Wayne Rooney became Manchester United's all-time leading scorer in Europe as Jose Mourinho's side defeated Feyenoord 4-0 to move to the brink of qualifying for the Europa League's last 32.
Southampton's hopes of reaching the Europa League's knockout stages have been left in the balance after a 1-0 defeat at Sparta Prague.
The battle to join Ajax in progressing from Group G of the Europa League will go to the final day as Celta Vigo and Standard Liege drew 1-1.
Substitute Ben Sahar scored an injury-time winner as Hapoel Be'er Sheva came from two goals down to beat 10-man Inter Milan 3-2 and set up a winner-takes-all clash with Southampton.
Wayne Rooney's late long-range strike was not enough to salvage a draw for Manchester United as they lost 2-1 to Fenerbahce in the Europa League.
Edin Dzeko struck twice as Roma beat Europa League rivals Austria Vienna 4-2 at the Ernst Happel Stadium to move top of Group E.
A brace from Giuliano undid Dundalk in Europa League Group D as they went down 2-1 to Zenit St Petersburg in Russia.
Southampton beat Inter Milan 2-1 to secure a famous victory that takes them to the brink of the Europa League's knockout stages.
Paul Pogba scored twice as Manchester United defeated Fenerbahce 4-1 to move to the top of Europa League Group A.
Southampton wasted the chance to take a significant step towards the Europa League's knockout stages with a disappointing 1-0 defeat at Inter Milan.
Alassane Plea's first-half strike handed Nice their first ever European away victory as they secured a 1-0 Europa League win over Salzburg.
Celta Vigo and Ajax shared four goals in an entertaining 2-2 draw to keep themselves at the head of Europa League Group G.
Dundalk tasted bitter disappointment as they went from the verge of an historic victory to defeat against Zenit St Petersburg.
Manchester United laboured to a 1-0 Europa League victory over Zorya Luhansk at Old Trafford as Zlatan Ibrahimovic headed home in the second half to seal the points for the below-par hosts.
Francesco Totti capped a memorable week with three assists as Roma thrashed Astra Giurgiu 4-0 in Group E of the Europa League.
Southampton secured a valuable point in their bid to progress to the Europa League's knockout stages with a 0-0 draw as Hapoel Be'er Sheva continued their extraordinary undefeated record at the Turner Stadium.
Some terrible defensive errors and a sluggish approach saw Inter beaten 3-1 at Sparta Prague in the Europa League, plus Andrea Ranocchia sent off.
An undercooked and underperforming Manchester United started their Europa League campaign with a 1-0 defeat as Tonny Vilhena secured Feyenoord a late victory.
Sassuolo marked their debut in the Europa League with a 3-0 win over seasoned campaigners Athletic Bilbao.
Southampton made a winning start to their Europa League campaign and gave Claude Puel his first win as manager with a convincing 3-0 defeat of Sparta Prague.
Three-time European champions Inter Milan were humbled at home by Hapoel Be'er Sheva in a 2-0 defeat in their Europa League opener on Thursday.
Jairo Riedewald scored the winner as Ajax came from behind to record a 2-1 Europa League victory at Panathinaikos as English referee Andre Marriner showed three red cards.
On-loan defender Baba Rahman scored the only goal as Schalke got their Europa League Group I campaign off to a winning start in Nice.
Manchester United will face Fenerbahce and Feyenoord in Group A in the 2016-17 Europa League.
Premier League side West Ham failed to claim a place in the group stage of the Europa League as they were beaten by Romanian champions Astra Giurgiu.
West Ham suffered more jitters against Astra Giurgiu as they were held to a 1-1 draw in the first leg of their Europa League playoff on Thursday.
West Ham must navigate a trip to Romania if they are to reach the Europa League group stages after being pitted against Astra Giurgiu in the play-off round.
West Ham United marked their first match at the Olympic Stadium with a 3-0 win over Slovenian side NK Domzale on Thursday as Cheikhou Kouyate scored twice to help secure a place in the Europa League playoff round.
West Ham endured a chastening 2-1 defeat to minnows NK Domzale in the first leg of their Europa League third-round qualifier in Slovania on Thursday.
Sevilla lifted the Europa League trophy for a third successive season by beating Liverpool 3-1 in the final in Basel, Switzerland, on Wednesday night.
Arsenal have been drawn against Swedish club Ostersunds FK in the Europa League round of 32, while Atletico Madrid take on Copenhagen.
