Goalkeeper Adrian was the unlikely match-winner for West Ham as the Spaniard scored the deciding penalty after the Hammers and 10-man Everton had battled tooth and nail for a place in the FA Cup fourth round.
Ronald Koeman gained revenge on his old adversary Louis van Gaal as Southampton recorded their first win at Manchester United for 27 years.
Alexis Sanchez scored another breathtaking goal as Arsenal closed back up on the top four of the Premier League with a 3-0 win over Stoke at the Emirates Stadium, where goalkeeper Wojciech Szczesny had been left on the bench.
Alan Pardew enjoyed a fairytale return to Selhurst Park, overseeing a spirited comeback against Tottenham as Crystal Palace secured a first Premier League win since November.
Manchester City lost ground in the Premier League title race after dropping two points against a dogged Everton at Goodison Park.
Jose Mourinho may have again landed himself in hot water by voicing his opinions but he left it to his Chelsea players to do the talking on the pitch against Newcastle as they moved clear at the top of the table.
Lazar Markovic struck his first league goal for Liverpool as Brendan Rodgers' men made hard work of seeing off 10-man Sunderland at the Stadium of Light.
Romelu Lukaku’s injury-time equaliser earned Everton an FA Cup replay at West Ham after a 1-1 draw, ending a miserable run of four consecutive defeats for the Toffees.
Steven Gerrard's long goodbye began by saving Liverpool's blushes as AFC Wimbledon threatened an upset akin to the 1988 FA Cup final.
Birthday boy James Milner struck twice as Manchester City came from behind to scrape past battling Sheffield Wednesday 2-1 in the FA Cup third round.
FA Cup holders Arsenal secured their place in the fourth round with a 2-0 win at the Emirates Stadium over last season's beaten finalists Hull.
A stunning finish from Ander Herrera helped Manchester United edge past a resolute Yeovil and into the FA Cup fourth round.
Chelsea powered into the fourth round of the FA Cup as second-half goals from Willian, Loic Remy and Kurt Zouma completed a 3-0 victory over Watford.
Liverpool have confirmed that Steven Gerrard is to leave the club when his contract expires at the end of the season.
Tottenham enjoyed an unforgettable start to 2015 as Chelsea were disposed of in remarkable fashion, with Jose Mourinho's side shipping five goals as the Premier League title race burst wide open.
Frank Lampard showed why Manchester City were so keen to keep him by scoring a dramatic winner as the champions beat Sunderland 3-2.
Wojciech Szczesny's two goalkeeping howlers gifted Southampton a 2-0 victory over Arsenal that left Arsene Wenger fuming at St Mary's.
Liverpool squandered a somewhat fortuitous lead as a battling Leicester stunned their hosts with two goals in as many second-half minutes to draw 2-2.
Manchester United's faint Premier League title hopes receded even further as they began 2015 with a disappointing 1-1 draw at Stoke.
Papiss Cisse's fifth goal in six games launched a Newcastle fightback as they ended a four-match losing streak with a 3-2 victory over Everton.
Arsenal battled to a 2-1 win at West Ham to close in on the top four in the Premier League.
Ashley Barnes struck a stunning equaliser as Burnley staged a remarkable comeback to snatch a 2-2 draw against champions Manchester City.
A magical performance from Eden Hazard was not enough to inspire Chelsea to victory as Southampton held firm to secure a hard-earned point.
Hugo Lloris refused to be beaten as Manchester United finished an ignominious 2014 with a goalless draw at Tottenham Hotspur.
Arsenal survived the sending-off of striker Olivier Giroud for a reckless head-butt to beat QPR 2-1 at the Emirates Stadium and close back up on the top four of the Premier League.
Wayne Rooney scored twice and set up another goal as Manchester United swatted Newcastle aside with an easy 3-1 win at Old Trafford.
Diego Costa was on target in a 2-0 win as Premier League leaders Chelsea proved a barrier too far for West Ham.
Champions Manchester City again made light of the absence of strikers as they cruised to a 3-1 win at West Brom.
Raheem Sterling provided a single moment of magic to give Liverpool a hard-fought 1-0 victory over Burnley at Turf Moor.
Christian Eriksen was Tottenham's saviour as they survived a storm to edge past Leicester 2-1.
