Liverpool may want to boost the contract extension offered to Steven Gerrard after the captain bailed them out in a 3-1 comeback victory at Leicester.
Juan Mata and Marcos Rojo both claimed the winner as Manchester United survived a nerve-jangling finish to beat Stoke 2-1 at Old Trafford.
Yaya Toure and Frank Lampard's strikes took Manchester City up to second in the Premier League table and handed Southampton an ominous start to a daunting run of festive fixtures coming up.
Roberto Soldado's barren run came to a timely end as Tottenham rallied to secure a much-needed 2-1 comeback win against Everton.
Willian and Santiago Vergini both hit the woodwork as Sunderland extended their run of good results against Chelsea with a 0-0 draw.
Glen Johnson ensured Steven Gerrard's demotion to the substitutes' bench became a secondary talking point as the full-back proved the unlikely match-winner as Liverpool stumbled to a 1-0 Premier League win.
Manchester United looked more like their old selves as they cruised to a convincing 3-0 win over lacklustre Hull at Old Trafford.
Danny Welbeck bagged a crucial winner for Arsenal as the Gunners clinched a comfortable 1-0 win at West Brom.
Christian Eriksen conjured a last-minute winner for Tottenham Hotspur as Hull City paid in full for Gaston Ramirez's reckless red card.
Liverpool's season went from bad to worse as they let an early lead slip to lose 3-1 at struggling Crystal Palace on Sunday afternoon.
Manchester United moved back into the top four of the Premier League with a 2-1 smash-and-grab raid at Arsenal.
Yaya Toure responded to Manuel Pellegrini's rallying call as he fired champions Manchester City to a 2-1 Premier League win over Swansea.
Chelsea's title charge shows no signs of abating, with West Brom the latest side swatted away by Jose Mourinho's men as the Blues won 2-0.
Swansea stunned Arsenal with two late goals to run out 2-1 winners at the Liberty Stadium and inflict the Gunners' second Premier League defeat of the season.
Tottenham's woes at White Hart Lane took another turn for the worse as Mauricio Pochettino's side slumped to a 2-1 defeat at home to Stoke in the Premier League.
Sergio Aguero saved Manchester City further embarrassment with a double in Saturday's 2-2 Premier League draw at QPR.
Juan Mata stepped off the bench to score the winner as Manchester United returned to winning ways despite a lacklustre display against Crystal Palace.
Diego Costa's 10th goal of the season maintained Premier League leaders Chelsea's unbeaten record and inflicted yet more pain on Liverpool at Anfield.
Harry Kane hit a late winner as Tottenham clinched a 2-1 victory in a bad-tempered clash with 10-man Aston Villa.
Sergio Aguero scored the only goal of the game as Manchester City beat United in the derby.
An Oscar special and an Eden Hazard penalty earned Premier League leaders Chelsea a 2-1 win in a hard-fought west London derby with QPR at Stamford Bridge.
Alexis Sanchez scored twice as Arsenal moved back into the top four of the Barclays Premier League with a 3-0 victory over stubborn Burnley at the Emirates Stadium.
Ayoze Perez was Newcastle's match-winner for the second time in a week as they edged past Liverpool to claim a fourth successive victory.
Rolando Aarons and substitute Moussa Sissoko struck as Newcastle dumped holders Manchester City out of the Capital One Cup with a 2-0 win at the Etihad Stadium.
Dejan Lovren scored a dramatic 95th-minute winner as Liverpool came from behind late on to beat 10-man Swansea 2-1 at Anfield and advance to the Capital One Cup quarter-finals.
Jermaine Grandison's own goal broke Shrewsbury's hearts after Chelsea survived a scare to snatch a late 2-1 win.
Manchester United striker Robin van Persie scored a 94th minute equaliser to deny Jose Mourinho victory over his old boss Louis van Gaal at Old Trafford.
Alexis Sanchez made the most of howlers from Wes Brown and Vito Mannone as Arsenal claimed a 2-0 victory at Sunderland.
Mario Balotelli and Liverpool fired blanks as Hull held on for a goalless Premier League draw at Anfield.
Diafra Sakho's sixth goal in as many Premier League starts gave West Ham a 2-1 victory over champions Manchester City at Upton Park.
