Tottenham proved themselves capable of coping without Harry Kane as they sailed into the last 16 of the Europa League with a 3-0 win over Fiorentina.
Liverpool scraped past Augsburg and into the last 16 of the Europa League after a nervy 1-0 win at Anfield.
Borussia Dortmund recorded their fifth straight win in all competitions by defeating Porto 1-0 at the Estadio do Dragao to advance beyond the Europa League's last 32.
Manchester United's chances of progressing in the Europa League are in the balance after they threw away the lead to go down 2-1 at FC Midtjylland in the first leg of their Europa League last-32 tie.
Tottenham remain in the hunt for three trophies this season after leaving Italy with a hard-fought draw in their Europa League round of 32 tie against Fiorentina.
Goals from Lukasz Piszczek and Marco Reus handed Borussia Dortmund a 2-0 victory over Porto in the first leg of their Europa League last-32 tie.
Galatasaray and Lazio played out a 1-1 draw in the first leg of their Europa League last-32 clash in Istanbul.
Under-fire Valencia boss Gary Neville enjoyed the perfect 41st birthday as his side thrashed Rapid Vienna 6-0 in the first leg of their Europa League last-32 tie.
Denis Suarez's brilliant late free-kick gave Villarreal a narrow lead to take to Italy in their Europa League last-32 tie with Napoli.
Jurgen Klopp's homecoming did not go exactly to plan as his Liverpool side were held to a goalless draw against Augsburg in Germany.
Manchester United have been drawn against Danish champions Midtjylland in the Europa League round of 32, while Liverpool will play Augsburg.
Borussia Dortmund face a difficult draw for the Europa League round of 32 and could face the likes of Manchester United - or Jurgen Klopp's Liverpool - after losing 1-0 at home to PAOK and finishing as runners-up in Group C.
Celtic's Europa League hopes were ended for the season as Ajax substitute Vaclav Cerny scored a late winner for the visitors at Parkhead.
Christian Benteke's brilliant strike saw Liverpool beat Bordeaux 2-1 to qualify for the knockout stages of the Europa League with a match to spare.
Borussia Dortmund conceded a penalty in the first minute and ceded top spot in their Europa League group to opponents Krasnodar with a 1-0 defeat on Thursday.
Harry Kane fired Tottenham into the knockout stages of the Europa League as they finally overcame stubborn Group J minnows Qarabag 1-0 in Baku.
Jurgen Klopp is starting to build some momentum at Liverpool after a third successive victory - the club's first away from home in Europe for nearly three years.
Mousa Dembele scored a stunning late winner as Tottenham beat Anderlecht 2-1 to move top of Group J in the Europa League.
Borussia Dortmund secured their place in the knockout stage after routing Azerbaijan side Qabala 4-0 in Group C.
Stefano Okaka scored and Anderlecht rallied to hand Tottenham a 2-1 defeat in the Europa League on Thursday.
Liverpool settled for a 1-1 draw at Anfield against Swiss side FC Sion in the Europa League on Thursday.
Liverpool manager Brendan Rodgers' Europa League gamble almost paid off as the club's young guns were held to a 1-1 draw in Bordeaux.
Son Heung-Min scored a quick-fire brace on his home debut as Tottenham came from behind to beat Qarabag in their Europa League opener on Thursday night.
Basel took revenge on Paulo Sousa, as Fiorentina fumbled a lead to lose 2-1 at home with Gonzalo Rodriguez sent off.
Napoli started the Europa League in style, demolishing Club Brugge 5-0 with Jose Callejon and Dries Mertens braces.
Park Joo-Ho headed a last-gasp winner as Borussia Dortmund came from behind to launch their Europa League campaign with a 2-1 win over Krasnodar.
A late goal from substitute Lasse Schone gave Ajax a 2-2 draw against Celtic at the Amsterdam ArenA where Hoops left-back Emilio Izaguirre was sent off.
Tottenham Hotspur have been handed a tough draw in the group stage of the Europa League.
Thomas Tuchel pronounced himself "generally happy" after his Borussia Dortmund side crushed Odds BK 7-2 in their Europa League qualifier second leg on Thursday.
Southampton were sent crashing out of Europe on Thursday evening courtesy of a strike from FC Midtjylland's very own "Big Dunc."
Burnley's European adventure came to an end on Friday as the Premier League side crashed out of the Europa League playoff round with a 1-1 draw against Olympiakos.
