Lionel Messi became the record Champions League goalscorer and Luis Suarez opened his account for Barcelona as the Catalan giants cruised to a 4-0 win over APOEL Nicosia.
Sergio Aguero struck twice in the closing minutes to complete a hat-trick and revive Manchester City's Champions League hopes with a 3-2 win over 10-man Bayern Munich.
Roberto Di Matteo played down the talk of a revenge mission as Chelsea visited Gelsenkirchen to take on his Schalke side, but it was embarrassment that greeted the Italian as his former side eased into the knockout stages of the Champions League with a 5-
Hector Herrera helped ease Porto into pole position to claim top spot in Champions League Group H with a 3-0 victory over BATE Borisov.
Mikel San Jose kept Athletic Bilbao's European hopes alive by ending Shakhtar Donetsk's chances of topping Champions League Group H.
Paris Saint-Germain maintained their edge over Barcelona at the top of Champions League Group F with a comfortable 3-1 win over Ajax at the Parc des Princes.
Vasili Berezutski kept CSKA Moscow's Champions League campaign alive with a last-gasp equaliser against Roma which also did Manchester City a huge favour.
Lionel Messi equalled Raul's record of 71 Champions League goals with a brace to earn Barcelona a 2-0 win over Ajax in Group F.
Bayern Munich ensured they will finish top of Group E in the Champions League with two games to spare after a 2-0 victory over Roma.
Chelsea must wait to secure qualification from Champions League Group G after Eden Hazard missed a late penalty in a 1-1 draw against minnows Maribor.
Paris Saint-Germain caught Apoel Nicosia cold to open the scoring 58 seconds into their Champions League encounter in the French capital, and were glad they did as they endured growing frustration for the rest of the night.
For the second time in a fortnight BATE Borisov were thrashed by Shakhtar Donetsk, who followed up their 7-0 romp in Belarus with a 5-0 victory on Wednesday night.
In-form Porto sealed their place in the Champions League knockout stages with a 2-0 win over Group H strugglers Athletic Bilbao.
Islam Slimani scored for both teams to top and tail a thrilling Champions League clash as Sporting Lisbon beat Schalke 4-2.
Fernandinho and Yaya Toure were sent off as Manchester City crashed to a damaging 2-1 home defeat to CSKA Moscow in the Champions League.
Arsenal spurned the chance to book their place in the Champions League knockout stages as they threw away a three-goal lead to draw 3-3 with Anderlecht.
Predictions of a rout proved to be well wide the mark as Liverpool's weakened side produced a disciplined if not ultimately successful performance at the Bernabeu.
Juventus just about edged a topsy-turvy Group A encounter with Olympiakos to put themselves in a strong position to qualify for the knockout stages of the Champions League.
Atletico Madrid moved ever closer towards a place in the knockout stages of the Champions League with a 2-0 win at Group A rivals Malmo on Tuesday night.
Borussia Dortmund put their domestic troubles to one side to book their place in the knock-out stages of the Champions League with a comfortable 4-1 win over Galatasaray marred by some ugly scenes in the stands.
Taslica scored a valuable goal to give Benfica their first win in Champions League Group C as they claimed a hard fought 1-0 victory over Monaco on Tuesday night.
A second-half double from Son Heung-min earned Bayer Leverkusen an impressive 2-1 win at Zenit St Petersburg which put them on the brink of the Champions League knockout stage.
Real Madrid showed exactly why they are European champions and how far Liverpool have fallen down the pecking order with a 3-0 victory in a display which oozed class at Anfield.
Substitute Lukas Podolski netted a dramatic late winner as Arsenal came from behind with two goals in the final two minutes to beat Anderlecht 2-1.
A Koke-inspired Atletico Madrid scored five second-half goals in a comprehensive victory over Malmo to go top of Champions League Group A on Wednesday.
Olympiakos edged Juventus 1-0 on Wednesday night in Piraeus after a first-half goal from Pajtim Kasami.
Borussia Dortmund maintained their perfect start to their Champions League campaign with a comprehensive 4-0 victory over Galatasaray in Group D.
Bayer Leverkusen boosted their hopes of advancing from Champions League Group C on Wednesday night with a 2-0 victory over previously unbeaten Zenit St Petersburg.
Monaco and Benfica played out a goalless Champions League Group C draw at the Stade Louis II on Wednesday.
Yordan Minev's last-gasp strike lifted Ludogorets to a famous Champions League victory over 10-man Basle.
Cristiano Ronaldo's Champions League debut for Juventus lasted only 29 minutes as he was red-carded but the Italians began their Group H campaign impressively with a 2-0 victory at Valencia on Wednesday.
