Gary Megson made his case for a longer stay as West Brom manager as his resilient side held Tottenham to a 1-1 draw at Wembley.
Ashley Young's deflected strike proved the slice of luck Manchester United needed to sneak past promoted Brighton.
West Ham secured their first point under David Moyes as Cheikhou Kouyate's header earned a 1-1 draw with Leicester.
David Moyes failed to inspire West Ham as their Premier League woes deepened with defeat in his first match in charge at Watford.
Paul Pogba returned from injury to inspire Manchester United to a 4-1 win over Newcastle at Old Trafford.
Tony Pulis' position at West Brom looks increasingly under threat after Chelsea inflicted the joint-heaviest defeat of his near three-year reign at The Hawthorns.
A virtuoso performance from Mohamed Salah ran Southampton ragged as his two goals inspired Liverpool's 3-0 win at Anfield and fired the Egyptian to the top of the Premier League scoring charts.
Manchester City's record-breaking start to the Premier League season continued with a dominant display against Leicester at the King Power Stadium.
Arsenal proved they are still a force to be reckoned with by blowing away Tottenham in a pulsating north London derby.
A fine header from Alvaro Morata gave Chelsea a 1-0 win over Manchester United at Stamford Bridge as Manchester City stretched their advantage at the top of the Premier League.
Manchester City secured their 10th win in 11 Premier League games, extending their lead at the top of the table with a 3-1 victory over Arsenal at the Etihad Stadium.
Tottenham Hotspur got back to winning ways in domestic football as Son Heung-Min's goal proved enough to see off an unlucky Crystal Palace at Wembley.
Liverpool deepened West Ham United's problems as they strolled to a 4-1 win at the London Stadium.
Peter Crouch's second-half header earned Stoke a point at home to Leicester and ensured a familiar scoreline at the bet365 Stadium.
New boss Claude Puel began his Leicester reign with a routine win over managerless Everton as the Foxes eased away from trouble.
Eden Hazard's first Premier League goal of the season eased Chelsea past Bournemouth 1-0 at Dean Court.
Leaders Manchester City strolled past West Brom to maintain their grip at the top of the Premier League.
Liverpool manager Jurgen Klopp got one over on best friend David Wagner as Daniel Sturridge's 100th club goal paved the way for a 3-0 win over Huddersfield at Anfield.
Arsenal came from behind to beat Swansea in Arsene Wenger's 800th Premier League game in charge of the Gunners.
Anthony Martial came off the bench to score the winning goal as Manchester United beat Tottenham 1-0 at Old Trafford.
West Ham eased the pressure on manager Slaven Bilic by fighting back from two goals down to beat Tottenham 3-2 in the Carabao Cup fourth round.
David Unsworth's first match as Everton's caretaker manager ended in a 2-1 defeat at Chelsea in the fourth round of the Carabao Cup.
Claudio Bravo was the hero as stuttering Manchester City needed penalties to see off hard-working Wolves and make the Carabao Cup quarterfinals.
Teenage striker Eddie Nketiah came off the bench to score twice on his home debut and send Arsenal into the quarter-finals of the Carabao Cup at the expense of Norwich.
Manchester United bounced back from their Huddersfield horror show with a comfortable Carabao Cup victory at Swansea.
Harry Kane scored twice as Tottenham Hotspur brushed Liverpool aside 4-1 at Wembley on an afternoon of glaring defensive frailty from Jurgen Klopp's visitors.
The pressure on Everton manager Ronald Koeman increased as his side dropped into the relegation zone after a 5-2 defeat to Arsenal at Goodison Park.
Sergio Aguero equalled Manchester City's goal-scoring record as the Premier League leaders saw off hard-working Burnley 3-0 at the Etihad Stadium.
Huddersfield are celebrating one of their best wins in decades after Aaron Mooy and Laurent Depoitre brought Manchester United's unbeaten Premier League start to a shock halt.
Michy Batshuayi came off the bench to score twice as Chelsea fought back from behind to win a six-goal thriller against Watford.
Manchester City's quadruple trophy bid was sensationally derailed by a shocking 1-0 defeat at third-division Wigan in the FA Cup fifth round on Monday.
