Substitute Gianluca Lapadula grabbed his maiden AC Milan goal to earn the Rossoneri all three points from their trip to Palermo.
Lazio salvaged a point at Napoli after goals from Keita and Marek Hamsik cancelled each other out in a frenetic two-minute spell at Stadio San Paolo.
Andrea Belotti scored twice as Torino blew Cagliari away 5-1 to reassert their European ambitions.
Inter Milan have confirmed they have parted company with head coach Frank De Boer, less than three months after appointing the former Ajax boss.
The pressure ramped up another notch on Inter Milan manager Frank de Boer after Sampdoria inflicted a fourth defeat in five Serie A games.
Roma blew their chance to keep the pressure on Serie A leaders Juventus as they were held to a goalless draw at struggling Empoli on Sunday.
Giacomo Bonaventura's second-half strike proved enough as AC Milan bounced back from the midweek defeat at Genoa with a 1-0 victory over Pescara at San Siro to move up to third in Serie A.
Gonzalo Higuain's second-half winner saw Juventus clinch their 22nd consecutive home win in Serie A with a 2-1 victory over Napoli.
Mauro Icardi took a major step towards regaining the adoration of hardcore Inter Milan fans while also throwing boss Frank de Boer a lifeline as his brace helped beat Torino 2-1 at San Siro.
Edin Dzeko continued his hot streak in front of goal as Roma battled back from a goal down to win 3-1 at Sassuolo.
Juventus warmed up for their top-of-the-table clash with Napoli by beating Sampdoria 4-1 in Turin.
AC Milan missed the chance to go top of Serie A as they were beaten 3-0 at Genoa.
Roma reinforced their Serie A title credentials with a confident 4-1 home victory over Palermo.
Nikola Kalinic grabbed a hat-trick as Fiorentina came from behind to thump Cagliari 5-3.
Frank de Boer's future as Inter Milan head coach is under serious threat after the Nerazzurri went down 2-1 to Atalanta in Bergamo.
Teenager Manuel Locatelli fired AC Milan to a hard-earned 1-0 win over Serie A leaders Juventus at the San Siro as Vincenzo Montella's young side continued their impressive start to the season.
Two goals from Adem Ljajic helped Torino come from behind to pick up their third win on the bounce with a 4-1 Serie A victory over Palermo.
AC Milan extended their unbeaten run against Chievo to 20 matches and climbed up to third in Serie A with a 3-1 win on the road.
Samir Handanovic's late own goal secured Cagliari a third straight Serie A win and sent Inter Milan spiralling to a third successive defeat in all competitions.
Paulo Dybala's set-piece double saw Serie A leaders Juventus come from behind to defeat Udinese 2-1 at home and extend their lead at the top of the table to five points.
A counter-attacking masterclass saw Roma earn a 3-1 victory against Napoli in their Serie A clash at Stadio San Paolo.
Kostas Manolas had the final word in Roma's scintillating 2-1 victory over Inter Milan.
Gabriel Paletta's first ever AC Milan goal settled a 4-3 thriller against Sassuolo at San Siro.
Iago Falque scored one goal and set up another as Torino reached eighth place with a 2-1 Serie A victory over Fiorentina at the Stadio Olimpico.
Andrea Petagna ended Napoli's unbeaten start to the Serie A season by firing Atalanta to a 1-0 win.
Juventus ensured they would end the weekend in first place in Serie A with a convincing 3-0 victory at Empoli.
Ciro Immobile scored twice as Lazio won 3-0 at Udinese to move third in Serie A.
Josip Ilicic missed a first-half penalty as Fiorentina were held to a goalless draw by AC Milan, who were indebted to goalkeeper Gianluigi Donnarumma at the Artemio Franchi Stadium.
Inter Milan had to be content with a point against Bologna after a fine volley from Ivan Perisic saw them recover to draw 1-1 at Stadio Giuseppe Meazza.
Iago Falque's brace handed Joe Hart's Torino a home victory over Roma for the first time since 1990 as Sinisa Mihajlovic's side prevailed 3-1 in Serie A.
Argentina forward Gonzalo Higuain scored his first goal for AC Milan to earn them a 1-1 draw at Cagliari.
