Harry Kane lifted Tottenham's Wembley curse by scoring twice and firing his side to an opening Champions League win over Borussia Dortmund.
Manchester City produced an outstanding performance to open their seventh successive Champions League campaign with an emphatic 4-0 win at Feyenoord.
Liverpool's Champions League return did not go entirely to plan as they repeatedly shot themselves in the foot in the 2-2 draw at home to Sevilla.
Last season's semifinalist Monaco were held 1-1 by upstarts RB Leipzig at Red Bull Arena in the clubs' Group G opener.
Shakhtar Donetsk stunned Napoli 2-1 at Metalist Stadium thanks to goals from Taison and Facundo Ferreyra.
Besiktas started their Champions League Group G campaign with a 3-1 win against Porto at the Estadio do Dragao.
Maribor and Spartak Moscow played out a 1-1 draw in their Champions League Group E opener as a referee narrowly escaped being hit by a flare.
Cristiano Ronaldo scored twice to help Real Madrid open their Champions League campaign with a 3-0 win over Apoel on Wednesday.
Lionel Messi summoned another mesmerising performance as Barcelona breezed to a 3-0 win over Juventus in their UEFA Champions League Group D opener at the Camp Nou.
Chelsea marked their Champions League return with a 6-0 Group C rout of Azerbaijan's Qarabag, but sterner tests await.
Free-spending Paris St Germain demonstrated their prowess with a 5-0 thumping of Celtic in their Champions League opener at Parkhead.
Saul Niguez squandered a gilt-edged chance to snatch Champions League victory at the death as Atletico Madrid had to make do with a goalless draw against Roma.
CSKA Moscow forward Timur Zhamaletdinov made a memorable Champions League debut on Tuesday by scoring the winner in a 2-1 comeback victory at Benfica in Group A.
Five-time champions Bayern Munich opened their Champions League campaign with a flattering 3-0 win over 10-man Anderlecht on Tuesday.
Olympiakos conceded a goal after just 69 seconds of their Champions League campaign and went on to lose 3-2 to Sporting Lisbon at home in Group D on Tuesday.
Manchester United eased back into Champions League life as Marouane Fellaini, Romelu Lukaku and Marcus Rashford put Basle to the sword.
Barcelona and Juventus will renew their recent rivalry when they meet at the Camp Nou in the group stage of the UEFA Champions League on Tuesday.
Real Madrid's Cristiano Ronaldo was named UEFA's Player of the Year, beating Lionel Messi and Gianluigi Buffon to the prize.
Champions League holders Real Madrid will face Borussia Dortmund and Tottenham in a difficult group following the draw ceremony in Monaco on Thursday.
The 32 teams in this season's Champions League group stage can now begin to think about their dream draw after the final seeding pots were confirmed following Wednesday's final qualifying ties.
Liverpool scored three times in a devastating opening 21 minutes as they reached the Champions League group stage with a 6-3 aggregate win over Bundesliga side Hoffenheim at Anfield.
Celtic progressed into the Champions League group stage as expected with an 8-4 aggregate win over Astana, but they were made to sweat in their 4-3 second-leg defeat in Kazakhstan.
Second-half goals from Jose Callejon and Lorenzo Insigne earned Napoli a 2-0 win in Nice and ensured their qualification for the Champions League group stages.
Goals from Dries Mertens and Jorginho were enough to earn Napoli a 2-0 win against Nice in their Champions League qualifying play-off first leg.
Celtic put one foot into the Champions League group stages with a 5-0 thumping of Astana in the first leg of their playoff at Parkhead.
Trent Alexander-Arnold scored his first Liverpool goal as Jurgen Klopp's side took a 2-1 lead in their Champions League qualifier against Hoffenheim.
Manchester United were outclassed at times as Real Madrid won the UEFA Super Cup to give Jose Mourinho food for thought at the start of his second season in the hot seat.
Liverpool will have to overcome Hoffenheim in a two-legged playoff to reach the group stages of the Champions League.
James Forrest's second-half strike gave Celtic a 1-0 win over Rosenborg and took the Hoops another step closer towards Champions League football.
Ajax failed to make it through to the Champions League qualifiers for the third consecutive year on Wednesday when they were eliminated on the away goals rule 3-3 on aggregate after a 2-2 home draw against Ligue 1 side Nice.
Lorenzo Insigne's late winner gave Napoli a deserved 1-0 Champions League victory over Liverpool on Wednesday that saw the Italians move to the top of Group C.
Mauro Icardi took advantage of an error from PSV Eindhoven goalkeeper Jeroen Zoet to gift Inter Milan a 2-1 victory in their Champions League Group B clash on Wednesday.
