Wolfsburg booked their expected place in the quarter-finals of the Champions League for the first time in their history as Andre Schurrle's late goal earned them an unconvincing 1-0 home win over Gent.
Manchester City produced one of their best performances of the season to seize the advantage in their Champions League last-16 tie with a superb 3-1 win at Dynamo Kiev.
PSV Eindhoven survived the dismissal of Gaston Pereiro to hold Atletico Madrid to a goalless Champions League draw at the Philips Stadion.
Barcelona took the advantage over Arsenal in their round of 16 clash at the Emirates on Tuesday night as they won 2-0 thanks to two goals from Lionel Messi.
Juventus came from two goals down to earn a 2-2 draw in the first leg of their Champions League last-16 tie with Bayern Munich.
Real Madrid beat Roma 2-0 in their Champions League last-16 first leg at the Stadio Olimpico, with away goals from Cristiano Ronaldo and Jese giving them the upper hand.
Gent gave themselves a Champions League lifeline with two late goals in a 3-2 home defeat against Wolfsburg.
Zlatan Ibrahimovic and Edinson Cavani scored as Paris Saint-Germain took a 2-1 advantage over Chelsea in the first leg of their Champions League last-16 clash on Tuesday.
Benfica have a slender 1-0 advantage over Zenit St Petersburg after Oliveira Jonas' injury-time goal at the Estadio da Luz.
Barcelona and Argentina star Lionel Messi was awarded the 2015 Ballon d'Or at Monday's gala event in Zurich.
With four players each from Barcelona and Real Madrid, the Spanish giants combined to put eight players on the 2015 FIFPro World XI.
The highlight of the Champions League last-16 draw sees Arsenal take on Barcelona and Juventus take on Bayern Munich.
Jose Mourinho received a slice of luck and another reprieve as Chelsea advanced to the knockout stages of the Champions League as Group G winners with a 2-0 victory over his former club Porto.
Olivier Giroud inspired Arsenal to complete a Champions League group stage comeback as his hat trick at Olympiakos sealed their place in the last 16.
Bayer Leverkusen could not find a winner against Barcelona as their final Champions League Group E match ended 1-1, which saw the German side fail to qualify for the last 16 and drop into the Europa League.
Robert Lewandowski notched a quickfire brace as Bayern Munich rounded off their Champions League Group F fixtures with a 2-0 win at Dinamo Zagreb.
Gent beat Group H winners Zenit St Petersburg 2-1 at Ghelamco Arena to become the first Belgian club to get through to the knockout stages of the Champions League in 15 years.
Gary Neville watched his Valencia team slide into the Europa League after his Mestalla debut saw Lyon claim a 2-0 Champions League victory.
Denys Garmash's goal was enough to give Dynamo Kiev a 1-0 win over Maccabi Tel Aviv and send them through to the knockout stages of the Champions League.
Roma squeezed through to the Champions League last 16 after being held to a 0-0 draw at home by BATE Borisov in their final Group E game.
CSKA Moscow were unable to pull off a shock win over PSV Eindhoven, and United now face the prospect of playing Europa League football in the new year.
Sevilla will try to defend their Europa League crown after a 1-0 home win over Juventus secured them third place in Champions League Group D.
Raheem Sterling celebrated his 21st birthday with a quickfire double to send Manchester City through to the Champions League last 16 as group winners.
PSV Eindhoven secured their place in the knockout stages of the Champions League with a late 2-1 win against Group B's bottom club CSKA Moscow.
Cristiano Ronaldo and Karim Benzema both scored hat-tricks as Real Madrid hammered Malmo 8-0 to equal the highest ever victory in the Champions League.
Shakhtar Donetsk held on to a Europa League place despite suffering a fifth defeat in six games in Champions League Group A against Paris Saint-Germain.
Atletico Madrid clinched first place in Champions League Group C after winning their top-of-the-table encounter with Benfica 2-1 at the Estadio da Luz.
Galatasaray secured themselves a Europa League spot with a 1-1 Champions League Group C draw against Astana.
Mario Mandzukic scored the only goal as Juventus leapfrogged Manchester City in Champions League Group D with a 1-0 win in Turin.
Manchester United were held to a goalless draw by PSV Eindhoven at Old Trafford on Wednesday night, meaning their Champions League hopes will depend on their final group game away at Wolfsburg.
Liverpool boss Jurgen Klopp believes Mo Salah is likely to miss the World Cup after leaving the Champions League final injured in the first half.
