A late strike from Salomon Rondon helped bottom-of-the-table West Bromwich Albion come from behind to draw 2-2 against Liverpool on Saturday at The Hawthorns.
Victor Moses was the match-winner as Chelsea eased the pressure on London rivals Arsenal by denting Burnley's surge for sixth place.
Southampton halted their losing run but a goalless draw at Leicester does little for their Premier League survival hopes.
Manchester United moved to within two points of securing a place in next season's Champions League with a 2-0 win at Bournemouth.
Tottenham's pursuit of Champions League football suffered a minor setback as they squandered a lead to draw 1-1 at Brighton.
Manchester United handed local rivals Manchester City the 2017-18 Premier League title after succumbing to a shock 1-0 defeat against West Bromwich Albion at Old Trafford that keeps the Baggies' slim survival hopes alive.
Arsenal's away woes in the Premier League continued on Sunday when they were beaten 2-1 by Newcastle United at St James' Park.
Mohamed Salah brought his remarkable goal tally to 40 in all competitions this season season by netting once more in a 3-0 win over Bournemouth.
Manchester City responded from a nightmare 10 days in style to put one hand on the Premier League title with a 3-1 win at Tottenham.
Olivier Giroud was the hero for Chelsea as the Blues fought back from two goals down to claim a 3-2 win over Premier League strugglers Southampton at St Mary's.
Javier Hernandez netted an equaliser for West Ham to thwart Chelsea again and dent their bid for Champions League football, while earning his side an important point in their bid to survive relegation in a 1-1 draw on Saturday.
Danny Welbeck scored twice as Arsenal deepened Southampton's relegation worries with a 3-2 win in a game that saw both sides reduced to 10 men in stoppage time at the Emirates Stadium.
Manchester United produced an incredible second-half comeback to beat rivals Manchester City 3-2 and leave them waiting for confirmation of the Premier League title after a thrilling game at the Etihad Stadium.
Christian Eriksen was credited with a brace as Harry Kane was denied a crucial goal in the Golden Boot race in Tottenham's 2-1 win over Stoke at the bet365 Stadium.
Everton and Liverpool had to settle for a share of the spoils as the Merseyside derby ended in a goalless stalemate at Goodison Park.
Dele Alli's double drove Tottenham to a first Stamford Bridge win over Chelsea since 1990 and left the Blues' Champions League qualification bid in tatters.
Arsenal scored three times in the last 15 minutes to condemn Premier League strugglers Stoke to defeat, despite a fairly positive showing from the Potters in north London.
Manchester City are just one win away from securing the Premier League title after a 3-1 victory over Everton at Goodison Park.
Romelu Lukaku's 100th Premier League goal set Manchester United on course for a comfortable victory against relegation-threatened Swansea.
Mohamed Salah's 37th goal of the season in all competitions handed Jurgen Klopp victory in his 100th Premier League match in charge of Liverpool.
Pedro's extra-time header saw Chelsea advance to the FA Cup semifinals at the expense of Leicester City.
Southampton are through to the FA Cup semi-finals for the first time in 15 years after a 2-0 victory over Wigan in Mark Hughes' first game in charge.
Manchester United were unable to match the intensity shown during Jose Mourinho's extraordinary pre-match press conference, but headers from Romelu Lukaku and Nemanja Matic saw them through to the FA Cup semi-finals at Brighton's expense.
Mohamed Salah's record-setting season shows no signs of slowing down as four goals in the 5-0 victory over Watford put him in pole position for the Premier League Golden Boot.
Tottenham Hotspur strolled into the semifinals of the FA Cup with a Christian Eriksen-inspired 3-0 victory over Swansea City.
David Silva struck twice as Manchester City took another stride towards their seemingly inevitable coronation as Premier League champions with a 2-0 victory at Stoke.
Tottenham Hotspur bounced back from their Champions League defeat to Juventus with a 4-1 win at Bournemouth in a game overshadowed by injury to Harry Kane.
Arsenal strolled to a much-needed win as Shkodran Mustafi, Pierre-Emerick Aubameyang and Henrikh Mkhitaryan saw off Watford 3-0 at the Emirates Stadium and Petr Cech kept his 200th Premier League clean sheet.
Two first-half goals gave Chelsea a 2-1 home victory over a Crystal Palace side whose relegation worries increase.
Everton registered a third successive victory at Goodison Park by beating Brighton 2-0.
