Gylfi Sigurdsson and Dominic Calvert-Lewin scored second-half goals as Sam Allardyce's first game in charge of Everton ended in a 2-0 home win over Huddersfield.
Davinson Sanchez's red card forced Tottenham to fight for a 1-1 draw at Watford, toughening their battle to climb back into the Premier League's top four.
Philippe Coutinho and Roberto Firmino demolished Brighton to keep Liverpool's top-four charge on track.
A sparkling two-goal performance from Eden Hazard helped Chelsea come from a goal down to beat Newcastle 3-1 at Stamford Bridge and go level on points with second-placed Manchester United.
Substitute Mohamed Salah's purple patch continued with two more goals as Liverpool ground out a controversial 3-0 win at Stoke.
Raheem Sterling scored a dramatic winner as Manchester City maintained their winning run with a last-gasp 2-1 defeat of Southampton.
Antonio Conte was sent off as Chelsea claimed a fifth Premier League win in six games with a 1-0 defeat of Swansea.
Arsenal strengthened their position in the Premier League top four as they made light work of Huddersfield to maintain their healthy home form.
Newcastle ended a run of four straight defeats after coming back from 2-0 down to claim a gutsy point at West Brom.
Ashley Young struck twice against former club Watford as Manchester United won a thrilling contest at Vicarage Road to close to within five points of leaders Manchester City.
Tottenham Hotspur's hopes of returning to the Premier League top four were dashed as they lost 2-1 at Leicester, who rose to ninth in the table thanks to fine finishes from Jamie Vardy and Riyad Mahrez.
Raheem Sterling claimed a lucky late winner as Manchester City came from behind to restore their eight-point Premier League lead with a 2-1 win at Huddersfield.
Alexis Sanchez converted a stoppage-time penalty as Arsenal snatched all three points in a 1-0 win at Burnley.
Mohamed Salah returned to haunt former club Chelsea but Liverpool were denied a hugely significant victory as Willian conjured an equaliser out of nothing at Anfield.
Gary Megson made his case for a longer stay as West Brom manager as his resilient side held Tottenham to a 1-1 draw at Wembley.
Ashley Young's deflected strike proved the slice of luck Manchester United needed to sneak past promoted Brighton.
West Ham secured their first point under David Moyes as Cheikhou Kouyate's header earned a 1-1 draw with Leicester.
David Moyes failed to inspire West Ham as their Premier League woes deepened with defeat in his first match in charge at Watford.
Paul Pogba returned from injury to inspire Manchester United to a 4-1 win over Newcastle at Old Trafford.
Tony Pulis' position at West Brom looks increasingly under threat after Chelsea inflicted the joint-heaviest defeat of his near three-year reign at The Hawthorns.
A virtuoso performance from Mohamed Salah ran Southampton ragged as his two goals inspired Liverpool's 3-0 win at Anfield and fired the Egyptian to the top of the Premier League scoring charts.
Manchester City's record-breaking start to the Premier League season continued with a dominant display against Leicester at the King Power Stadium.
Arsenal proved they are still a force to be reckoned with by blowing away Tottenham in a pulsating north London derby.
A fine header from Alvaro Morata gave Chelsea a 1-0 win over Manchester United at Stamford Bridge as Manchester City stretched their advantage at the top of the Premier League.
Manchester City secured their 10th win in 11 Premier League games, extending their lead at the top of the table with a 3-1 victory over Arsenal at the Etihad Stadium.
Tottenham Hotspur got back to winning ways in domestic football as Son Heung-Min's goal proved enough to see off an unlucky Crystal Palace at Wembley.
Liverpool deepened West Ham United's problems as they strolled to a 4-1 win at the London Stadium.
Peter Crouch's second-half header earned Stoke a point at home to Leicester and ensured a familiar scoreline at the bet365 Stadium.
New boss Claude Puel began his Leicester reign with a routine win over managerless Everton as the Foxes eased away from trouble.
Eden Hazard's first Premier League goal of the season eased Chelsea past Bournemouth 1-0 at Dean Court.
Arsenal have hired former Paris Saint-Germain manager Unai Emery to take them into a new era following Arsene Wenger's departure, with sources telling that he has signed a three-year contract.