Manchester United were unable to match the intensity shown during Jose Mourinho's extraordinary pre-match press conference, but headers from Romelu Lukaku and Nemanja Matic saw them through to the FA Cup semi-finals at Brighton's expense.
Mohamed Salah's record-setting season shows no signs of slowing down as four goals in the 5-0 victory over Watford put him in pole position for the Premier League Golden Boot.
Tottenham Hotspur strolled into the semifinals of the FA Cup with a Christian Eriksen-inspired 3-0 victory over Swansea City.
David Silva struck twice as Manchester City took another stride towards their seemingly inevitable coronation as Premier League champions with a 2-0 victory at Stoke.
Tottenham Hotspur bounced back from their Champions League defeat to Juventus with a 4-1 win at Bournemouth in a game overshadowed by injury to Harry Kane.
Arsenal strolled to a much-needed win as Shkodran Mustafi, Pierre-Emerick Aubameyang and Henrikh Mkhitaryan saw off Watford 3-0 at the Emirates Stadium and Petr Cech kept his 200th Premier League clean sheet.
Two first-half goals gave Chelsea a 2-1 home victory over a Crystal Palace side whose relegation worries increase.
Everton registered a third successive victory at Goodison Park by beating Brighton 2-0.
Two goals from Marcus Rashford gave Manchester United a crucial 2-1 victory over Liverpool at Old Trafford, putting them five points clear of their rivals in second place in the Premier League.
Nemanja Matic struck in stoppage time as Manchester United came from two goals down to secure a vital 3-2 victory at Crystal Palace.
Bernardo Silva scored the only goal as Manchester City took another stride towards the Premier League title with a 1-0 victory over Chelsea.
Arsene Wenger remains under intense pressure as Arsenal were deservedly beaten 2-1 by Brighton & Hove Albion at the Amex Stadium on Sunday.
Tottenham warmed up for their Champions League tie with Juventus by easing to a 2-0 victory over Huddersfield at Wembley.
Mohamed Salah scored for the seventh successive match to continue a remarkable scoring spree that is the best in Europe as Liverpool comfortably beat Newcastle United 2-0.
Manchester City inflicted more pain on Arsene Wenger with a second crushing 3-0 victory over his Arsenal side in the space of four days.
Tottenham overcame Rochdale 6-1 in the FA Cup but video technology reduced the fifth-round replay at Wembley to a farce.
Swansea reached their first FA Cup quarterfinal since 1964 with a 2-0 home victory over Sheffield Wednesday.
Manchester City breezed past woeful Arsenal 3-0 to lift the Carabo Cup, Pep Guardiola's first trophy in English football, at Wembley.
Tottenham Hotspur grabbed an 89th-minute winner against Crystal Palace to move into fourth place after a determined home side had seemed set for a battling draw at Selhurst Park.
Substitute Jesse Lingard headed the winner as Manchester United came from a goal down to beat Chelsea 2-1 at Old Trafford and move back into second place in the Premier League.
Watford moved up to 10th in the table as Troy Deeney's late goal gave them a valuable 1-0 victory over Everton at Vicarage Road.
Liverpool took their goal tally for the season to 103 as they claimed second place in the Premier League with a comfortable 4-1 win over West Ham.
Stoke remain in the relegation zone after an error from goalkeeper Jack Butland meant they had to settle for a 1-1 draw at Leicester.
Manchester City's quadruple trophy bid was sensationally derailed by a shocking 1-0 defeat at third-division Wigan in the FA Cup fifth round on Monday.
Substitute Steve Davies earned Rochdale an FA Cup fifth-round replay at Wembley Stadium with his remarkable stoppage-time equaliser against Tottenham Hotspur at Spotland.
Manchester United overcame the video assistant referee's controversial intervention and reached the FA Cup quarterfinals thanks to Romelu Lukaku's brace at Huddersfield.
Willian dispatched two inch-perfect finishes as Chelsea cruised past Hull 4-0 and into the FA Cup quarter-finals.
Sheffield Wednesday fan Jamie Vardy put the Blades to the sword as Leicester knocked Sheffield United out of the FA Cup.
Chelsea eased the growing pressure on Antonio Conte and returned to the Premier League's top four with a convincing 3-0 win over West Brom.
Liverpool moved back above Tottenham and into third place in the Premier League table as two first-half goals gave them a routine 2-0 victory at struggling Southampton.