Manchester City took the derby spoils with a 3-1 victory over rivals Manchester United thanks to goals from David Silva, Sergio Aguero and Ilkay Gundogan, with Anthony Martial pulling one back for the visitors.
Arsenal extended their run without a league win to three games after a 1-1 draw at home to Wolves.
Chelsea's Alvaro Morata had three penalty appeals turned down as Maurizio Sarri's men drew 0-0 against Everton at Stamford Bridge.
Liverpool returned to the top of the Premier League with a controversial 2-0 win over Fulham at Anfield.
Juan Foyth banished the memory of his nightmare Premier League debut to score Tottenham Hotspur's only goal in a 1-0 win at Crystal Palace on Saturday.
Leicester City shared a 0-0 draw with Burnley at the King Power stadium on Saturday when football again took a back seat with emotional tributes to the club's late owner Vichai Srivaddhanaprabha.
Alvaro Morata made it four goals in his last four Premier League matches with a brace as he helped Chelsea to a 3-1 victory over Crystal Palace.
Manchester City made light work of Southampton as three goals inside the opening 18 minutes put them in complete control en route to a 6-1 win.
Tottenham Hotspur held on nervously to beat Wolverhampton Wanderers 3-2 away in the Premier League on Saturday after conceding two second-half penalties.
Arsenal forward Alexandre Lacazette rescued a point nine minutes from time as he cancelled out James Milner's opener in an entertaining 1-1 draw at the Emirates.
Marcus Rashford scored a winner deep into stoppage time as Manchester United snatched a victory against Bournemouth at the Vitality.
Tottenham Hotspur beat West Ham United 3-1 at the London Stadium with Son Heung-Min scoring in each half to book a place in the quarterfinals of the Carabao Cup.
Chelsea reached the League Cup quarterfinals thanks to two own goals in a 3-2 win over second-tier Derby County on Wednesday as Frank Lampard's return to his former club ended in disappointment.
Arsenal held off Blackpool for a 2-1 Carabao Cup win at the Emirates on Wednesday in a match that saw both team's finish with 10 players.
Manchester City returned to the Premier League summit on goal difference with a 1-0 victory over fifth-placed Tottenham Hotspur courtesy of an early goal by Riyad Mahrez at a subdued Wembley Stadium on Monday.
Manchester United bounced back from a disappointing week to beat Everton 2-1 at Old Trafford.
Chelsea went second in the Premier League with an emphatic 4-0 win at Burnley on Sunday which maintained their unbeaten start to the season.
Arsenal's 11-match winning run came to an end with a controversial 2-2 draw at Crystal Palace
Liverpool moved top of the Premier League on Saturday but their "creative mood" almost cost them, manager Juergen Klopp said after lowly Cardiff City briefly threatened a comeback before the Reds ran out 4-1 winners at Anfield.
Mesut Ozil was at his playmaking best as Arsenal stormed back from a goal down to beat Leicester City 3-1 at the Emirates on Monday night.
Two late goals in two minutes from substitutes Dominic Calvert-Lewin and Cenc Tosun saw Everton past Crystal Palace -- for whom Luka Milivojevic had a penalty saved -- 2-0 at Goodison Park.
Liverpool ground out a 1-0 win at Huddersfield as Mohamed Salah's goal took them back up to second place in the Premier League table.
Tottenham Hotspur secured a hard-fought 1-0 win over lowly London rivals West Ham United thanks to a deft first-half finish from Erik Lamela in their Premier League derby on Saturday.
Champions Manchester City took over sole control at the top of the Premier League table with an easy 5-0 win over Burnley, earning them a seventh win from their opening nine games.
Ross Barkley scored an injury-time equaliser as Chelsea salvaged a 2-2 draw with Manchester United on a dramatic afternoon at Stamford Bridge.
Riyad Mahrez smashed a late penalty over the bar as Manchester City and Liverpool played out a dull 0-0 draw at Anfield.
Ross Barkley scored his first goal for Chelsea to help defeat Southampton 3-0 at St. Mary's on Sunday.
Arsenal midfielder Aaron Ramsey scored the goal of the game as Unai Emery's men made it nine consecutive wins in all competitions with this 5-1 victory over Fulham.
A 90th-minute goal by Alexis Sanchez helped Manchester United complete an unlikely comeback and claim a 3-2 win over Newcastle at Old Trafford on Saturday.
Eric Dier scored his first Premier League goal since April 2017 as Tottenham Hotspur defeated Cardiff City 1-0 at Wembley Stadium on Saturday.