Eden Hazard fired Chelsea to FA Cup glory against Manchester United as Antonio Conte's expected farewell ended with a memorable triumph against old foe Jose Mourinho.
Michael Carrick bade farewell to Old Trafford by helping set up the goal that delivered a 1-0 win for Manchester United over Watford.
Champions Manchester City became the first club to amass 100 Premier League points after Gabriel Jesus scored a dramatic stoppage-time winner at Southampton.
Tottenham said goodbye to Wembley in style as they came from behind to beat Leicester 5-4 in a thrilling final-day Premier League encounter.
Ayoze Perez struck twice to end Chelsea's faint hopes of Champions League qualification as Newcastle secured a top-10 finish on their return to the Premier League.
Liverpool secured a top-four spot with very little fuss as Mohamed Salah's new Premier League goalscoring record paved the way for a 4-0 victory over Brighton.
Arsene Wenger bowed out with a victory as Pierre-Emerick Aubameyang's first-half goal secured a 1-0 win for Arsenal in their season finale against Huddersfield.
West Ham and Manchester United played out a dull goalless draw at the London Stadium -- although the result was enough to see Jose Mourinho's side secure second place in the Premier League.
Yaya Toure bade farewell to the Etihad Stadium as champions Manchester City set a hat trick of Premier League records in a routine 3-1 win over Brighton.
Jamie Vardy returned to haunt Arsene Wenger on his farewell tour as Leicester cruised past 10-man Arsenal 3-1.
Tottenham overcame a nervy night at Wembley to book their Champions League place for next season with a 1-0 win over Newcastle.
Huddersfield secured their Premier League status with a valiant 1-1 draw at Stamford Bridge which significantly dented Chelsea's slim top-four hopes.
Southampton took a huge step towards safety as a 1-0 win at Swansea inched their Welsh rivals towards the Premier League trapdoor and relegated West Brom in the process.
Arsenal gave Arsene Wenger a memorable Emirates Stadium send-off as the outgoing boss saw his side thrash Burnley.
Chelsea's Champions League hopes for next season received a boost following Sunday's narrow victory over Liverpool.
Manchester City failed to fire on the day they were presented with the Premier League trophy as Huddersfield Town claimed a vital point at the Etihad Stadium.
Tom Davies scored deep into added time as Everton salvaged a 1-1 draw against 10-man Southampton at Goodison Park, preventing their opponents from escaping the Premier League relegation zone.
West Bromwich Albion kept their slim survival hopes alive after Jake Livemore's dramatic injury time goal earned a 1-0 win against Tottenham Hotspur.
Pascal Gross scored the goal which sank Manchester United 1-0 to guarantee Premier League football for Brighton next season.
Harry Kane did his talking on the pitch as Tottenham reasserted themselves in the race for the Champions League with a 2-0 win over Watford.
Arsene Wenger was denied a point on his last visit to Old Trafford as Arsenal manager when Marouane Fellaini's injury-time header snatched victory for Manchester United.
Manchester City surpassed 100 Premier League goals for the season and left West Ham waiting to confirm top flight football next season with a 4-1 win at the London Stadium.
Chelsea's chase for a top-four Premier League spot gathered pace as Cesc Fabregas scored a landmark goal to deepen Swansea's relegation concerns.
Premier League leading scorer Mohamed Salah had a rare off day as Liverpool continue to stumble towards guaranteeing a top-four finish after a goalless draw at home to Stoke.
Manchester City celebrated their title success in style with a resounding 5-0 win over Swansea at the Etihad Stadium.
Olivier Giroud proved the scourge of Southampton once again, setting Chelsea on course for FA Cup semifinal success and a mouth-watering clash with Manchester United.
A late flurry of goals saw Arsenal secure a 4-1 win over West Ham in their first game since Arsene Wenger revealed he is stepping down as boss.
Ander Herrera has Manchester United dreaming of FA Cup glory after Tottenham Hotspur again suffered semifinal sorrow.
A late strike from Salomon Rondon helped bottom-of-the-table West Bromwich Albion come from behind to draw 2-2 against Liverpool on Saturday at The Hawthorns.