Southampton made a winning start to their Europa League campaign and gave Claude Puel his first win as manager with a convincing 3-0 defeat of Sparta Prague.
Three-time European champions Inter Milan were humbled at home by Hapoel Be'er Sheva in a 2-0 defeat in their Europa League opener on Thursday.
Jairo Riedewald scored the winner as Ajax came from behind to record a 2-1 Europa League victory at Panathinaikos as English referee Andre Marriner showed three red cards.
On-loan defender Baba Rahman scored the only goal as Schalke got their Europa League Group I campaign off to a winning start in Nice.
Manchester United will face Fenerbahce and Feyenoord in Group A in the 2016-17 Europa League.
Premier League side West Ham failed to claim a place in the group stage of the Europa League as they were beaten by Romanian champions Astra Giurgiu.
West Ham suffered more jitters against Astra Giurgiu as they were held to a 1-1 draw in the first leg of their Europa League playoff on Thursday.
West Ham must navigate a trip to Romania if they are to reach the Europa League group stages after being pitted against Astra Giurgiu in the play-off round.
West Ham United marked their first match at the Olympic Stadium with a 3-0 win over Slovenian side NK Domzale on Thursday as Cheikhou Kouyate scored twice to help secure a place in the Europa League playoff round.
West Ham endured a chastening 2-1 defeat to minnows NK Domzale in the first leg of their Europa League third-round qualifier in Slovania on Thursday.
Sevilla lifted the Europa League trophy for a third successive season by beating Liverpool 3-1 in the final in Basel, Switzerland, on Wednesday night.
Liverpool manager Jurgen Klopp is confident he has fulfilled his promise to make doubters believers ahead of the Europa League final against Sevilla.
Liverpool reached their first European final for nine years with a comprehensive 3-0 win over a 10-man Villarreal side who lost their heads in the red-hot cauldron of Anfield.
Kevin Gameiro scored twice as Sevilla once again saved their best form for the Europa League and stormed into their third straight final with a 3-1 second-leg win over Shakhtar Donetsk.
Villarreal beat Liverpool 1-0 in the first leg of their Europa League semifinal at El Madrigal through an injury time Adrian Lopez goal.
Sevilla stayed on course for a third straight Europa League title by claiming a 2-2 draw against Shakhtar Donetsk in Ukraine in the first leg of their semifinal.
Jurgen Klopp's Liverpool will take on Villarreal for a place in the final of the Europa League.
Sevilla remain on course for a third successive Europa League title after securing a dramatic 5-4 penalty shootout victory over Athletic Bilbao in the quarterfinals at the Estadio Ramon Sanchez Pizjuan.
Cedric Bakambu scored twice as Villarreal glided to a 4-2 win at Sparta Prague to advance 6-3 on aggregate.
Captain Darijo Srna toasted breaking Shakhtar Donetsk's all-time appearance record by blasting the penalty that sent the Ukrainians into the Europa League semi-finals.
Liverpool incredibly stormed into the Europa League semifinals 5-4 on aggregate after an improbable 4-3 defeat of Borussia Dortmund in their second leg tie on Thursday at Anfield.
Substitute Vicente Iborra struck seven minutes from time to keep Sevilla on course for a third straight UEFA Europa League title after a 2-1 win at Athletic Bilbao.
Liverpool striker Divock Origi fully justified his manager's faith with a vital away goal against Borussia Dortmund and a 1-1 draw on Jurgen Klopp's homecoming that kept everyone happy.
Shakhtar Donetsk soaked up pressure from Braga and then scored in either half to take a 2-1 away win in the first leg of their Europa League quarterfinal.
The in-form Cedric Bakambu scored twice as Villarreal took a 2-1 first-leg lead in their Europa League quarterfinal against Sparta Prague.
Liverpool will face Borussia Dortmund in the Europa League quarterfinals in a clash that sees Jurgen Klopp come up against his former club.
Philippe Coutinho's moment of brilliance extinguished Manchester United's faint hopes and saw Liverpool through to the Europa League quarter-finals.
Tottenham were left to focus fully on their Premier League title challenge as Mauricio Pochettino's side bowed of the Europa League last 16 following a 2-1 defeat to Borussia Dortmund.
Villarreal shut out Bayer Leverkusen to book their place in the quarterfinals of the Europa League.
