Rafael Benitez's Napoli all but booked their place in the Europa League semifinals with a stunning 4-1 win over Wolfsburg in Germany on Thursday night.
A glorious late strike from Denis Suarez helped Sevilla come from behind to beat Zenit St Petersburg 2-1 in the first leg of their Europa League quarter-final in Spain.
Club Brugge were held to a goalless draw against Dnipro in their Europa League quarterfinal first leg encounter at the Jan Breydel Stadion on Thursday.
Substitute Khouma Babacar's goal in stoppage-time gave Fiorentina a 1-1 draw and a crucial away goal in their Europa League quarter-final first leg against Dynamo Kiev.
Wolfsburg and Napoli are to meet in the quarterfinals of the Europa League following Friday's draw for the last eight.
Everton crashed out of the Europa League after being punished for poor defending by a ruthless Dynamo Kiev side in Ukraine.
Brilliant Fiorentina stunned Roma with an early goal blitz to seal their spot in the Europa League quarterfinals at the expense of their Italian rivals.
Wolfsburg progressed to the last eight of the Europa League with a 2-1 second-leg victory away to Roberto Mancini's Inter Milan.
Sevilla remain on course to retain their Europa League title after easing past Spanish rivals Villarreal to reach the quarterfinals.
Napoli are through to the quarterfinals of the Europa League after a hard-fought goalless draw against Dinamo Moscow in Russia.
Zenit St Petersburg booked their place in the Europa League quarterfinals despite going down 1-0 to a late headed goal from Torino's Kamil Glik at the Stadio Olimpico.
Yevhen Konoplyanka's extra-time strike booked Dnipro's place in the quarter-finals of the Europa League on away goals despite a 2-1 second-leg defeat to Ajax in Amsterdam.
Vitolo scored the fastest goal in Europa League history as holders Sevilla took a giant step towards the quarter-finals with a 3-1 away victory over Spanish rivals Villarreal.
Roma rallied after falling behind to an early Josip Ilicic goal to draw 1-1 with Fiorentina in their Europa League last-16 tie at Stadio Artemio Franchi.
Gonzalo Higuain plundered a hat trick as Napoli recovered from an early fright to seize a commanding advantage against 10-man Dinamo Moscow in the Europa League.
Everton once again produced a Europa League performance in contrast to their domestic displays as Romelu Lukaku's late penalty secured them a 2-1 come-from-behind victory in their last-16 first leg against Dynamo Kiev.
Kevin De Bruyne inspired Wolfsburg to a 3-1 win over Inter Milan to put the Germans in control of their Europa League last-16 tie.
Dnipro claimed a deserved win over Ajax from the first leg of their Europa League last-16 tie in Kiev, but may rue not building a bigger advantage to take to Amsterdam.
Zenit St Petersburg took a big step towards the Europa League quarterfinals with a 2-0 win over 10-man Torino in the first leg of their last-16 clash.
Everton will face Dynamo Kiev in the last 16 of the Europa League while holders Sevilla were drawn against fellow Spaniards Villarreal.
Liverpool lost their first European penalty shoot-out as Dejan Lovren was the only man to miss from the spot against Besiktas in Istanbul.
Torino got the better of a back-and-forth battle in torrential rain to eliminate Athletic Bilbao from the Europa League.
Roma progressed to the last 16 of the Europa League with victory over Feyenoord but the match was overshadowed by crowd trouble in Rotterdam.
Everton comfortably completed their progress into the last 16 of the Europa League as a Romelu Lukaku brace helped them beat Young Boys 3-1 at Goodison Park, sealing a 7-2 win on aggregate.
Celtic's Europa League campaign came to a frustrating end with a 1-0 defeat by Inter Milan at the San Siro after Hoops defender Virgil van Dijk was dismissed in the first half.
Roberto Soldado's embarrassing mistake paved the way for Tottenham's Europa League exit against Fiorentina.
Wolfsburg repelled a string of Sporting Lisbon attacks to reach the last 16 of the Europa League with a goalless draw in Portugal.
Sevilla put aside their domestic problems to move into the last 16 of the Europa League - although the reigning champions were made to sweat by Borussia Monchengladbach before claiming a 3-2 second-leg win.
Luciano Vietto scored twice as Villarreal booked their place in the last 16 of the Europa League.
Zenit St Petersburg eased to a 4-0 aggregate win over runaway Eredivisie leaders PSV Eindhoven to reach the last 16 of the Europa League.
