Lazio salvaged a point at Napoli after goals from Keita and Marek Hamsik cancelled each other out in a frenetic two-minute spell at Stadio San Paolo.
Andrea Belotti scored twice as Torino blew Cagliari away 5-1 to reassert their European ambitions.
Inter Milan have confirmed they have parted company with head coach Frank De Boer, less than three months after appointing the former Ajax boss.
The pressure ramped up another notch on Inter Milan manager Frank de Boer after Sampdoria inflicted a fourth defeat in five Serie A games.
Roma blew their chance to keep the pressure on Serie A leaders Juventus as they were held to a goalless draw at struggling Empoli on Sunday.
Giacomo Bonaventura's second-half strike proved enough as AC Milan bounced back from the midweek defeat at Genoa with a 1-0 victory over Pescara at San Siro to move up to third in Serie A.
Gonzalo Higuain's second-half winner saw Juventus clinch their 22nd consecutive home win in Serie A with a 2-1 victory over Napoli.
Mauro Icardi took a major step towards regaining the adoration of hardcore Inter Milan fans while also throwing boss Frank de Boer a lifeline as his brace helped beat Torino 2-1 at San Siro.
Edin Dzeko continued his hot streak in front of goal as Roma battled back from a goal down to win 3-1 at Sassuolo.
Juventus warmed up for their top-of-the-table clash with Napoli by beating Sampdoria 4-1 in Turin.
AC Milan missed the chance to go top of Serie A as they were beaten 3-0 at Genoa.
Roma reinforced their Serie A title credentials with a confident 4-1 home victory over Palermo.
Nikola Kalinic grabbed a hat-trick as Fiorentina came from behind to thump Cagliari 5-3.
Frank de Boer's future as Inter Milan head coach is under serious threat after the Nerazzurri went down 2-1 to Atalanta in Bergamo.
Teenager Manuel Locatelli fired AC Milan to a hard-earned 1-0 win over Serie A leaders Juventus at the San Siro as Vincenzo Montella's young side continued their impressive start to the season.
Two goals from Adem Ljajic helped Torino come from behind to pick up their third win on the bounce with a 4-1 Serie A victory over Palermo.
AC Milan extended their unbeaten run against Chievo to 20 matches and climbed up to third in Serie A with a 3-1 win on the road.
Samir Handanovic's late own goal secured Cagliari a third straight Serie A win and sent Inter Milan spiralling to a third successive defeat in all competitions.
Paulo Dybala's set-piece double saw Serie A leaders Juventus come from behind to defeat Udinese 2-1 at home and extend their lead at the top of the table to five points.
A counter-attacking masterclass saw Roma earn a 3-1 victory against Napoli in their Serie A clash at Stadio San Paolo.
Kostas Manolas had the final word in Roma's scintillating 2-1 victory over Inter Milan.
Gabriel Paletta's first ever AC Milan goal settled a 4-3 thriller against Sassuolo at San Siro.
Iago Falque scored one goal and set up another as Torino reached eighth place with a 2-1 Serie A victory over Fiorentina at the Stadio Olimpico.
Andrea Petagna ended Napoli's unbeaten start to the Serie A season by firing Atalanta to a 1-0 win.
Juventus ensured they would end the weekend in first place in Serie A with a convincing 3-0 victory at Empoli.
Ciro Immobile scored twice as Lazio won 3-0 at Udinese to move third in Serie A.
Josip Ilicic missed a first-half penalty as Fiorentina were held to a goalless draw by AC Milan, who were indebted to goalkeeper Gianluigi Donnarumma at the Artemio Franchi Stadium.
Inter Milan had to be content with a point against Bologna after a fine volley from Ivan Perisic saw them recover to draw 1-1 at Stadio Giuseppe Meazza.
Iago Falque's brace handed Joe Hart's Torino a home victory over Roma for the first time since 1990 as Sinisa Mihajlovic's side prevailed 3-1 in Serie A.
Marek Hamsik scored his 100th goal for Napoli as the Serie A title challengers beat Chievo 2-0.