Celtic were held to a 1-1 draw by Lithuanian side Suduva Marijampole in the first leg of their Europa League play-off at the ARVI Futbolo Arena.
Antoine Griezmann struck twice as Atletico Madrid powered past Marseille to lift their third Europa League title in nine years.
Atletico Madrid advanced to the Europe League final 2-1 on aggregate after a 1-0 victory over Arsenal at the Wanda Metropolitano on Thursday.
Marseille scored a dramatic extra-time decider against Red Bull Salzburg to earn a Europa League final showdown with Atletico Madrid in Lyon on May 16.
If Arsene Wenger's Arsenal finale is to be a Europa League final in Lyon his side will have to do it the hard way after surrendering a well-deserved lead to draw against 10-man Atletico Madrid in the first leg of their semi-final.
Florian Thauvin put Marseille within touching distance of a place in the UEFA Europa League final with a controversial opener as his side beat Red Bull Salzburg 2-0 at the Stade Velodrome.
Arsenal will face Atletico Madrid later this month in their first appearance in the Europa League semifinals since 2000.
Marseille stunned RB Leipzig 4-2 in a thrilling Europa League quarterfinal second leg at the Orange Velodrome on Thursday evening to secure a 5-3 aggregate victory.
Red Bull Salzburg came from behind to earn a stunning 4-1 victory that secured an unlikely Europa League semifinal berth at the expense of Lazio.
Arsenal edged into the semifinals of the Europa League, but only after surviving a major scare as CSKA Moscow threatened a memorable comeback.
Atletico Madrid overcame a scare to see off the challenge of a fired-up Sporting Lisbon and book their place in the semifinals of the Europa League.
Aaron Ramsey and Alexandre Lacazette each scored twice as Mesut Ozil put on a Europa League masterclass to overwhelm CSKA Moscow and all but book Arsenal's place in the semifinals.
Timo Werner pounced in first-half injury time as RB Leipzig edged the first leg of their quarter-final against Marseille.
Two goals in two second-half minutes helped Lazio beat Salzburg 4-2 and take control of their Europa League quarter-final.
Koke scored after 23 seconds to set Atletico Madrid on their way to a routine 2-0 win over Sporting Lisbon in the first leg of their Europa League quarterfinal.
Arsenal will play Russian club CSKA Moscow in the quarterfinals as they look to win the Europa League for the first time and seal a place in next season's Champions League.
Danny Welbeck scored twice against AC Milan to toast his England recall by sending Arsenal into the last eight of the Europa League.
Fernando Torres scored twice as Europa League favourites Atletico Madrid hammered Lokomotiv Moscow 5-1 in Russia to advance to the quarterfinal stage.
Valon Berisha scored twice as Salzburg earned a 2-1 win away to Borussia Dortmund in the first leg of their Europa League round-of-16 tie on Thursday.
Arsenal eased to victory over AC Milan to move towards a place in the quarterfinals of the Europa League and end a run of four consecutive defeats in the process.
Atletico Madrid grabbed a sizable advantage over Lokomotiv Moscow by earning a 3-0 victory in the first leg of their Europa League round-of-16 clash on Thursday.
Celtic crashed out of the Europa League in calamitous style with a 3-0 defeat to Zenit St Petersburg in Russia.
Kevin Gameiro scored Atletico Madrid's only goal as a 1-0 win over Copenhagen was enough to advance from the Europa League round of 32 on the back of a big victory last week.
Serie A leaders Napoli were knocked out on away goals despite a 2-0 win away to RB Leipzig on Thursday.
Arsenal survived a major scare to secure their spot in the last 16 of the Europa League despite suffering an embarrassing 2-1 home defeat to Ostersund.
Borussia Dortmund made nervous work of their Europa League second leg against Atalanta in a 1-1 draw that saw the Bundesliga side reach the round of 16 courtesy of a 4-3 aggregate final.
Italian leaders Napoli suffered a surprise 3-1 home defeat at the hands of RB Leipzig as Timo Werner scored twice.
Celtic defeated Zenit St Petersburg 1-0 at Hampden Park in the first leg of their Europa League.
Michy Batshuayi scored twice, including a late winner, to rally Borussia Dortmund to a 3-2 win over Atalanta in their opening game of the Europe League knockout stage.