Gareth Bale said he wants to be playing every week -- which "has not happened this season" -- after leading Real Madrid to the Champions League trophy in Saturday's 3-1 win over Liverpool.
Cristiano Ronaldo cast doubt over his future with Real Madrid after they won the Champions League for the third consecutive season on Saturday in a 3-1 win over Liverpool.
Real Madrid beat Liverpool 3-1 to win the Champions League for a third successive season thanks to a spectacular two-goal substitute appearance from Gareth Bale and a performance to forget for Loris Karius.
Liverpool set up a repeat of their 1981 meeting against Real Madrid despite a first Champions League defeat of the season at the Stadio Olimpico.
Two goals from Karim Benzema helped Real Madrid advance to their third straight Champions League final 4-3 on aggregate after a scintillating 2-2 draw with Bayern Munich in the second leg of their last-four clash on Tuesday.
Real Madrid will be firm favourites to reach another Champions League final after winning 2-1 away to Bayern Munich in the first leg of their semifinal.
Liverpool scored five but conceded two late goals as Roma gave themselves a glimmer of hope in a 5-2 defeat at Anfield after the home side had swept into a huge lead.
Liverpool will face Roma in the semifinals of the Champions League later this month as they continue their attempt to win it for the first time since 2005.
Cristiano Ronaldo scored an injury-time penalty to book Real Madrid's place in the Champions League semifinals after losing the second leg 3-1, but winning the tie 4-3 on aggregate.
Bayern Munich are through to the Champions League semifinals for the seventh time in nine years after a 0-0 draw in their quarterfinal second leg with Sevilla.
Barcelona suffered a shock Champions League defeat at the hands of Roma, losing 3-0 in their quarterfinal second leg at the Stadio Olimpico to go out 4-4 on aggregate thanks to an away goal for the Serie A side in the first leg.
Mohamed Salah and Roberto Firmino scored second-half goals as Liverpool won 2-1 at Manchester City to reach the Champions League semifinals 5-1 on aggregate.
A pair of own goals helped Barcelona take a major step toward the Champions League semifinals with a 4-1 win over Roma at the Camp Nou on Wednesday.
Liverpool drew significant first blood in their all-English Champions League quarterfinal as Manchester City were blown away in 45 minutes in a raucous 3-0 Anfield defeat.
Bayern Munich fought back from a goal down to beat Sevilla 2-1 in their Champions League quarterfinal first leg on Tuesday night at the Ramon Sanchez Pizjuan.
Cristiano Ronaldo scored a spectacular brace to hand Real Madrid a 3-0 victory over Juventus in their Champions League quarterfinal first leg on Tuesday.
Liverpool face Manchester City in an all-English Champions League quarterfinal after the draw in Switzerland on Friday.
Two goals from Lionel Messi -- one the fastest of his career and the other his 100th in the Champions League -- helped Barcelona beat Chelsea 3-0 at the Camp Nou and advance to the quarterfinals 4-1 on aggregate.
Bayern Munich coasted into the quarterfinals of the Champions League with a 3-1 win over Besiktas in Istanbul to complete an 8-1 aggregate win.
A second-half strike from Edin Dzeko sent Roma into the quarterfinals of the Champions League with a 1-0 home victory against 10-man Shakhtar Donetsk.
Sevilla are through to the Champions League quarterfinals after beating Manchester United 2-1 in their second leg at Old Trafford on Tuesday night.
Manchester City slipped to their first home defeat since December 2016 as Basel won the second leg of their Champions League last-16 tie 2-1.
Two goals in under three second-half minutes saw Juventus come back from 1-0 down to knock Tottenham Hotspur out of the Champions League, with a 2-1 win at Wembley putting them through to the quarterfinals 4-3 on aggregate.
Liverpool eased into the quarterfinals of the Champions League for the first time in nine years with no great alarm in a lifeless goalless draw at home to Porto.
Holders Real Madrid eased into the Champions League quarterfinals with a 2-1 win at 10-man Paris Saint-Germain.
David De Gea's exceptional display saved Manchester United's blushes as Jose Mourinho's men somehow escaped with a goalless draw from a match dominated by Sevilla.
Shakhtar Donetsk pulled off a second-half comeback to beat Roma 2-1 in their Champions League round-of-16 first leg in Ukraine on Wednesday night.
Bayern Munich look assured of a Champions League quarterfinal spot for a seventh straight season after thrashing 10-man Besiktas 5-0 in Germany.
Lionel Messi broke his goal duck against Chelsea to deny Antonio Conte's side a crucial lead over Barcelona in their Champions League showdown.