Substitute Steve Davies earned Rochdale an FA Cup fifth-round replay at Wembley Stadium with his remarkable stoppage-time equaliser against Tottenham Hotspur at Spotland.
Manchester United overcame the video assistant referee's controversial intervention and reached the FA Cup quarterfinals thanks to Romelu Lukaku's brace at Huddersfield.
Willian dispatched two inch-perfect finishes as Chelsea cruised past Hull 4-0 and into the FA Cup quarter-finals.
Sheffield Wednesday fan Jamie Vardy put the Blades to the sword as Leicester knocked Sheffield United out of the FA Cup.
Chelsea eased the growing pressure on Antonio Conte and returned to the Premier League's top four with a convincing 3-0 win over West Brom.
Liverpool moved back above Tottenham and into third place in the Premier League table as two first-half goals gave them a routine 2-0 victory at struggling Southampton.
Matt Ritchie scored a second-half winner for Newcastle as they lifted themselves out of the relegation places with a 1-0 victory over Manchester United at St James' Park.
Sergio Aguero scored four times as Manchester City extended their Premier League lead to 16 points with a 5-1 demolition of Leicester at the Etihad Stadium.
Everton's Sam Allardyce won the battle of ex-England managers at Goodison Park to ease growing pressure with a 3-1 victory over Roy Hodgson's struggling Crystal Palace.
Harry Kane proved Arsenal's nemesis again as his bullet header earned Tottenham a deserved 1-0 victory in the North London derby.
Erik Lamela scored his first goal in 17 months as Tottenham sauntered past Newport and into the fifth round of the FA Cup.
Swansea recorded their biggest-ever FA Cup win as Notts County were demolished 8-1 at the Liberty Stadium.
Antonio Conte's future as Chelsea boss was cast into further doubt as his 10 men were thrashed 4-1 by Watford on Monday night.
Mohamed Salah and Harry Kane traded stoppage-time goals as Liverpool and Tottenham drew 2-2 in a wild affair at Anfield on Sunday.
Newcastle resisted intense pressure from Crystal Palace to earn a 1-1 draw at Selhurst Park that again took them clear of the bottom three.
`Aaron Ramsey hit a hat trick with Arsenal fans treated to their first showing of their January transfers in tandem as both Henrikh Mkhitaryan and Pierre-Emerick Aubameyang shone in a comfortable 5-1 win over Everton.
Alexis Sanchez's first goal for Manchester United wrapped up a 2-0 victory against Huddersfield on a day when the clubs came together to remember those who lost their lives in the Munich air disaster.
Swansea's resurgence continued as they climbed out of the Premier League relegation zone with a 1-1 draw at Leicester, who were again without want-away midfielder Riyad Mahrez.
Johann Berg Gudmundsson struck a late equaliser as Burnley grabbed a 1-1 draw against Premier League leaders Manchester City at Turf Moor.
Christian Eriksen scored within 11 seconds as Tottenham brushed aside a below-par Manchester United to seal a crunch 2-0 victory in the race for the top four.
Kevin De Bruyne was again the inspiration as Manchester City opened up a 15-point lead at the top of the Premier League with a 3-0 win over West Brom.
Theo Walcott's maiden Everton goals secured a first win in eight matches as a 2-1 triumph over Leicester arrested their slide under Sam Allardyce.
Bournemouth scored three goals in 16 remarkable second-half minutes to record a sensational 3-0 victory against Chelsea at Stamford Bridge on Wednesday evening.
Arsenal have completed the signing of striker Pierre-Emerick Aubameyang from Borussia Dortmund for a fee of €63.75 million (£56m).
Chelsea have completed the signing of Olivier Giroud from Arsenal for a reported £16.25 million on an 18-month contract.
Tottenham Hotspur have completed the signing of winger Lucas Moura from Paris Saint-Germain for a fee of в‚¬28 million.
Liverpool bounced back to winning ways in the Premier League and maintained their Champions League challenge with a 3-0 win at Huddersfield.
Swansea climbed out of the relegation zone for the first time in three months as Petr Cech's dreadful howler helped condemn Arsenal to a 3-1 defeat at the Liberty Stadium.
Two first-half goals were enough to see Manchester City comfortably through to the FA Cup fifth round at Championship side Cardiff City.