-1 to open the 2018-19 Premier League season at Old Trafford on Friday night.
Leicester City striker Jamie Vardy has signalled his intention to see out his career with the Foxes as he signed a new contract until June 2022.
Athletic Bilbao have confirmed that Kepa Arrizabalaga has paid the €80 million buyout clause in his contract as he edges closer to completing a move to Chelsea.
Real Madrid midfielder Mateo Kovacic will join Chelsea on a season-long loan deal as part of the deal that sees goalkeeper Thibaut Courtois move to Real in a permanent deal.
Two goals from Sergio Aguero -- his 200th and 201st for the club -- proved decisive as Manchester City easily saw off FA Cup winners Chelsea 2-0 to win the Community Shield at Wembley.
Liverpool have completed the signing of Alisson on a six-year contract after agreeing with Roma on a world-record transfer for a goalkeeper.
Chelsea have completed the signing of Jorginho, beating Manchester City to the signature of the former Napoli midfielder.
Chelsea completed the long-expected hiring of Maurizio Sarri as their new manager on Saturday, appointing him after parting ways with Antonio Conte.
Chelsea have sacked coach Antonio Conte, paving the way for Maurizio Sarri to take over.
Manchester City have completed the signing of attacking midfielder Riyad Mahrez from Leicester City, the clubs announced on Tuesday.
Liverpool have announced that new signing Naby Keita will be given the No. 8 shirt last worn by former captain Steven Gerrard.
Manchester United have reached an agreement with Shakhtar Donetsk for the transfer of Brazil international midfielder Fred, the Premier League club confirmed on Tuesday.
Stephan Lichtsteiner has become Unai Emery's first signing for Arsenal after joining the Premier League side on a free transfer from Juventus.
Frank Lampard has been appointed the new manager of Derby County on a three-year contract, with former Chelsea academy coach Jody Morris as his assistant.
Liverpool have announced a deal to sign Brazilian midfielder Fabinho from Monaco.
Arsenal have hired former Paris Saint-Germain manager Unai Emery to take them into a new era following Arsene Wenger's departure, with sources telling that he has signed a three-year contract.
Eden Hazard fired Chelsea to FA Cup glory against Manchester United as Antonio Conte's expected farewell ended with a memorable triumph against old foe Jose Mourinho.
Michael Carrick bade farewell to Old Trafford by helping set up the goal that delivered a 1-0 win for Manchester United over Watford.
Champions Manchester City became the first club to amass 100 Premier League points after Gabriel Jesus scored a dramatic stoppage-time winner at Southampton.
Tottenham said goodbye to Wembley in style as they came from behind to beat Leicester 5-4 in a thrilling final-day Premier League encounter.
Ayoze Perez struck twice to end Chelsea's faint hopes of Champions League qualification as Newcastle secured a top-10 finish on their return to the Premier League.
Liverpool secured a top-four spot with very little fuss as Mohamed Salah's new Premier League goalscoring record paved the way for a 4-0 victory over Brighton.
Arsene Wenger bowed out with a victory as Pierre-Emerick Aubameyang's first-half goal secured a 1-0 win for Arsenal in their season finale against Huddersfield.
West Ham and Manchester United played out a dull goalless draw at the London Stadium -- although the result was enough to see Jose Mourinho's side secure second place in the Premier League.