QPR's hopes of beating the drop received a major blow as Harry Kane underlined his England credentials with a match-winning brace for Tottenham.
Fabian Delph's first goal in a year helped fire Aston Villa to Wembley as they beat West Brom 2-0 to reach the FA Cup semifinals.
Olivier Giroud and Alexis Sanchez guided Arsenal to a routine 2-1 Premier League victory at struggling QPR, despite Charlie Austin striking back late on.
Chelsea followed up their Capital One Cup victory with a hard-fought 1-0 win on their return to Premier League business at West Ham.
Ashley Young fired Manchester United to a last-minute victory at Newcastle to maintain their charge for a top-four finish.
Tottenham got their top-four tilt back on track by overcoming Swansea 3-2 on a night when Bafetimbi Gomis' collapse had those inside White Hart Lane fearing the worst.
Stand-in captain Jordan Henderson led from the front with his second goal in successive matches as Liverpool maintained their pursuit of a top-four place.
David Silva and James Milner struck late in each half as under-fire reigning champions Manchester City grabbed a scrappy but much-needed 2-0 win over Leicester in the Premier League.
Jose Mourinho claimed the 21st trophy of his career as Chelsea overcame Tottenham with a clinical 2-0 victory in the Capital One Cup final at Wembley.
Arsenal recovered from their midweek European nightmare to beat Everton 2-0 at Emirates Stadium and move back to third in the Premier League.
Liverpool put a huge dent in Manchester City's title hopes with a 2-1 victory which dramatically enhanced their own hopes of a top-four finish.
Wayne Rooney scored his first league goals in over two months to give Manchester United a 2-0 victory over 10-man Sunderland.
Liverpool’s Jordan Henderson was delighted with what he believed was an amazing performance made by his side at St Mary’s Stadium after the Reds took out Southampton 2-0 in the Premier League.
Philippe Coutinho's exceptional strike amid a series of controversial decisions from referee Kevin Friend helped Liverpool overcome Southampton 2-0.
Manchester City warmed up for Tuesday's visit of Barcelona in style by crushing Newcastle 5-0 on a perfect day for the Premier League champions.
Arsenal moved up to third in the Premier League with a hard-fought 2-1 win at Crystal Palace.
Chelsea's troubled week ended in further controversy when Nemanja Matic was sent off as Burnley plundered a late 1-1 Premier League draw at Stamford Bridge.
Swansea completed their first-ever league double over Manchester United to dent the Red Devils' hopes of finishing in the Champions League places.
Wayne Rooney ended his goal drought as Manchester United came from behind to beat Preston and set up a mouth-watering FA Cup quarter-final against Arsenal.
Olivier Giroud struck twice as FA Cup holders Arsenal beat Middlesbrough 2-0 at the Emirates Stadium to book their place in the quarterfinals.
Liverpool exorcised some demons at Selhurst Park by reaching the FA Cup quarterfinals with an impressive win against Crystal Palace.
Willian struck an 89th-minute winner as Chelsea beat Everton 1-0 but the Premier League leaders could face disciplinary action once more after Branislav Ivanovic appeared to headbutt James McCarthy.
Sergio Aguero and Manchester City rediscovered their touch as the champions turned on the style in the second half to win 4-1 at Stoke.
Manchester United cut out the long-ball tactics but they still had to battle their way to a 3-1 win over Burnley at Old Trafford.
Liverpool's Mario Balotelli picked the perfect time to score his first Premier League goal for the club as he stole the headlines from the battle between England strikers present and, potentially, future.
Arsenal moved back into the Premier League top four as they edged out bottom club Leicester 2-1 at the Emirates Stadium.
West Ham were denied a first Premier League win over Manchester United in seven years and 13 attempts by Daley Blind's stoppage-time strike.
Even the occasion of his final Premier League Merseyside derby could not inspire Liverpool captain Steven Gerrard to more heroics as the 224th meeting of the clubs disappointingly finished goalless.
Branislav Ivanovic's rocket gave Chelsea a crucial 2-1 win at Aston Villa - despite the hosts ending their 11-hour goal drought.
Substitute James Milner struck a superb injury-time free-kick as lacklustre champions Manchester City rescued a point with a 1-1 draw against Hull.