Paul Pogba scored two first-half goals as Manchester United spoiled Young Boys' first appearance in the group stage of the Champions League by cruising to a comfortable 3-0 victory at the Stade de Suisse on Wednesday.
Manchester City looked far from potential Champions League winners as they fell to a surprise 2-1 loss at home to Olympique Lyonnais on Wednesday with a flat performance that leaves them with plenty of work to do to progress from Group F.
CSKA Moscow salvaged a 2-2 draw with Viktoria Plzen in the Champions League on Wednesday after a penalty deep in stoppage time.
Bayern Munich midfielder Renato Sanches had a goal and an assist in his return to Benfica in a 2-0 victory on Wednesday.
Real Madrid rode goals from Isco and Gareth Bale to a 3-0 win against Roma in their Champions League Group G opener at the Camp Nou on Wednesday.
The youngest coach in Champions League history drew his debut game Wednesday as Hoffenheim's match at Shakhtar Donetsk finished 2-2.
Nicolas Tagliafico scored two second-half goals as Ajax marked their return to the Champions League group stages with a 3-0 victory over AEK Athens on Wednesday.
A stoppage-time goal from Roberto Firmino gave Liverpool a 3-2 win over Paris Saint-Germain on a dramatic Champions League night at Anfield.
Red Star Belgrade ground out a 0-0 home draw against Napoli on the Serbian side's Champions League debut as their goalkeeper Milan Borjan made a flurry of telling saves in a pulsating Group C clash on Tuesday.
Borussia Dortmund's United States forward Christian Pulisic came off the bench to grab a late goal for a 1-0 Champions League Group A victory over Club Brugge on Tuesday.
Atletico Madrid battled their way back from a goal down to pull off a confidence-boosting 2-1 win at AS Monaco in Champions League Group A on Tuesday, with a defiant response to their troubling start to the domestic season.
Inter Milan scored two late goals as they came from 1-0 down to beat Tottenham Hotspur 2-1 in a dramatic Champions League clash at the San Siro.
Lionel Messi scored a record-setting hat trick as Barcelona opened their Champions League campaign in Group B with an impressive 4-0 win against PSV Eindhoven at the Camp Nou.
Juventus will face Manchester United in the Champions League group stage this season, giving Cristiano Ronaldo a chance to play against his former team.
A thrilling draw away to Salzburg enabled Serbian champions Red Star Belgrade to reach the Champions League group stage for the first time where they will be joined by Portugal's Benfica and Dutch side PSV Eindhoven.
Four-time European champion Ajax qualified for the Champions League group stage on Tuesday for the first time in four years, while AEK Athens and Young Boys Bern ended even longer absences.
Former European Cup winners Ajax Amsterdam stayed firmly on course to reach the Champions League group stage after a dazzling first half helped them to a 3-1 home win over Dynamo Kiev.
Former European Cup winners PSV Eindhoven fought back to grind out a 3-2 win at BATE Borisov on Tuesday in their Champions League playoff round first-leg clash while Benfica were held to a 1-1 home draw by PAOK.
Atletico Madrid finally got their own back on Real Madrid in European competition by snatching a 4-2 win over their city rivals after extra time to lift the UEFA Super Cup on Wednesday.
AEK Athens and PAOK Thessaloniki gave Greek football fans plenty to cheer about as both clubs reached the Champions League playoff round and joined three former winners of Europe's elite club competition on Tuesday.
Odsonne Edouard scored a brace to help Celtic to a 3-1 victory in the first-leg of their Champions League second round qualifying tie with Rosenborg in Glasgow.
Liverpool boss Jurgen Klopp believes Mo Salah is likely to miss the World Cup after leaving the Champions League final injured in the first half.
Gareth Bale said he wants to be playing every week -- which "has not happened this season" -- after leading Real Madrid to the Champions League trophy in Saturday's 3-1 win over Liverpool.
Cristiano Ronaldo cast doubt over his future with Real Madrid after they won the Champions League for the third consecutive season on Saturday in a 3-1 win over Liverpool.
Real Madrid beat Liverpool 3-1 to win the Champions League for a third successive season thanks to a spectacular two-goal substitute appearance from Gareth Bale and a performance to forget for Loris Karius.
Liverpool set up a repeat of their 1981 meeting against Real Madrid despite a first Champions League defeat of the season at the Stadio Olimpico.
Two goals from Karim Benzema helped Real Madrid advance to their third straight Champions League final 4-3 on aggregate after a scintillating 2-2 draw with Bayern Munich in the second leg of their last-four clash on Tuesday.
Real Madrid will be firm favourites to reach another Champions League final after winning 2-1 away to Bayern Munich in the first leg of their semifinal.
Liverpool scored five but conceded two late goals as Roma gave themselves a glimmer of hope in a 5-2 defeat at Anfield after the home side had swept into a huge lead.