Borussia Dortmund's blistering start to the season under manager Lucien Favre gathered momentum as the Bundesliga leaders consigned ailing Monaco to a 3-0 defeat in the Champions League on Wednesday.
Antoine Griezmann had a goal in each half -- including the 8,000th Champions League goal -- and Koke also scored in added time to lead Atletico Madrid to a 3-1 win over Club Brugge on Wednesday.
A second-half header by Moussa Marega gave Porto a 1-0 Champions League win over Galatasaray at home on Wednesday.
Lionel Messi scored twice and powered Barcelona to a 4-2 win against Tottenham in Champions League Group B at Wembley Stadium on Wednesday night.
United States international Weston McKennie's late header gave Schalke a 1-0 win over Lokomotiv Moscow in the Champions League on Wednesday as they continued to recover from a poor start to the season.
Neymar scored his second Champions League hat trick as Paris Saint-Germain rolled to a 6-1 victory over Red Star Belgrade in a Champions League group-stage game at the Parc des Princes on Wednesday.
Roma's Edin Dzeko was again the tormentor for Viktoria Plzen as he scored a hat trick in a 5-0 Champions League Group G win for the Italian side on Tuesday.
Manchester United's dismal run of form continued as they were held to a 0-0 draw by Valencia in a drab Champions League clash at Old Trafford.
Lyon produced a stirring fightback to claw back two superb goals from Shakhtar Donetsk's Junior Moraes and rescue a 2-2 draw behind closed doors in a thrilling end-to-end contest at their Groupama Stadium on Tuesday.
A depleted Real Madrid suffered a shock 1-0 Champions League defeat at CSKA Moscow on Tuesday, extending a poor run of form for the holders that has left them without a win in three games.
Benfica played the entire second half with 10 men and squandered a two-goal lead before claiming a thrilling 3-2 win away to AEK Athens in Champions League Group E action on Tuesday.
Full-back Noussair Mazraoui earned a youthful Ajax side a 1-1 draw at misfiring Bayern Munich in their Champions League Group E clash at the Allianz Arena on Tuesday.
Paulo Dybala hit a hat-trick as Juventus maintained their 100% record in the Champions League courtesy of a 3-0 win against BSC Young Boys.
David Silva nipped in to secure a late 2-1 victory for Premier League champions Manchester City at Hoffenheim.
Cristiano Ronaldo's Champions League debut for Juventus lasted only 29 minutes as he was red-carded but the Italians began their Group H campaign impressively with a 2-0 victory at Valencia on Wednesday.
Paul Pogba scored two first-half goals as Manchester United spoiled Young Boys' first appearance in the group stage of the Champions League by cruising to a comfortable 3-0 victory at the Stade de Suisse on Wednesday.
Manchester City looked far from potential Champions League winners as they fell to a surprise 2-1 loss at home to Olympique Lyonnais on Wednesday with a flat performance that leaves them with plenty of work to do to progress from Group F.
CSKA Moscow salvaged a 2-2 draw with Viktoria Plzen in the Champions League on Wednesday after a penalty deep in stoppage time.
Bayern Munich midfielder Renato Sanches had a goal and an assist in his return to Benfica in a 2-0 victory on Wednesday.
Real Madrid rode goals from Isco and Gareth Bale to a 3-0 win against Roma in their Champions League Group G opener at the Camp Nou on Wednesday.
The youngest coach in Champions League history drew his debut game Wednesday as Hoffenheim's match at Shakhtar Donetsk finished 2-2.
Nicolas Tagliafico scored two second-half goals as Ajax marked their return to the Champions League group stages with a 3-0 victory over AEK Athens on Wednesday.
A stoppage-time goal from Roberto Firmino gave Liverpool a 3-2 win over Paris Saint-Germain on a dramatic Champions League night at Anfield.
Red Star Belgrade ground out a 0-0 home draw against Napoli on the Serbian side's Champions League debut as their goalkeeper Milan Borjan made a flurry of telling saves in a pulsating Group C clash on Tuesday.
Borussia Dortmund's United States forward Christian Pulisic came off the bench to grab a late goal for a 1-0 Champions League Group A victory over Club Brugge on Tuesday.
Atletico Madrid battled their way back from a goal down to pull off a confidence-boosting 2-1 win at AS Monaco in Champions League Group A on Tuesday, with a defiant response to their troubling start to the domestic season.
Inter Milan scored two late goals as they came from 1-0 down to beat Tottenham Hotspur 2-1 in a dramatic Champions League clash at the San Siro.
Lionel Messi scored a record-setting hat trick as Barcelona opened their Champions League campaign in Group B with an impressive 4-0 win against PSV Eindhoven at the Camp Nou.