Arsenal will play Russian club CSKA Moscow in the quarterfinals as they look to win the Europa League for the first time and seal a place in next season's Champions League.
Danny Welbeck scored twice against AC Milan to toast his England recall by sending Arsenal into the last eight of the Europa League.
Fernando Torres scored twice as Europa League favourites Atletico Madrid hammered Lokomotiv Moscow 5-1 in Russia to advance to the quarterfinal stage.
Valon Berisha scored twice as Salzburg earned a 2-1 win away to Borussia Dortmund in the first leg of their Europa League round-of-16 tie on Thursday.
Arsenal eased to victory over AC Milan to move towards a place in the quarterfinals of the Europa League and end a run of four consecutive defeats in the process.
Atletico Madrid grabbed a sizable advantage over Lokomotiv Moscow by earning a 3-0 victory in the first leg of their Europa League round-of-16 clash on Thursday.
Celtic crashed out of the Europa League in calamitous style with a 3-0 defeat to Zenit St Petersburg in Russia.
Kevin Gameiro scored Atletico Madrid's only goal as a 1-0 win over Copenhagen was enough to advance from the Europa League round of 32 on the back of a big victory last week.
Serie A leaders Napoli were knocked out on away goals despite a 2-0 win away to RB Leipzig on Thursday.
Arsenal survived a major scare to secure their spot in the last 16 of the Europa League despite suffering an embarrassing 2-1 home defeat to Ostersund.
Borussia Dortmund made nervous work of their Europa League second leg against Atalanta in a 1-1 draw that saw the Bundesliga side reach the round of 16 courtesy of a 4-3 aggregate final.
Italian leaders Napoli suffered a surprise 3-1 home defeat at the hands of RB Leipzig as Timo Werner scored twice.
Celtic defeated Zenit St Petersburg 1-0 at Hampden Park in the first leg of their Europa League.
Michy Batshuayi scored twice, including a late winner, to rally Borussia Dortmund to a 3-2 win over Atalanta in their opening game of the Europe League knockout stage.
Arsenal made light work of sub-zero temperatures and an artificial pitch to secure a comfortable Europa League victory over Ostersunds.
Patrick Cutrone scored a glancing header and earned a penalty converted by Ricardo Rodriguez as Milan conquered Ludogorets 3-0 in Bulgaria.
Arsenal have been drawn against Swedish club Ostersunds FK in the Europa League round of 32, while Atletico Madrid take on Copenhagen.
Ademola Lookman's brace ensured a youthful Everton side did not miss Sam Allardyce's presence in Cyprus as they finished their woeful Europa League campaign with a victory.
AC Milan concluded their Europa League group stage with a 2-0 defeat at Croatian club Rijeka on Thursday.
Arsenal cruised to victory over BATE Borisov in their final Europa League group game as Arsene Wenger's fringe players made another case for Premier League involvement.
AC Milan booked their place in the Europa League's final 32 with a 5-1 win over Austria Vienna on Thursday night.
Arsenal failed to get the point they needed to guarantee topping Europa League Group H as Cologne beat them 1-0 in Germany -- but they finished first anyway as Red Star Belgrade and BATE Borisov drew 0-0.
Everton's season, like their search for a manager, continues to drift as an insipid display brought a 5-1 home Europa League home thrashing by Atalanta.
AC Milan were made to wait for confirmed qualification from the Europa League group stage after being held to a 0-0 draw in a mediocre game at AEK Athens.
Arsenal qualified from the Europa League group stage despite being held to a 0-0 home draw by Red Star Belgrade, with rivals BATE Borisov being thrashed 5-2 in Cologne.
Managerless Everton crashed out of the Europa League with two Group E games left to play as they were beaten 3-0 at Lyon.
Mario Balotelli gave Nice an early lead but it was not enough to prevent Lazio from emerging convincing 3-1 winners at the Stade de Nice.
Everton boss Ronald Koeman was forced to endure more disappointment as Lyon consigned his side to an ill-tempered defeat and more Europa League misery.
Olivier Giroud scored a stunning winner as a much-changed Arsenal side saw off 10-man Red Star Belgrade in their Europa League clash.
Theo Walcott scored twice and Olivier Giroud notched his 100th Arsenal goal as the Londoners secured a second successive Europa League win, triumphing 4-2 at BATE Borisov.