Michael Carrick bade farewell to Old Trafford by helping set up the goal that delivered a 1-0 win for Manchester United over Watford.
Champions Manchester City became the first club to amass 100 Premier League points after Gabriel Jesus scored a dramatic stoppage-time winner at Southampton.
Tottenham said goodbye to Wembley in style as they came from behind to beat Leicester 5-4 in a thrilling final-day Premier League encounter.
Ayoze Perez struck twice to end Chelsea's faint hopes of Champions League qualification as Newcastle secured a top-10 finish on their return to the Premier League.
Liverpool secured a top-four spot with very little fuss as Mohamed Salah's new Premier League goalscoring record paved the way for a 4-0 victory over Brighton.
Arsene Wenger bowed out with a victory as Pierre-Emerick Aubameyang's first-half goal secured a 1-0 win for Arsenal in their season finale against Huddersfield.
West Ham and Manchester United played out a dull goalless draw at the London Stadium -- although the result was enough to see Jose Mourinho's side secure second place in the Premier League.
Yaya Toure bade farewell to the Etihad Stadium as champions Manchester City set a hat trick of Premier League records in a routine 3-1 win over Brighton.
Jamie Vardy returned to haunt Arsene Wenger on his farewell tour as Leicester cruised past 10-man Arsenal 3-1.
Tottenham overcame a nervy night at Wembley to book their Champions League place for next season with a 1-0 win over Newcastle.
Huddersfield secured their Premier League status with a valiant 1-1 draw at Stamford Bridge which significantly dented Chelsea's slim top-four hopes.
Southampton took a huge step towards safety as a 1-0 win at Swansea inched their Welsh rivals towards the Premier League trapdoor and relegated West Brom in the process.
Arsenal gave Arsene Wenger a memorable Emirates Stadium send-off as the outgoing boss saw his side thrash Burnley.
Chelsea's Champions League hopes for next season received a boost following Sunday's narrow victory over Liverpool.
Manchester City failed to fire on the day they were presented with the Premier League trophy as Huddersfield Town claimed a vital point at the Etihad Stadium.
Tom Davies scored deep into added time as Everton salvaged a 1-1 draw against 10-man Southampton at Goodison Park, preventing their opponents from escaping the Premier League relegation zone.
West Bromwich Albion kept their slim survival hopes alive after Jake Livemore's dramatic injury time goal earned a 1-0 win against Tottenham Hotspur.
Pascal Gross scored the goal which sank Manchester United 1-0 to guarantee Premier League football for Brighton next season.
Harry Kane did his talking on the pitch as Tottenham reasserted themselves in the race for the Champions League with a 2-0 win over Watford.
Arsene Wenger was denied a point on his last visit to Old Trafford as Arsenal manager when Marouane Fellaini's injury-time header snatched victory for Manchester United.
Manchester City surpassed 100 Premier League goals for the season and left West Ham waiting to confirm top flight football next season with a 4-1 win at the London Stadium.
Chelsea's chase for a top-four Premier League spot gathered pace as Cesc Fabregas scored a landmark goal to deepen Swansea's relegation concerns.
Premier League leading scorer Mohamed Salah had a rare off day as Liverpool continue to stumble towards guaranteeing a top-four finish after a goalless draw at home to Stoke.
Manchester City celebrated their title success in style with a resounding 5-0 win over Swansea at the Etihad Stadium.
Olivier Giroud proved the scourge of Southampton once again, setting Chelsea on course for FA Cup semifinal success and a mouth-watering clash with Manchester United.
A late flurry of goals saw Arsenal secure a 4-1 win over West Ham in their first game since Arsene Wenger revealed he is stepping down as boss.
Ander Herrera has Manchester United dreaming of FA Cup glory after Tottenham Hotspur again suffered semifinal sorrow.
A late strike from Salomon Rondon helped bottom-of-the-table West Bromwich Albion come from behind to draw 2-2 against Liverpool on Saturday at The Hawthorns.
Victor Moses was the match-winner as Chelsea eased the pressure on London rivals Arsenal by denting Burnley's surge for sixth place.
Southampton halted their losing run but a goalless draw at Leicester does little for their Premier League survival hopes.