Manchester United and Jose Mourinho returned to winning ways with a 3-1 victory at Swansea.
Matt Phillips ended Leicester's 20-game unbeaten home league run as West Bromwich Albion clinched a 2-1 win at the King Power Stadium.
Eden Hazard scored twice as a dominant Chelsea inflicted a 5-0 thrashing on Everton at Stamford Bridge to move to the top of the Premier League table.
Marten de Roon headed a last-gasp equaliser as Middlesbrough snatched a 1-1 draw against Premier League leaders Manchester City at the Etihad Stadium.
Eden Hazard scored a goal and created another as Chelsea beat Southampton 2-0 at St Mary's to move up to fourth in the Premier League table.
Everton returned to winning ways as goals from Romelu Lukaku and Ross Barkley secured a 2-0 victory over West Ham United at Goodison Park.
Liverpool came out on top in a six-goal thriller at Selhurst Park as they secured a 4-2 victory over Crystal Palace.
Tottenham's revenge mission against Leicester ended in disappointment as Ahmed Musa earned the Premier League champions a 1-1 draw at White Hart Lane.
Alexis Sanchez and Olivier Giroud both hit braces as Arsenal moved to the top of the Premier League table with a 4-1 victory over Sunderland at the Stadium of Light.
Pep Guardiola was able to breathe a sigh of relief after the longest winless run of his managerial career ended with a 4-0 victory against West Brom at The Hawthorns.
Jose Mourinho cut a frustrated figure in the stands as Manchester United failed to turn supremacy into victory, with Tom Heaton's man-of-the-match display helping Burnley sneak a goalless draw at his former club.
Juan Mata gave Manchester United a timely shot in the arm as Jose Mourinho's men extended Manchester City's alarming winless streak to progress to the EFL Cup quarterfinals.
West Ham United's return to form continued as they beat Chelsea 2-0 in the fourth round of the EFL Cup.
Daniel Sturridge struck twice at Anfield to see off Tottenham and send Liverpool into the fifth round of the EFL Cup.
Alex Oxlade-Chamberlain staked a claim for more regular involvement in the Arsenal side as he struck a brace to see off Reading in the fourth round of the EFL Cup.
Jose Mourinho endured a torrid return to Chelsea, watching his Manchester United side concede a goal after 30 seconds as they slumped to a 4-0 defeat.
John Stones was at the centre of the action as Manchester City drew 1-1 with Southampton at the Etihad Stadium on Sunday to go back to the top of the Premier League table.
Liverpool missed the chance to top the Premier League after a dominant display brought them a 2-1 win at home to West Bromwich Albion -- but not the two-goal margin they had needed to reach the summit.
Champions Leicester returned to form in the Premier League as a Christian Fuchs wonder strike capped a 3-1 win over Crystal Palace.
Arsenal wasted a host of chances to toast Arsene Wenger's 67th birthday, labouring to a goalless Premier League draw with struggling Middlesbrough.
Manchester United and Liverpool played to rare goalless draw in their heated rivalry as neither side could find a breakthrough at Anfield on Monday night.
Southampton climbed into the Premier League's top eight with a convincing 3-1 home defeat of Burnley at the start of a period that could define their season.
Bob Bradley's first game as Swansea manager ended in defeat as his side were narrowly beaten by 10-man Arsenal in an entertaining clash at the Emirates Stadium.
Maarten Stekelenburg saved two penalties as Everton held Premier League leaders Manchester City to a 1-1 draw at the Etihad Stadium.
Dele Alli rescued a late point for Tottenham at West Brom as Spurs missed the chance to go top of the Premier League.
Diego Costa, Eden Hazard and Victor Moses were all on target for Chelsea as they brushed aside Leicester City with a 3-0 victory at Stamford Bridge.
Any suggestion that Chelsea might be set to sack head coach Antonio Conte is "utter nonsense," a club source has told.
Chelsea promised Antonio Conte a £60m bid to lure Leonardo Bonucci from Juventus in January, claims The Telegraph.
Laurent Koscielny scored a stoppage-time winner after Burnley had appeared set to share the spoils at Turf Moor on Sunday.
