Liverpool were forced to settle for a goalless draw at Southampton on Saturday as they dominated the hosts without being able to find a breakthrough.
Yaya Toure returned from his Manchester City exile to inspire a 2-1 victory at Crystal Palace that maintains their pursuit of the Premier League title.
Fast-starting Watford inflicted Premier League champions Leicester's sixth defeat of the season with a 2-1 win at Vicarage Road.
Arsene Wenger's inability to beat Jose Mourinho in a competitive game continued at Old Trafford on Saturday, though his Arsenal side secured a 1-1 draw against Manchester United thanks to a late equaliser from Olivier Giroud.
Liverpool went top of the Premier League with a convincing 6-1 victory against Watford courtesy of goals from Philippe Coutinho, Emre Can, Roberto Firmino, Georginio Wijnaldum and a brace from Sadio Mane.
A Harry Kane penalty stopped Arsenal going top of the Premier League as Tottenham Hotspur earned a 1-1 draw in the North London derby.
Manchester United and Jose Mourinho returned to winning ways with a 3-1 victory at Swansea.
Matt Phillips ended Leicester's 20-game unbeaten home league run as West Bromwich Albion clinched a 2-1 win at the King Power Stadium.
Eden Hazard scored twice as a dominant Chelsea inflicted a 5-0 thrashing on Everton at Stamford Bridge to move to the top of the Premier League table.
Marten de Roon headed a last-gasp equaliser as Middlesbrough snatched a 1-1 draw against Premier League leaders Manchester City at the Etihad Stadium.
Eden Hazard scored a goal and created another as Chelsea beat Southampton 2-0 at St Mary's to move up to fourth in the Premier League table.
Everton returned to winning ways as goals from Romelu Lukaku and Ross Barkley secured a 2-0 victory over West Ham United at Goodison Park.
Liverpool came out on top in a six-goal thriller at Selhurst Park as they secured a 4-2 victory over Crystal Palace.
Tottenham's revenge mission against Leicester ended in disappointment as Ahmed Musa earned the Premier League champions a 1-1 draw at White Hart Lane.
Alexis Sanchez and Olivier Giroud both hit braces as Arsenal moved to the top of the Premier League table with a 4-1 victory over Sunderland at the Stadium of Light.
Pep Guardiola was able to breathe a sigh of relief after the longest winless run of his managerial career ended with a 4-0 victory against West Brom at The Hawthorns.
Jose Mourinho cut a frustrated figure in the stands as Manchester United failed to turn supremacy into victory, with Tom Heaton's man-of-the-match display helping Burnley sneak a goalless draw at his former club.
Juan Mata gave Manchester United a timely shot in the arm as Jose Mourinho's men extended Manchester City's alarming winless streak to progress to the EFL Cup quarterfinals.
West Ham United's return to form continued as they beat Chelsea 2-0 in the fourth round of the EFL Cup.
Daniel Sturridge struck twice at Anfield to see off Tottenham and send Liverpool into the fifth round of the EFL Cup.
Alex Oxlade-Chamberlain staked a claim for more regular involvement in the Arsenal side as he struck a brace to see off Reading in the fourth round of the EFL Cup.
Jose Mourinho endured a torrid return to Chelsea, watching his Manchester United side concede a goal after 30 seconds as they slumped to a 4-0 defeat.
John Stones was at the centre of the action as Manchester City drew 1-1 with Southampton at the Etihad Stadium on Sunday to go back to the top of the Premier League table.
Liverpool missed the chance to top the Premier League after a dominant display brought them a 2-1 win at home to West Bromwich Albion -- but not the two-goal margin they had needed to reach the summit.
Champions Leicester returned to form in the Premier League as a Christian Fuchs wonder strike capped a 3-1 win over Crystal Palace.
Arsenal wasted a host of chances to toast Arsene Wenger's 67th birthday, labouring to a goalless Premier League draw with struggling Middlesbrough.
Manchester United and Liverpool played to rare goalless draw in their heated rivalry as neither side could find a breakthrough at Anfield on Monday night.
Southampton climbed into the Premier League's top eight with a convincing 3-1 home defeat of Burnley at the start of a period that could define their season.
Bob Bradley's first game as Swansea manager ended in defeat as his side were narrowly beaten by 10-man Arsenal in an entertaining clash at the Emirates Stadium.