Aritz Aduriz struck late on as Athletic Bilbao edged past Gary Neville's Valencia on away goals to reach the Europa League quarterfinals.
Sevilla suffered a shock defeat by Russians Krasnodar, going down 2-1 in Europa League Group J.
Ten-man Celtic threw away an early lead to succumb to a 3-1 defeat to Red Bull Salzburg in Austria.
Alvaro Morata provided the lone goal in Chelsea's 1-0 win over Vidi in Europa League group-stage action on Thursday.
Emile Smith Rowe scored his first career goal in Arsenal's 3-0 win over FK Qarabag in Europa League group-stage action on Thursday.
Substitute Patrick Cutrone netted twice in nine minutes to lift AC Milan to a 3-1 comeback win at home to Olympiakos in Europa League group-stage action.
Arsenal's superb form continued into the Europa League as they thrashed Ukrainian side Vorksla Poltava 4-2 on Thursday.
Gonzalo Higuain's deflected effort in the 59th minute sealed a 1-0 victory for AC Milan over Luxembourg side F91 Dudelange on Thursday night in Europa League action.
Chelsea's Europa League campaign kicked off in style with a 1-0 win at PAOK Salonika on Thursday.
Leigh Griffiths made the difference for Celtic in their Europa League opener, coming off the bench to score a late winner against Rosenborg.
Burnley's European adventure came to an end on Friday as the Premier League side crashed out of the Europa League playoff round with a 1-1 draw against Olympiakos.
Celtic were held to a 1-1 draw by Lithuanian side Suduva Marijampole in the first leg of their Europa League play-off at the ARVI Futbolo Arena.
Antoine Griezmann struck twice as Atletico Madrid powered past Marseille to lift their third Europa League title in nine years.
Atletico Madrid advanced to the Europe League final 2-1 on aggregate after a 1-0 victory over Arsenal at the Wanda Metropolitano on Thursday.
Marseille scored a dramatic extra-time decider against Red Bull Salzburg to earn a Europa League final showdown with Atletico Madrid in Lyon on May 16.
If Arsene Wenger's Arsenal finale is to be a Europa League final in Lyon his side will have to do it the hard way after surrendering a well-deserved lead to draw against 10-man Atletico Madrid in the first leg of their semi-final.
Florian Thauvin put Marseille within touching distance of a place in the UEFA Europa League final with a controversial opener as his side beat Red Bull Salzburg 2-0 at the Stade Velodrome.
Arsenal will face Atletico Madrid later this month in their first appearance in the Europa League semifinals since 2000.
Marseille stunned RB Leipzig 4-2 in a thrilling Europa League quarterfinal second leg at the Orange Velodrome on Thursday evening to secure a 5-3 aggregate victory.
Red Bull Salzburg came from behind to earn a stunning 4-1 victory that secured an unlikely Europa League semifinal berth at the expense of Lazio.
Arsenal edged into the semifinals of the Europa League, but only after surviving a major scare as CSKA Moscow threatened a memorable comeback.
Atletico Madrid overcame a scare to see off the challenge of a fired-up Sporting Lisbon and book their place in the semifinals of the Europa League.
Aaron Ramsey and Alexandre Lacazette each scored twice as Mesut Ozil put on a Europa League masterclass to overwhelm CSKA Moscow and all but book Arsenal's place in the semifinals.
Timo Werner pounced in first-half injury time as RB Leipzig edged the first leg of their quarter-final against Marseille.
Two goals in two second-half minutes helped Lazio beat Salzburg 4-2 and take control of their Europa League quarter-final.
Koke scored after 23 seconds to set Atletico Madrid on their way to a routine 2-0 win over Sporting Lisbon in the first leg of their Europa League quarterfinal.
Arsenal will play Russian club CSKA Moscow in the quarterfinals as they look to win the Europa League for the first time and seal a place in next season's Champions League.
Danny Welbeck scored twice against AC Milan to toast his England recall by sending Arsenal into the last eight of the Europa League.
Fernando Torres scored twice as Europa League favourites Atletico Madrid hammered Lokomotiv Moscow 5-1 in Russia to advance to the quarterfinal stage.
Valon Berisha scored twice as Salzburg earned a 2-1 win away to Borussia Dortmund in the first leg of their Europa League round-of-16 tie on Thursday.
Arsenal eased to victory over AC Milan to move towards a place in the quarterfinals of the Europa League and end a run of four consecutive defeats in the process.