Southampton held Leicester to a battling goalless draw as the Premier League champions continued to stutter.
Liverpool had far too much attacking power for Bournemouth to withstand as they moved back into the top four with a 4-0 win at the Vitality Stadium.
Manchester United held on for a 2-1 win at West Bromwich Albion to cut neighbours Manchester City's lead at the top of the Premier League back to 11 points.
Leaders Manchester City powered to their 16th successive win in the Premier League with a 4-1 thrashing of Tottenham at the Etihad Stadium.
Arsenal returned to winning ways but had Mesut Ozil to thank for scoring a wonderful winner as they toiled against out-of-form Newcastle.
Time was on Chelsea's side as Marcos Alonso's free-kick earned a 1-0 Premier League win over Southampton.
Arsenal lost further ground on the Premier League leaders after they were held to a goalless draw at West Ham.
Tottenham climbed back into the Premier League's top four as Serge Aurier's fluke-goal and a header from Son Heung-min sealed a 2-0 victory over Brighton.
Liverpool manager Jurgen Klopp reunited the "Fab Four" but his prolific attacking quartet were all distinctly off-key as West Brom held out for a goalless draw at Anfield.
Manchester City set a new Premier League record of 15 consecutive wins with a 4-0 victory at bottom club Swansea.
Romelu Lukaku got a much-needed goal as Manchester United moved on from their galling derby defeat by beating Bournemouth.
Willian scored one and made two others as Chelsea finally turned in a display worthy of Premier League champions to win 3-1 at Huddersfield.
Runaway Premier League leaders Manchester City opened up an eye-watering double-digit lead over rivals Manchester United after Nicolas Otamendi fired Pep Guardiola's men to derby victory.
Wayne Rooney's first Merseyside derby goal earned Everton a 1-1 draw at Anfield as Liverpool manager Jurgen Klopp's selection gamble backfired.
Olivier Giroud climbed off the bench to rescue a point for Arsenal in a 1-1 draw at Southampton.
Ayoze Perez's late own goal cost Newcastle a precious Premier League draw as Leicester ruined the Magpies' 125th birthday celebrations.
Tottenham ended a four-match Premier League winless streak in style with Harry Kane scoring a brace as they thrashed Stoke 5-1 at Wembley.
Marko Arnautovic's first West Ham goal secured a 1-0 victory over Chelsea and a first win for manager David Moyes.
Manchester City left it late for the third game in a row as they beat West Ham United 2-1 at the Etihad Stadium thanks to David Silva's strike and extended their Premier League lead.
Bournemouth and Southampton shared the spoils as an entertaining match on the south coast finished in a 1-1 draw.
Jesse Lingard scored twice but Paul Pogba was sent off as Manchester United beat Arsenal 3-1 in a breathless match at the Emirates Stadium.
Talk of Burnley qualifying for Europe was dealt a sobering blow with defeat at improving Leicester.
Gylfi Sigurdsson and Dominic Calvert-Lewin scored second-half goals as Sam Allardyce's first game in charge of Everton ended in a 2-0 home win over Huddersfield.
Davinson Sanchez's red card forced Tottenham to fight for a 1-1 draw at Watford, toughening their battle to climb back into the Premier League's top four.
Philippe Coutinho and Roberto Firmino demolished Brighton to keep Liverpool's top-four charge on track.
A sparkling two-goal performance from Eden Hazard helped Chelsea come from a goal down to beat Newcastle 3-1 at Stamford Bridge and go level on points with second-placed Manchester United.
Substitute Mohamed Salah's purple patch continued with two more goals as Liverpool ground out a controversial 3-0 win at Stoke.
Raheem Sterling scored a dramatic winner as Manchester City maintained their winning run with a last-gasp 2-1 defeat of Southampton.
Antonio Conte was sent off as Chelsea claimed a fifth Premier League win in six games with a 1-0 defeat of Swansea.
Arsenal strengthened their position in the Premier League top four as they made light work of Huddersfield to maintain their healthy home form.
Newcastle ended a run of four straight defeats after coming back from 2-0 down to claim a gutsy point at West Brom.