Manchester United will play Belgian club Anderlecht in the Europa League quarterfinals.
Schalke booked their spot in the quarterfinals via the away goals rule after rallying for a 2-2 draw at Borussia Monchengladbach.
A Juan Mata goal gave Manchester United a 1-0 win over Rostov at Old Trafford to send them into the Europa League quarterfinals with a 2-1 victory on aggregate.
Roma recovered from a poor start to lead 2-1 at half-time, but crumbled after the break for a 4-2 defeat to Olympique Lyonnais.
Manchester United scored an important away goal as they earned a 1-1 draw against FC Rostov in their Europa League round-of-16 first leg.
Tottenham paid the price for a Dele Alli horror-tackle as Mauricio Pochettino's side drew 2-2 with Gent and crashed out of the Europa League last 32.
Lyon trounced AZ Alkmaar 7-1 to win their Europa League last-32 tie 11-2 on aggregate, while Borussia Monchengladbach staged a comeback to knock out Fiorentina.
Manchester United wrapped up a commanding 4-0 aggregate Europa League victory over St Etienne, winning 1-0 in the away leg thanks to an early Henrikh Mkhitaryan goal and easing into the round of 16.
Edin Dzeko's hat trick helped Roma run out 4-0 winners against Villarreal at the Estadio El Madrigal.
Zlatan Ibrahimovic's first Manchester United hat trick saw off St Etienne as Jose Mourinho's men took control of this Europa League round-of-32 tie.
A below-par Tottenham Hotspur lost the first leg of their Europa League round-of-32 game against Gent 1-0 in Belgium.
Manchester United will take on St Etienne in the Europa League's round of 32, while Tottenham Hotspur will face Gent and Villarreal have been drawn against Roma.
Celta Vigo claimed their place in the last 32 of the Europa League with a straightforward 2-0 win over Panathinaikos in Athens.
Manu Trigueros scored a superb late winner as Villarreal reached the Europa League knockout stages with a nervy 2-1 victory over 10-man Steaua Bucharest.
Toothless Southampton missed the chance for a best European run since 1977 after Israeli minnows Hapoel Be'er Sheva drew 1-1 at St Mary's to knock them out of the Europa League.
Fine goals by Henrikh Mkhitaryan and Zlatan Ibrahimovic gave Manchester United a 2-0 away win over Zorya Luhansk and booked their place in the Europa League knockout stages as group runners-up.
Wayne Rooney became Manchester United's all-time leading scorer in Europe as Jose Mourinho's side defeated Feyenoord 4-0 to move to the brink of qualifying for the Europa League's last 32.
Southampton's hopes of reaching the Europa League's knockout stages have been left in the balance after a 1-0 defeat at Sparta Prague.
The battle to join Ajax in progressing from Group G of the Europa League will go to the final day as Celta Vigo and Standard Liege drew 1-1.
Substitute Ben Sahar scored an injury-time winner as Hapoel Be'er Sheva came from two goals down to beat 10-man Inter Milan 3-2 and set up a winner-takes-all clash with Southampton.
Wayne Rooney's late long-range strike was not enough to salvage a draw for Manchester United as they lost 2-1 to Fenerbahce in the Europa League.
Edin Dzeko struck twice as Roma beat Europa League rivals Austria Vienna 4-2 at the Ernst Happel Stadium to move top of Group E.
A brace from Giuliano undid Dundalk in Europa League Group D as they went down 2-1 to Zenit St Petersburg in Russia.
Southampton beat Inter Milan 2-1 to secure a famous victory that takes them to the brink of the Europa League's knockout stages.
Paul Pogba scored twice as Manchester United defeated Fenerbahce 4-1 to move to the top of Europa League Group A.
Southampton wasted the chance to take a significant step towards the Europa League's knockout stages with a disappointing 1-0 defeat at Inter Milan.
Alassane Plea's first-half strike handed Nice their first ever European away victory as they secured a 1-0 Europa League win over Salzburg.
Celta Vigo and Ajax shared four goals in an entertaining 2-2 draw to keep themselves at the head of Europa League Group G.
Dundalk tasted bitter disappointment as they went from the verge of an historic victory to defeat against Zenit St Petersburg.
Manchester United laboured to a 1-0 Europa League victory over Zorya Luhansk at Old Trafford as Zlatan Ibrahimovic headed home in the second half to seal the points for the below-par hosts.