Cristiano Ronaldo scored his first goals for Juventus as they beat Sassuolo 2-1 to continue their perfect start to the Serie A season.
Napoli exorcised some of the ghosts of last season by beating Fiorentina 1-0 in Serie A action on Saturday.
Just three years after going bankrupt, Parma returned to winning ways in Serie A with a surprise 1-0 win over Inter Milan at San Siro.
Serie A title hopefuls Napoli were thumped 3-0 at Sampdoria on Sunday after coach Carlo Ancelotti tinkered with the team, dropping captain Marek Hamsik and forward Jose Callejon.
Cristiano Ronaldo was left waiting for his first Juventus goal after drawing another blank as the titleholders won 2-1 at Parma in Serie A on Saturday to maintain their 100 percent record.
Radja Nainggolan scored on his delayed Inter Milan debut to set them on the way to their first win of the season on Saturday as they beat Bologna 3-0 away in Serie A.
A late stoppage-time goal by substitute Patrick Cutrone gave AC Milan a 2-1 home win over Roma in an electrifying Serie A clash on Friday and eased the pressure on manager Gennaro Gattuso.
Inter seemed to be in absolute control, but fumbled a 2-0 lead and risked losing the game against a plucky Torino.
Dries Mertens came off the bench to grab the winner as Napoli rallied from 2-0 down to beat visiting AC Milan 3-2 and seize a second victory in two matches.
Cristiano Ronaldo missed an open goal but inadvertently provided an assist for Mario Mandzukic to score as titleholders Juventus beat Lazio 2-0 in Serie A on Saturday.
Inter Milan's hopes of challenging for the Serie A title got off on the wrong foot with a shock 1-0 defeat at Sassuolo on Sunday.
Roma striker Edin Dzeko scored with a memorable volleyed goal following a mazy run by debutant Justin Kluivert to give his side a 1-0 win at Torino in their opening Serie A game on Sunday.
Ciro Immobile scored a magnificent opener, but Arkadiusz Milik and Lorenzo Insigne completed the Napoli comeback to conquer Lazio.
Federico Bernardeschi scored in stoppage time to make Cristiano Ronaldo a winner on his Juventus debut as the Italian champions rallied to win 3-2 at Chievo Verona on Saturday.
Keita Balde completed his move from Monaco to Inter Milan on Monday after just one season at the Ligue 1 club.
Gonzalo Higuain has left Juventus and joined AC Milan in a deal that also sees Leonardo Bonucci return to Juve after a year away in a swap for fellow centre-back Mattia Caldara.
Cristiano Ronaldo is leaving Real Madrid to sign with Italian champions Juventus, both clubs announced on Tuesday.
AC Milan have been excluded from playing in the Europa League next season after breaching UEFA's financial fair play (FFP) regulations, pending an appeal.
Juventus have completed the signing of Portugal full-back Joao Cancelo from Valencia for a fee of €40.4 million, which will be paid in three installments.
Radja Nainggolan has completed his move from Roma to Inter Milan in a deal worth €38 million with Davide Santon and Nicolo Zaniolo moving in the opposite direction as part of the transfer.
Emre Can has joined Serie A champions Juventus from Liverpool on a four-year contract.
Juventus have confirmed the permanent signing of Bayern Munich winger Douglas Costa for a fee of €40 million.
Carlo Ancelotti has signed a three-year contract to replace Maurizio Sarri as Napoli's head coach.
Inter Milan came from behind to snatch the final Champions League place in their 3-2 winner-takes-all victory at Lazio.
AC Milan qualified for the Europa League group stage on the final day in Serie A, following a 5-1 win over Fiorentina.
Gianluigi Buffon said an emotional farewell to Juventus as the veteran goalkeeper marked his 640th and last Serie A appearance in a 2-1 victory over relegated Hellas Verona.
Juventus clinched a seventh straight Serie A title to continue their dominance in Italy despite labouring to a 0-0 draw at 10-man Roma.
Lazio missed a chance to clinch the fourth and final Italian place in next season's Champions League group stage when they were held to a 2-2 draw at relegation-threatened Crotone on Sunday.
Inter Milan's Champions League hopes suffered a huge blow as Sassuolo shocked them again at the San Siro in Serie A on Saturday.