Manchester United have reached an agreement with Shakhtar Donetsk for the transfer of Brazil international midfielder Fred, the Premier League club confirmed on Tuesday.
Stephan Lichtsteiner has become Unai Emery's first signing for Arsenal after joining the Premier League side on a free transfer from Juventus.
Frank Lampard has been appointed the new manager of Derby County on a three-year contract, with former Chelsea academy coach Jody Morris as his assistant.
Liverpool have announced a deal to sign Brazilian midfielder Fabinho from Monaco.
Arsenal have hired former Paris Saint-Germain manager Unai Emery to take them into a new era following Arsene Wenger's departure, with sources telling that he has signed a three-year contract.
Eden Hazard fired Chelsea to FA Cup glory against Manchester United as Antonio Conte's expected farewell ended with a memorable triumph against old foe Jose Mourinho.
Michael Carrick bade farewell to Old Trafford by helping set up the goal that delivered a 1-0 win for Manchester United over Watford.
Champions Manchester City became the first club to amass 100 Premier League points after Gabriel Jesus scored a dramatic stoppage-time winner at Southampton.
Tottenham said goodbye to Wembley in style as they came from behind to beat Leicester 5-4 in a thrilling final-day Premier League encounter.
Ayoze Perez struck twice to end Chelsea's faint hopes of Champions League qualification as Newcastle secured a top-10 finish on their return to the Premier League.
Liverpool secured a top-four spot with very little fuss as Mohamed Salah's new Premier League goalscoring record paved the way for a 4-0 victory over Brighton.
Arsene Wenger bowed out with a victory as Pierre-Emerick Aubameyang's first-half goal secured a 1-0 win for Arsenal in their season finale against Huddersfield.
West Ham and Manchester United played out a dull goalless draw at the London Stadium -- although the result was enough to see Jose Mourinho's side secure second place in the Premier League.
Yaya Toure bade farewell to the Etihad Stadium as champions Manchester City set a hat trick of Premier League records in a routine 3-1 win over Brighton.
Jamie Vardy returned to haunt Arsene Wenger on his farewell tour as Leicester cruised past 10-man Arsenal 3-1.
Tottenham overcame a nervy night at Wembley to book their Champions League place for next season with a 1-0 win over Newcastle.
Huddersfield secured their Premier League status with a valiant 1-1 draw at Stamford Bridge which significantly dented Chelsea's slim top-four hopes.
Southampton took a huge step towards safety as a 1-0 win at Swansea inched their Welsh rivals towards the Premier League trapdoor and relegated West Brom in the process.
Arsenal gave Arsene Wenger a memorable Emirates Stadium send-off as the outgoing boss saw his side thrash Burnley.
Chelsea's Champions League hopes for next season received a boost following Sunday's narrow victory over Liverpool.
Manchester City failed to fire on the day they were presented with the Premier League trophy as Huddersfield Town claimed a vital point at the Etihad Stadium.
Tom Davies scored deep into added time as Everton salvaged a 1-1 draw against 10-man Southampton at Goodison Park, preventing their opponents from escaping the Premier League relegation zone.
West Bromwich Albion kept their slim survival hopes alive after Jake Livemore's dramatic injury time goal earned a 1-0 win against Tottenham Hotspur.
Pascal Gross scored the goal which sank Manchester United 1-0 to guarantee Premier League football for Brighton next season.
Harry Kane did his talking on the pitch as Tottenham reasserted themselves in the race for the Champions League with a 2-0 win over Watford.
Arsene Wenger was denied a point on his last visit to Old Trafford as Arsenal manager when Marouane Fellaini's injury-time header snatched victory for Manchester United.
Manchester City surpassed 100 Premier League goals for the season and left West Ham waiting to confirm top flight football next season with a 4-1 win at the London Stadium.
Chelsea's chase for a top-four Premier League spot gathered pace as Cesc Fabregas scored a landmark goal to deepen Swansea's relegation concerns.
Premier League leading scorer Mohamed Salah had a rare off day as Liverpool continue to stumble towards guaranteeing a top-four finish after a goalless draw at home to Stoke.
Manchester City celebrated their title success in style with a resounding 5-0 win over Swansea at the Etihad Stadium.