Arsenal will play Russian club CSKA Moscow in the quarterfinals as they look to win the Europa League for the first time and seal a place in next season's Champions League.
Danny Welbeck scored twice against AC Milan to toast his England recall by sending Arsenal into the last eight of the Europa League.
Fernando Torres scored twice as Europa League favourites Atletico Madrid hammered Lokomotiv Moscow 5-1 in Russia to advance to the quarterfinal stage.
Valon Berisha scored twice as Salzburg earned a 2-1 win away to Borussia Dortmund in the first leg of their Europa League round-of-16 tie on Thursday.
Arsenal eased to victory over AC Milan to move towards a place in the quarterfinals of the Europa League and end a run of four consecutive defeats in the process.
Atletico Madrid grabbed a sizable advantage over Lokomotiv Moscow by earning a 3-0 victory in the first leg of their Europa League round-of-16 clash on Thursday.
Celtic crashed out of the Europa League in calamitous style with a 3-0 defeat to Zenit St Petersburg in Russia.
Kevin Gameiro scored Atletico Madrid's only goal as a 1-0 win over Copenhagen was enough to advance from the Europa League round of 32 on the back of a big victory last week.
Serie A leaders Napoli were knocked out on away goals despite a 2-0 win away to RB Leipzig on Thursday.
Arsenal survived a major scare to secure their spot in the last 16 of the Europa League despite suffering an embarrassing 2-1 home defeat to Ostersund.
Borussia Dortmund made nervous work of their Europa League second leg against Atalanta in a 1-1 draw that saw the Bundesliga side reach the round of 16 courtesy of a 4-3 aggregate final.
Italian leaders Napoli suffered a surprise 3-1 home defeat at the hands of RB Leipzig as Timo Werner scored twice.
Celtic defeated Zenit St Petersburg 1-0 at Hampden Park in the first leg of their Europa League.
Michy Batshuayi scored twice, including a late winner, to rally Borussia Dortmund to a 3-2 win over Atalanta in their opening game of the Europe League knockout stage.
Arsenal made light work of sub-zero temperatures and an artificial pitch to secure a comfortable Europa League victory over Ostersunds.
Patrick Cutrone scored a glancing header and earned a penalty converted by Ricardo Rodriguez as Milan conquered Ludogorets 3-0 in Bulgaria.
Arsenal have been drawn against Swedish club Ostersunds FK in the Europa League round of 32, while Atletico Madrid take on Copenhagen.
Ademola Lookman's brace ensured a youthful Everton side did not miss Sam Allardyce's presence in Cyprus as they finished their woeful Europa League campaign with a victory.
AC Milan concluded their Europa League group stage with a 2-0 defeat at Croatian club Rijeka on Thursday.
Arsenal cruised to victory over BATE Borisov in their final Europa League group game as Arsene Wenger's fringe players made another case for Premier League involvement.
AC Milan booked their place in the Europa League's final 32 with a 5-1 win over Austria Vienna on Thursday night.
Arsenal failed to get the point they needed to guarantee topping Europa League Group H as Cologne beat them 1-0 in Germany -- but they finished first anyway as Red Star Belgrade and BATE Borisov drew 0-0.
Everton's season, like their search for a manager, continues to drift as an insipid display brought a 5-1 home Europa League home thrashing by Atalanta.
AC Milan were made to wait for confirmed qualification from the Europa League group stage after being held to a 0-0 draw in a mediocre game at AEK Athens.
Arsenal qualified from the Europa League group stage despite being held to a 0-0 home draw by Red Star Belgrade, with rivals BATE Borisov being thrashed 5-2 in Cologne.
Managerless Everton crashed out of the Europa League with two Group E games left to play as they were beaten 3-0 at Lyon.
Mario Balotelli gave Nice an early lead but it was not enough to prevent Lazio from emerging convincing 3-1 winners at the Stade de Nice.
Everton boss Ronald Koeman was forced to endure more disappointment as Lyon consigned his side to an ill-tempered defeat and more Europa League misery.
Olivier Giroud scored a stunning winner as a much-changed Arsenal side saw off 10-man Red Star Belgrade in their Europa League clash.
Theo Walcott scored twice and Olivier Giroud notched his 100th Arsenal goal as the Londoners secured a second successive Europa League win, triumphing 4-2 at BATE Borisov.