Ademola Lookman's brace ensured a youthful Everton side did not miss Sam Allardyce's presence in Cyprus as they finished their woeful Europa League campaign with a victory.
AC Milan concluded their Europa League group stage with a 2-0 defeat at Croatian club Rijeka on Thursday.
Arsenal cruised to victory over BATE Borisov in their final Europa League group game as Arsene Wenger's fringe players made another case for Premier League involvement.
AC Milan booked their place in the Europa League's final 32 with a 5-1 win over Austria Vienna on Thursday night.
Arsenal failed to get the point they needed to guarantee topping Europa League Group H as Cologne beat them 1-0 in Germany -- but they finished first anyway as Red Star Belgrade and BATE Borisov drew 0-0.
Everton's season, like their search for a manager, continues to drift as an insipid display brought a 5-1 home Europa League home thrashing by Atalanta.
AC Milan were made to wait for confirmed qualification from the Europa League group stage after being held to a 0-0 draw in a mediocre game at AEK Athens.
Arsenal qualified from the Europa League group stage despite being held to a 0-0 home draw by Red Star Belgrade, with rivals BATE Borisov being thrashed 5-2 in Cologne.
Managerless Everton crashed out of the Europa League with two Group E games left to play as they were beaten 3-0 at Lyon.
Mario Balotelli gave Nice an early lead but it was not enough to prevent Lazio from emerging convincing 3-1 winners at the Stade de Nice.
Everton boss Ronald Koeman was forced to endure more disappointment as Lyon consigned his side to an ill-tempered defeat and more Europa League misery.
Olivier Giroud scored a stunning winner as a much-changed Arsenal side saw off 10-man Red Star Belgrade in their Europa League clash.
Theo Walcott scored twice and Olivier Giroud notched his 100th Arsenal goal as the Londoners secured a second successive Europa League win, triumphing 4-2 at BATE Borisov.
AC Milan lost a 2-0 lead at the San Siro but found an injury time goal to earn a 3-2 win over Croatian champions Rijeka in the Europa League.
Everton's poor start in the Europa League continued as they were held to a 2-2 draw at Goodison Park by Cypriot outfit Apollon Limassol, who finished the game with 10 men.
Arsenal came from behind to beat Cologne in their delayed Europa League opener against a backdrop of crowd trouble at the Emirates Stadium.
Everton produced another hugely disappointing display as they were beaten 3-0 by Atalanta in their Europa League Group E opener in Reggio Emilia.
Andre Silva scored a hat trick as AC Milan eased to a 5-1 victory over Austria Vienna in their Europa League group-stage opener.
Arsenal have been drawn alongside BATE Borisov, Cologne and Red Star Belgrade in the Europa League group stage.
AC Milan eased into the Europa League group stage with a 1-0 win over Shkendija on Thursday, though the result was in little doubt after the Rossoneri won the first leg 6-0 a week ago.
Gylfi Sigurdsson marked his first Everton start with a spectacular goal to help put Ronald Koeman's side into the group stages of the Europa League after a 1-1 away draw with Hajduk Split.
Everton play Croatian side Hajduk Split in the Europa League playoff round, while AC Milan have been drawn against Macedonian side Shkendija.
AC Milan are through to the Europa League playoff round after beating Universitatea Craiova 3-0 on aggregate following a 2-0 second-leg win in the third qualifying round on Thursday.
Dominic Calvert-Lewin's calm finish kept Everton's bid for Europa League qualification on course as Ronald Koeman's men edged MFK Ruzomberok 1-0 in Slovakia.
AC Milan's offseason spending spree paid a quick dividend when new signing Ricardo Rodriguez scored in a 1-0 win at CSU Craiova.
Wayne Rooney's Everton return threatened to turn into embarrassment before captain Leighton Baines struck to give his side a slender first-leg lead in their Europa League third qualifying round clash with Ruzemberok.
Ajax manager Peter Bosz was left unimpressed by Jose Mourinho's Manchester United in the wake of the Premier League side's 2-0 Europa League final triumph on Wednesday, though he admitted his side were deserved losers on the night.
Ander Herrera has admitted it was difficult for the Manchester United players to train in the build up to the Europa League final after the terrorist attack that devastated Manchester on Monday.
Jose Mourinho has labelled Manchester United's Europa League triumph as "the most important trophy" of his career, while adding he was happy to call time on a season that was perhaps his most difficult as a manager.