Douglas Costa scored the only goal as Juventus closed to within a point of Serie A leaders Napoli following a workmanlike 1-0 victory over Genoa.
Matias Velcino's header four minutes from time earned Inter Milan a deserved 1-1 draw against Roma at Stadio Giuseppe Meazza.
Napoli avenged their Coppa Italia defeat to Atalanta with a 1-0 victory in Bergamo.
Juventus remained within a point of Serie A leaders Napoli ahead of the winter break as Federico Bernardeschi's second-half strike secured a 1-0 win at Cagliari.
AC Milan defender Leonardo Bonucci scored his first goal for the club in a 1-0 win over Crotone -- although the Italy international knew little about it.
Giovanni Simeone scored a dramatic stoppage-time equaliser as Fiorentina fought back to draw 1-1 against Inter Milan at the Stadio Franchi.
Three-time defending champion Juventus beat city rival Torino 2-0 to reach the Coppa Italia semifinals on Wednesday.
Medhi Benatia's first-half strike was enough as Juventus beat Roma 1-0 in Serie A to move within a point of leaders Napoli.
Marek Hamsik became the top scorer in Napoli's history, breaking Diego Maradona's long-standing club record with the winner in a 3-2 victory over Sampdoria on Saturday that extended their lead in Serie A to four points.
Inter Milan lost ground on Serie A league leaders Napoli ahead of the winter break as they lost 1-0 to Sassuolo.
AC Milan were booed off the pitch after falling to a second successive defeat, this time a 2-0 at home to Atalanta.
Juventus playmaker Paulo Dybala scored his first goal for a month to send the titleholders on their way to a 2-0 win over Genoa in the Coppa Italia on Wednesday and set up a quarter-final against neighbours Torino.
Reigning champions Juventus stormed back into second place in the Serie A table, while AC Milan's imploding season took another turn for the worse.
AC Milan's imploding season took another turn for the worse as Gennaro Gattuso's 10 men were thrashed 3-0 at Hellas Verona.
Napoli took full advantage of Inter Milan's first defeat of the Serie A season to take over at the top.
Udinese ended Inter Milan's unbeaten start to the Serie A season and led them to surrender the top spot after winning 3-1 at San Siro.
AC Milan recorded their first league win since Nov. 5 and their first under new coach Gennaro Gattuso as they beat Bologna 2-1.
Roma were unable to find a way past an inspired Stefano Sorrentino as they were held to a goalless draw at Chievo.
Inter Milan remain in top spot in Serie A after holding Juventus to a goalless draw in Turin.
Inter Milan moved a point clear at the top of Serie A as an Ivan Perisic hat trick helped them to a 5-0 victory over Chievo.
Benevento goalkeeper Alberto Brignoli scored with a diving header five minutes into injury time to seal his side's first Serie A point in a 2-2 draw with AC Milan on Sunday.
Serie A leaders Napoli surrendered their unbeaten start to the season as Juventus striker Gonzalo Higuain returned to haunt his former club with the only goal in a 1-0 win.
Edin Dzeko ended his goal drought with the opener as Roma beat 10-man SPAL 3-1 on Friday evening.
Second-half goals from Mario Mandzukic, Mattia De Sciglio and Medhi Benatia saw reigning champions Juventus recover from their setback at Sampdoria last weekend with a 3-0 win over Crotone in Serie A on Sunday.
Roma moved fourth and ahead of rivals Lazio thanks to a 1-1 draw at Genoa.
Napoli returned to the top of Serie A following a narrow 1-0 win at Udinese.
AC Milan's miserable Serie A run continued as Torino held them to a 0-0 draw at San Siro.
Inter Milan moved to the top of the Serie A table with a hard-fought 3-1 victory against a resurgent Cagliari on Saturday night.
Mauro Icardi scored two headers to fuel Inter Milan, who jumped Juventus for second place with a 2-0 win over Atalanta.
Juventus fell to a surprise 3-2 defeat at Sampdoria, who maintained their perfect Serie A home record on Sunday.