Maarten Stekelenburg saved two penalties as Everton held Premier League leaders Manchester City to a 1-1 draw at the Etihad Stadium.
Arsenal have hired former Paris Saint-Germain manager Unai Emery to take them into a new era following Arsene Wenger's departure, with sources telling that he has signed a three-year contract.
Eden Hazard fired Chelsea to FA Cup glory against Manchester United as Antonio Conte's expected farewell ended with a memorable triumph against old foe Jose Mourinho.
Michael Carrick bade farewell to Old Trafford by helping set up the goal that delivered a 1-0 win for Manchester United over Watford.
Champions Manchester City became the first club to amass 100 Premier League points after Gabriel Jesus scored a dramatic stoppage-time winner at Southampton.
Tottenham said goodbye to Wembley in style as they came from behind to beat Leicester 5-4 in a thrilling final-day Premier League encounter.
Ayoze Perez struck twice to end Chelsea's faint hopes of Champions League qualification as Newcastle secured a top-10 finish on their return to the Premier League.
Liverpool secured a top-four spot with very little fuss as Mohamed Salah's new Premier League goalscoring record paved the way for a 4-0 victory over Brighton.
Arsene Wenger bowed out with a victory as Pierre-Emerick Aubameyang's first-half goal secured a 1-0 win for Arsenal in their season finale against Huddersfield.
West Ham and Manchester United played out a dull goalless draw at the London Stadium -- although the result was enough to see Jose Mourinho's side secure second place in the Premier League.
Yaya Toure bade farewell to the Etihad Stadium as champions Manchester City set a hat trick of Premier League records in a routine 3-1 win over Brighton.
Jamie Vardy returned to haunt Arsene Wenger on his farewell tour as Leicester cruised past 10-man Arsenal 3-1.
Tottenham overcame a nervy night at Wembley to book their Champions League place for next season with a 1-0 win over Newcastle.
Huddersfield secured their Premier League status with a valiant 1-1 draw at Stamford Bridge which significantly dented Chelsea's slim top-four hopes.
Southampton took a huge step towards safety as a 1-0 win at Swansea inched their Welsh rivals towards the Premier League trapdoor and relegated West Brom in the process.
Arsenal gave Arsene Wenger a memorable Emirates Stadium send-off as the outgoing boss saw his side thrash Burnley.
Chelsea's Champions League hopes for next season received a boost following Sunday's narrow victory over Liverpool.
Manchester City failed to fire on the day they were presented with the Premier League trophy as Huddersfield Town claimed a vital point at the Etihad Stadium.
Tom Davies scored deep into added time as Everton salvaged a 1-1 draw against 10-man Southampton at Goodison Park, preventing their opponents from escaping the Premier League relegation zone.
West Bromwich Albion kept their slim survival hopes alive after Jake Livemore's dramatic injury time goal earned a 1-0 win against Tottenham Hotspur.
Pascal Gross scored the goal which sank Manchester United 1-0 to guarantee Premier League football for Brighton next season.
Harry Kane did his talking on the pitch as Tottenham reasserted themselves in the race for the Champions League with a 2-0 win over Watford.
Arsene Wenger was denied a point on his last visit to Old Trafford as Arsenal manager when Marouane Fellaini's injury-time header snatched victory for Manchester United.
Manchester City surpassed 100 Premier League goals for the season and left West Ham waiting to confirm top flight football next season with a 4-1 win at the London Stadium.
Chelsea's chase for a top-four Premier League spot gathered pace as Cesc Fabregas scored a landmark goal to deepen Swansea's relegation concerns.
Premier League leading scorer Mohamed Salah had a rare off day as Liverpool continue to stumble towards guaranteeing a top-four finish after a goalless draw at home to Stoke.
Manchester City celebrated their title success in style with a resounding 5-0 win over Swansea at the Etihad Stadium.
Olivier Giroud proved the scourge of Southampton once again, setting Chelsea on course for FA Cup semifinal success and a mouth-watering clash with Manchester United.
A late flurry of goals saw Arsenal secure a 4-1 win over West Ham in their first game since Arsene Wenger revealed he is stepping down as boss.
Ander Herrera has Manchester United dreaming of FA Cup glory after Tottenham Hotspur again suffered semifinal sorrow.
A late strike from Salomon Rondon helped bottom-of-the-table West Bromwich Albion come from behind to draw 2-2 against Liverpool on Saturday at The Hawthorns.